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Protein
Submitted name:

Proopiomelanocortin

Gene

POMC

Organism
Petromyzon marinus (Sea lamprey)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
ProopiomelanocortinImported
Gene namesi
Name:POMCImported
OrganismiPetromyzon marinus (Sea lamprey)Imported
Taxonomic identifieri7757 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataCyclostomataHyperoartiaPetromyzontiformesPetromyzontidaePetromyzon

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence analysisAdd
BLAST
Chaini24 – 277254Sequence analysisPRO_5004319225Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi7757.ENSPMAP00000005352.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini246 – 27631Op_neuropeptideInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410Z5R4. LUCA.
HOVERGENiHBG073976.

Family and domain databases

InterProiIPR013532. Opioid_neuropept.
[Graphical view]
PfamiPF08035. Op_neuropeptide. 1 hit.
[Graphical view]
SMARTiSM01365. Op_neuropeptide. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91256-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGNCSRLLLL LEMLSIISPS ASAMCWARLD QGCFTDCKKY CSNGTRAGTP
60 70 80 90 100
AAVLENLLAC VQLKCSDDGD DNDDDAPLLQ WIASRAESRS DFDIANNKWW
110 120 130 140 150
LVRWGGQSGL SGEGGESGGS PRVEQVDLAG QVESSPASSS SQAKRSVSSP
160 170 180 190 200
KYAMGHFRWG SPDKATIRKR RPVRPNTSDS PEIPDYAFNG VEGPADDAGD
210 220 230 240 250
SVFMSRRETP DAAGHRGVDE AAATGEDAEV GNKDGVFRVP PPFKRYGGFM
260 270
KVMQEIDHWP LVPVIRKVMH KESTKSL
Length:277
Mass (Da):30,026
Last modified:November 1, 1996 - v1
Checksum:iFC4CDAB5F2C156B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U30886 mRNA. Translation: AAC59724.1.
PIRiI51117.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U30886 mRNA. Translation: AAC59724.1.
PIRiI51117.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7757.ENSPMAP00000005352.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiENOG410Z5R4. LUCA.
HOVERGENiHBG073976.

Family and domain databases

InterProiIPR013532. Opioid_neuropept.
[Graphical view]
PfamiPF08035. Op_neuropeptide. 1 hit.
[Graphical view]
SMARTiSM01365. Op_neuropeptide. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The appearance of proopiomelanocortin early in vertebrate evolution: cloning and sequencing of POMC from a Lamprey pituitary cDNA library."
    Heinig J.A., Keeley F.W., Robson P., Sower S.A., Youson J.H.
    Gen. Comp. Endocrinol. 99:137-144(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: PituitariesImported.

Entry informationi

Entry nameiQ91256_PETMA
AccessioniPrimary (citable) accession number: Q91256
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 8, 2016
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.