Q90ZB2 (Q90ZB2_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Gastrulation brain homeobox 1 EMBL AAI62948.1 Ensembl ENSDARP00000096349

Submitted name:
Transcription factor Gbx1 EMBL AAK83070.1

Gene names

Name:

gbx1 ZFIN ZDB-GENE-020117-2 Ensembl ENSDARP00000096349 EMBL AAK83070.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL AAK83070.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	316 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location

Nucleus By similarity RuleBase RU000682.

Ontologies

Keywords
Cellular component	Nucleus RuleBase RU000682
Domain	Homeobox RuleBase RU000682 EMBL AAI62948.1
Ligand	DNA-binding RuleBase RU000682
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	midbrain-hindbrain boundary morphogenesis Inferred from mutant phenotype. Source: ZFIN regulation of canonical Wnt receptor signaling pathway involved in neural plate anterior/posterior pattern formation Inferred from genetic interaction. Source: ZFIN
Cellular component	nucleus Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	sequence-specific DNA binding Inferred from electronic annotation. Source: InterPro sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q90ZB2 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: DC32955EA5430D8A	FASTA	316	34,409
	10 20 30 40 50 60 MQRPSGTGTA FSIDSLIGTP QPRPGHLLYT GYPMFMPYRP LMIPQALSHS SLPSGIPPLA 70 80 90 100 110 120 PLASFAGRLT NTFCAGLGQG MPSMVALTTT LPSFSDPPDS FYPPQEMPGP RLGADGTGMN 130 140 150 160 170 180 RQESPHDELK GSELLNFTET FQAVAGETKL YSSDDEKLDL KAAEAACSDR EDSSADSENE 190 200 210 220 230 240 SFSDGNTCAS ASQKGKLKGG SQDALPPGGS AGKSRRRRTA FTSEQLLELE KEFHCKKYLS 250 260 270 280 290 300 LTERSQIAHA LKLSEVQVKI WFQNRRAKWK RIKAGNVNNR SGEPVRNPKI VVPIPVHVNR 310 FAVRSQHQQI EPGSRP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning, expression and relationship of zebrafish gbx1 and gbx2 genes to Fgf signaling." Rhinn M., Lun K., Amores A., Yan Y.L., Postlethwait J.H., Brand M. Mech. Dev. 120:919-936(2003) [PubMed: 12963112] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Pooled EMBL AAI62948.1.
[3]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000096349.
[4]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000096349.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CT583690 Genomic DNA. No translation available. BC162948 mRNA. Translation: AAI62948.1. BC162949 mRNA. Translation: AAI62949.1. AF288763 mRNA. Translation: AAK83070.1.
IPI	IPI00506443.
RefSeq	NP_777286.1. NM_174861.2.
UniGene	Dr.81466.
3D structure databases
HSSP	HSSP built from PDB template 1B72 based on UniProtKB P14653.
ProteinModelPortal	Q90ZB2.
SMR	Q90ZB2. Positions 216-271.
ModBase	Search...
Protein-protein interaction databases
STRING	Q90ZB2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000105572; ENSDARP00000096349; ENSDARG00000071418.
GeneID	142985.
KEGG	dre:142985.
Organism-specific databases
CTD	2636.
ZFIN	ZDB-GENE-020117-2. gbx1.
Phylogenomic databases
eggNOG	fiNOG09422.
GeneTree	ENSGT00550000074296.
HOGENOM	HBG713875.
HOVERGEN	HBG003967.
InParanoid	Q90ZB2.
OMA	EEKLDAP.
OrthoDB	EOG4N5VXB.
PhylomeDB	Q90ZB2.
Gene expression databases
ArrayExpress	Q90ZB2.
Bgee	Q90ZB2.
Family and domain databases
InterPro	IPR001356. Homeobox. IPR017970. Homeobox_CS. IPR020479. Homeobox_eu. IPR009057. Homeodomain-like. IPR012287. Homeodomain-rel. [Graphical view]
Gene3D	G3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
KO	K09321.
Pfam	PF00046. Homeobox. 1 hit. [Graphical view]
PRINTS	PR00024. HOMEOBOX.
SMART	SM00389. HOX. 1 hit. [Graphical view]
SUPFAM	SSF46689. Homeodomain_like. 1 hit.
PROSITE	PS00027. HOMEOBOX_1. 1 hit. PS50071. HOMEOBOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q90ZB2_DANRE

Accession

Primary (citable) accession number: Q90ZB2

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	January 25, 2012
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)