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Protein
Submitted name:

Prospero-related homeodomain protein 1

Gene

prox1a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • forebrain neuron development Source: ZFIN
  • lymphangiogenesis Source: ZFIN
  • myofibril assembly Source: ZFIN
  • negative regulation of sequence-specific DNA binding transcription factor activity Source: ZFIN
  • neuromast deposition Source: ZFIN
  • neuromast hair cell differentiation Source: ZFIN

Names & Taxonomyi

Protein namesi
Submitted name:
Prospero-related homeodomain protein 1Imported
Gene namesi
Name:prox1aImported
Synonyms:prox1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-980526-397. prox1a.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: ZFIN

PTM / Processingi

Proteomic databases

PaxDbiQ90ZL7.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000071943.

Structurei

3D structure databases

ProteinModelPortaliQ90ZL7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini579 – 737ProsperoInterPro annotationAdd BLAST159

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili229 – 256Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, HomeoboxImported

Phylogenomic databases

eggNOGiKOG3779. Eukaryota.
ENOG410ZE21. LUCA.
HOVERGENiHBG053693.
KOiK20211.

Family and domain databases

Gene3Di1.10.10.500. 1 hit.
InterProiView protein in InterPro
IPR023082. Homeo_prospero_dom.
IPR009057. Homeobox-like.
IPR007738. Prox1.
PANTHERiPTHR12198:SF10. PTHR12198:SF10. 1 hit.
PfamiView protein in Pfam
PF05044. HPD. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS51818. HOMEO_PROSPERO. 1 hit.

Sequencei

Sequence statusi: Complete.

Q90ZL7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPDHDSTSLL SRQTKRRRVD IGVKRTVGQA SVVFTRAKAT FLSAMNPHGS
60 70 80 90 100
EQDVECSVVQ HADGEKSNVL RKLLKRANSY EDAVMPFPGA TIISQLLKNN
110 120 130 140 150
LTKNGGSEPN FQGSGLSSTG SEMQQEDACS NSSRGSPQEC LSPFSRPSMT
160 170 180 190 200
QFEMERLTDE HLRAKRARVE NIIRGMSHSP SVTLRAGDND REGAAQPPSP
210 220 230 240 250
RENYRENKRK QKLPQQQQQS FQQLVSARKE QKHEERRQLK LQLEDMQKQL
260 270 280 290 300
RQLQEKFYQI YDSTDSENDE DGNLSEDSMR SDGMDNRAHD SVPDRSDNEM
310 320 330 340 350
SDLDPGHFLD RARALIREQS MMEGDKPKRD GSRGKSQGPT SMHAEGKQLA
360 370 380 390 400
ETLKQELNTA MSQVVDTVVK VFAKPPRPVP QVFPPLHMES PDRFAVNGEN
410 420 430 440 450
PNFHTANQRL QCFGDVIIPN PLDTFGSMQV PNSNDQTEAL PLVVRKNSSD
460 470 480 490 500
QTGSLSTPGG HHHHPSLHPP PLSSTMGFSP PSFRHPFPLP LMGYPFQSPL
510 520 530 540 550
GAPTGPYPGK DRSSPESLDL SRETTSLRTK MSSNHLSHHR SISPTHPGNE
560 570 580 590 600
GLSLSLIKSE CGDLQDMSDI SPYSGSTIQE GLSPNHLKKA KLMFFYTRYP
610 620 630 640 650
SSNMLKMFFS DVKFNRCITS QLIKWFSNFR EFYYIQMEKF ARQAINDGVT
660 670 680 690 700
GSEELSVSRD CELFRALNMH YNKANDFEVP ERFLEVAQIT LREFFNAIVA
710 720 730
GKDVDPSWKK AIYKVICKLD SEVPEIFKSP NCLQELLHE
Length:739
Mass (Da):83,214
Last modified:December 1, 2001 - v1
Checksum:iB01AC5910ADB6CA6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY032595 mRNA. Translation: AAK40357.1.
RefSeqiNP_571480.2. NM_131405.2.
UniGeneiDr.81273.

Genome annotation databases

GeneIDi30679.
KEGGidre:30679.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY032595 mRNA. Translation: AAK40357.1.
RefSeqiNP_571480.2. NM_131405.2.
UniGeneiDr.81273.

3D structure databases

ProteinModelPortaliQ90ZL7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000071943.

Proteomic databases

PaxDbiQ90ZL7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi30679.
KEGGidre:30679.

Organism-specific databases

CTDi30679.
ZFINiZDB-GENE-980526-397. prox1a.

Phylogenomic databases

eggNOGiKOG3779. Eukaryota.
ENOG410ZE21. LUCA.
HOVERGENiHBG053693.
KOiK20211.

Family and domain databases

Gene3Di1.10.10.500. 1 hit.
InterProiView protein in InterPro
IPR023082. Homeo_prospero_dom.
IPR009057. Homeobox-like.
IPR007738. Prox1.
PANTHERiPTHR12198:SF10. PTHR12198:SF10. 1 hit.
PfamiView protein in Pfam
PF05044. HPD. 1 hit.
SUPFAMiSSF46689. SSF46689. 1 hit.
PROSITEiView protein in PROSITE
PS51818. HOMEO_PROSPERO. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ90ZL7_DANRE
AccessioniPrimary (citable) accession number: Q90ZL7
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: June 7, 2017
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.