Q90Z52 (Q90Z52_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glypican Knypek EMBL AAK69693.1

Gene names

Name:	gpc4 ZFIN ZDB-GENE-011119-1
Synonyms:	kny EMBL AAK69693.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL AAK69693.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	557 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Cell surface proteoglycan that bears heparan sulfate By similarity. RuleBase RU003519
Subcellular location	Cell membrane; Lipid-anchor › GPI-anchor By similarity RuleBase RU003519.
Sequence similarities	Belongs to the glypican family. RuleBase RU003518

Ontologies

Keywords
Cellular component	Membrane
PTM	GPI-anchor RuleBase RU003519 Glycoprotein Heparan sulfate RuleBase RU003519 Lipoprotein Proteoglycan
Gene Ontology (GO)
Biological process	convergent extension involved in gastrulation Inferred from genetic interaction. Source: UniProtKB eye development Inferred from genetic interaction. Source: UniProtKB somitogenesis Inferred from genetic interaction. Source: UniProtKB
Cellular component	anchored to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell proteinaceous extracellular matrix Inferred from electronic annotation. Source: InterPro
Molecular function	heparan sulfate proteoglycan binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q90Z52 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: B36A6ABCB6BCB1E8	FASTA	557	62,237
	10 20 30 40 50 60 MKMIVVFTVC MSVVVLASAQ ADQKSKNCNE VRTAYSSKGF NVNDVPNKGV QGAHLKVCPQ 70 80 90 100 110 120 GFSCCTLEME EKLSQLSRVD LKVPVHQLSS NLQSTFTQRH RHFDQFFREL LDNAEKSLNH 130 140 150 160 170 180 MFVRTYGLMY VKNKELFEGF FSDLRRYYSH GSSEVNLDDM LAEFWSELLE RMFRLVNVQY 190 200 210 220 230 240 EFSDSYMECV SRHTDQLKPF GDVPRKLRLQ LTRSFIAVRA FTRGLTLMPD VVRKVSTVSA 250 260 270 280 290 300 SPSCVRASMK MLYCPYCSGQ VALKPCKNYC LNVMRGCLAN QADLDTEWNN FLDSMLGLAE 310 320 330 340 350 360 RLEGPFNFES VVDPIDVKIS DAIMNMQENS MQVSQKVFQG CGQPKLSMGF RSRRSAKDSG 370 380 390 400 410 420 FPGRFRPYSP EARPTTAAGT TLDRLLTDVK KKLKHAKKFW STLPDTVCVG ERIAPSDDCW 430 440 450 460 470 480 NGTAKSRYES VVMSSGLANQ VSNPDVEVDI TKPDMVIRRQ IAVLKEMTSW LKAAYTGNDI 490 500 510 520 530 540 SFTSDDAGSG EESGSGCDSP SCEGDGDIYF STPAPGKPRI LKTQEVEQAS SGTRLAPCSL 550 ALALASLLLT LLTLQTR

References

[1]

"The zebrafish glypican knypek controls cell polarity during gastrulation movements of convergent extension." Topczewski J., Sepich D.S., Myers D.C., Walker C., Amores A., Lele Z., Hammerschmidt M., Postlethwait J., Solnica-Krezel L. Dev. Cell 1:251-264(2001) [PubMed: 11702784] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF354754 Genomic DNA. Translation: AAK69693.1.
IPI	IPI00495453.
UniGene	Dr.78935.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q90Z52.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	fiNOG08208.
GeneTree	ENSGT00550000074430.
HOVERGEN	HBG003464.
InParanoid	Q90Z52.
Gene expression databases
ArrayExpress	Q90Z52.
Bgee	Q90Z52.
Family and domain databases
InterPro	IPR001863. Glypican. [Graphical view]
PANTHER	PTHR10822. Glypican. 1 hit.
Pfam	PF01153. Glypican. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q90Z52_DANRE

Accession

Primary (citable) accession number: Q90Z52

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	October 19, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)