Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Prolactin-2

Gene

prl2

Organism
Oncorhynchus tshawytscha (Chinook salmon) (Salmo tshawytscha)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHormone

Names & Taxonomyi

Protein namesi
Recommended name:
Prolactin-2
Alternative name(s):
Prolactin II
Short name:
PRL-II
Gene namesi
Name:prl2
OrganismiOncorhynchus tshawytscha (Chinook salmon) (Salmo tshawytscha)
Taxonomic identifieri74940 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiProtacanthopterygiiSalmoniformesSalmonidaeSalmoninaeOncorhynchus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23By similarityAdd BLAST23
ChainiPRO_000003294324 – 210Prolactin-2Add BLAST187

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi69 ↔ 183By similarity
Disulfide bondi200 ↔ 210By similarity

Keywords - PTMi

Disulfide bond

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ91364
SMRiQ91364
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the somatotropin/prolactin family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

HOVERGENiHBG104895

Family and domain databases

InterProiView protein in InterPro
IPR009079 4_helix_cytokine-like_core
IPR001400 Somatotropin/Prolactin
IPR018116 Somatotropin_CS
PANTHERiPTHR11417 PTHR11417, 1 hit
PfamiView protein in Pfam
PF00103 Hormone_1, 1 hit
PRINTSiPR00836 SOMATOTROPIN
SUPFAMiSSF47266 SSF47266, 1 hit
PROSITEiView protein in PROSITE
PS00266 SOMATOTROPIN_1, 1 hit
PS00338 SOMATOTROPIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q91364-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARRSQGTKL HLAVLCLVVS CHAIGLSDLM ERASQRSDKL HSLSTSLNKD
60 70 80 90 100
LDSHFPPMGR VMMPRPSMCH TSSLQIPKDK EQALRVSENE LISLARSLLL
110 120 130 140 150
AWNDPLLLLS SEAPTLPHPS NGDISSKIRE LQDYSKSLGD GLDILVNKMG
160 170 180 190 200
PSSQYISLIP FKGGDLGNDK TSRLINFHFL MSCFRRDSHK IDSFLKVLRC
210
RATKMRPETC
Length:210
Mass (Da):23,457
Last modified:November 1, 1996 - v1
Checksum:iC3C0DBB0D87EA7B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S66606 Genomic DNA Translation: AAB28216.1

Similar proteinsi

Entry informationi

Entry nameiPRL2_ONCTS
AccessioniPrimary (citable) accession number: Q91364
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 16, 2001
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health