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Q91280

- UGT3_PLEPL

UniProt

Q91280 - UGT3_PLEPL

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Protein

UDP-glucuronosyltransferase

Gene

ugt3

Organism
Pleuronectes platessa (European plaice)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.

Catalytic activityi

UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.

GO - Molecular functioni

  1. glucuronosyltransferase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Protein family/group databases

CAZyiGT1. Glycosyltransferase Family 1.

Names & Taxonomyi

Protein namesi
Recommended name:
UDP-glucuronosyltransferase (EC:2.4.1.17)
Short name:
UDPGT
Gene namesi
Name:ugt3
OrganismiPleuronectes platessa (European plaice)
Taxonomic identifieri8262 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataCarangariaPleuronectiformesPleuronectoideiPleuronectidaePleuronectes

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei436 – 45621HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. endoplasmic reticulum Source: UniProtKB-KW
  2. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane, Microsome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini‹1 – 472›472UDP-glucuronosyltransferasePRO_0000074137Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi59 – 591N-linked (GlcNAc...)Sequence Analysis
Glycosylationi227 – 2271N-linked (GlcNAc...)Sequence Analysis
Glycosylationi377 – 3771N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ91280.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UDP-glycosyltransferase family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG004033.

Family and domain databases

InterProiIPR002213. UDP_glucos_trans.
[Graphical view]
PANTHERiPTHR11926. PTHR11926. 1 hit.
PfamiPF00201. UDPGT. 1 hit.
[Graphical view]
PROSITEiPS00375. UDPGT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q91280-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
LVPESSLFMH QSEDYETEVY PVSFTTEEMD ATHKQLKDGL FLKQPDWTEY
60 70 80 90 100
YVNIMRFVNF TSIHLRGCEN LLENQPLMSR MRGMGFDIVL TDPFFPCGAL
110 120 130 140 150
VGNIFSIPVV NFLRGLPCGL DMKVNKCPSP PSYIPVPYSG NTNIMTFPQR
160 170 180 190 200
VINMAMTVVE SYQCSLLYGH YDEMVSKYVG NNMDYRTLLS HGALWLIRNE
210 220 230 240 250
FTLDWPRPLL PNMVLIGGIN CAEKKKNASL PADLEEFVQG SGDDGFIIFT
260 270 280 290 300
LGSMLPDMPQ EKAQHFLDAF RQIPQRVVWR YAGDPPKGLP KNVRLMKWLP
310 320 330 340 350
QKELLAHPKA KLFLTHGGSH SVYEGICNAV PMLMFPLFAE QGDNGLRMVT
360 370 380 390 400
RGAAETLNIY DVTSDNLLAA LNKILKNKSY KEKITEMSQI HHDRPVAPLD
410 420 430 440 450
LAIFWTEFVI RHKGASHLRV AAHELNWIQY HSLDVFGFIL LILLTVLWVT
460 470
LKCCLFCTRR CCRRGTAKTK SE
Length:472
Mass (Da):53,781
Last modified:November 1, 1997 - v1
Checksum:iCCCC44363B54643B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X74116 mRNA. Translation: CAA52214.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X74116 mRNA. Translation: CAA52214.1 .

3D structure databases

ProteinModelPortali Q91280.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GT1. Glycosyltransferase Family 1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG004033.

Family and domain databases

InterProi IPR002213. UDP_glucos_trans.
[Graphical view ]
PANTHERi PTHR11926. PTHR11926. 1 hit.
Pfami PF00201. UDPGT. 1 hit.
[Graphical view ]
PROSITEi PS00375. UDPGT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning of the major 3-MC inducible phase I and phase II detoxification enzymes of plaice liver."
    Pirrit L., Healey R., Assheton H., Leaver M.J., George S.G.
    Mar. Environ. Res. 39:15-19(1995)
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Liver.

Entry informationi

Entry nameiUGT3_PLEPL
AccessioniPrimary (citable) accession number: Q91280
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: October 29, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3