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Protein
Submitted name:

Activin beta B subunit

Gene

inhbb

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • embryonic axis specification Source: BHF-UCL
  • growth Source: InterPro
  • positive regulation of fibroblast growth factor receptor signaling pathway Source: BHF-UCL
Complete GO annotation...

Keywords - Molecular functioni

Growth factorUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Activin beta B subunitImported
Gene namesi
Name:inhbbImported
Synonyms:activin beta B subunitImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-5762117. inhbb.

Subcellular locationi

  • Secreted SAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 370351Sequence analysisPRO_5004318640Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

Protein-protein interaction databases

DIPiDIP-46064N.

Structurei

3D structure databases

ProteinModelPortaliQ91350.
SMRiQ91350. Positions 256-370.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini252 – 370119TGF_BETA_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the TGF-beta family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

HOVERGENiHBG105613.
KOiK04667.

Family and domain databases

Gene3Di2.10.90.10. 1 hit.
InterProiIPR029034. Cystine-knot_cytokine.
IPR000381. Inhibin_betaB.
IPR001318. Inhibin_betaC.
IPR001839. TGF-b_C.
IPR001111. TGF-b_N.
IPR015615. TGF-beta-rel.
IPR017948. TGFb_CS.
[Graphical view]
PANTHERiPTHR11848. PTHR11848. 1 hit.
PTHR11848:SF29. PTHR11848:SF29. 1 hit.
PfamiPF00019. TGF_beta. 1 hit.
PF00688. TGFb_propeptide. 1 hit.
[Graphical view]
PRINTSiPR00672. INHIBINBC.
SMARTiSM00204. TGFB. 1 hit.
[Graphical view]
SUPFAMiSSF57501. SSF57501. 1 hit.
PROSITEiPS00250. TGF_BETA_1. 1 hit.
PS51362. TGF_BETA_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91350-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALLLLPLLL AGLARTCAPS PTPEPGCPSC HPPMEPEMLE AVKRHILTLL
60 70 80 90 100
HMQDRPNITH MVPRAAMVSA LRKLHAGRVR EDGNLEIPDL DGHSLPPPGH
110 120 130 140 150
STENSAEIIT FAETDDVTAS RVRLSFTIAN EGNQNLFVFQ SNLWLYLKLP
160 170 180 190 200
EVMDKSRRKI RIKVHFQDAF NPDKMNMVEK KVDIRRSGWH TFPLTEAIQS
210 220 230 240 250
LFEEGERRLN LEVQCDGCGE YSVIPVYVDP GEESHRPFLV VHARLADNKH
260 270 280 290 300
RIRKRGLECD GHTNLCCRQQ FYIDFRLIGW NDWIIAPAGY YGNYCEGSCP
310 320 330 340 350
AYLAGVPGSA SSFHTAVVNQ YRMRGLNPGT VNSCCIPTKL STMSMLYFDD
360 370
EYNIVKRDVP NMIVDECGCA
Length:370
Mass (Da):41,679
Last modified:November 1, 1996 - v1
Checksum:iAD21502AC45F1DE9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S61773 mRNA. Translation: AAB26863.1.
PIRiB36192.
C36192.
I51199.
RefSeqiNP_001084055.1. NM_001090586.1.
UniGeneiXl.1090.

Genome annotation databases

GeneIDi399280.
KEGGixla:399280.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S61773 mRNA. Translation: AAB26863.1.
PIRiB36192.
C36192.
I51199.
RefSeqiNP_001084055.1. NM_001090586.1.
UniGeneiXl.1090.

3D structure databases

ProteinModelPortaliQ91350.
SMRiQ91350. Positions 256-370.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-46064N.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi399280.
KEGGixla:399280.

Organism-specific databases

CTDi3625.
XenbaseiXB-GENE-5762117. inhbb.

Phylogenomic databases

HOVERGENiHBG105613.
KOiK04667.

Family and domain databases

Gene3Di2.10.90.10. 1 hit.
InterProiIPR029034. Cystine-knot_cytokine.
IPR000381. Inhibin_betaB.
IPR001318. Inhibin_betaC.
IPR001839. TGF-b_C.
IPR001111. TGF-b_N.
IPR015615. TGF-beta-rel.
IPR017948. TGFb_CS.
[Graphical view]
PANTHERiPTHR11848. PTHR11848. 1 hit.
PTHR11848:SF29. PTHR11848:SF29. 1 hit.
PfamiPF00019. TGF_beta. 1 hit.
PF00688. TGFb_propeptide. 1 hit.
[Graphical view]
PRINTSiPR00672. INHIBINBC.
SMARTiSM00204. TGFB. 1 hit.
[Graphical view]
SUPFAMiSSF57501. SSF57501. 1 hit.
PROSITEiPS00250. TGF_BETA_1. 1 hit.
PS51362. TGF_BETA_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ91350_XENLA
AccessioniPrimary (citable) accession number: Q91350
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: July 6, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.