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Protein

60S ribosomal protein L13

Gene

rpl13

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • regulation of cell cycle Source: ZFIN
  • translation Source: GO_Central
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-DRE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DRE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DRE-6791226. Major pathway of rRNA processing in the nucleolus.
R-DRE-72689. Formation of a pool of free 40S subunits.
R-DRE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DRE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DRE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L13
Gene namesi
Name:rpl13
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 7

Organism-specific databases

ZFINiZDB-GENE-031007-1. rpl13.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 21121060S ribosomal protein L13PRO_0000192923Add
BLAST

Proteomic databases

PaxDbiQ90Z10.
PRIDEiQ90Z10.

Expressioni

Gene expression databases

BgeeiQ90Z10.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000047390.

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L13e family.Curated

Phylogenomic databases

eggNOGiKOG3295. Eukaryota.
COG4352. LUCA.
GeneTreeiENSGT00390000007818.
HOGENOMiHOG000170452.
HOVERGENiHBG001156.
InParanoidiQ90Z10.
KOiK02873.
OMAiHCPTFRY.
OrthoDBiEOG74TX1G.
PhylomeDBiQ90Z10.
TreeFamiTF300073.

Family and domain databases

InterProiIPR001380. Ribosomal_L13e.
IPR018256. Ribosomal_L13e_CS.
[Graphical view]
PANTHERiPTHR11722. PTHR11722. 1 hit.
PfamiPF01294. Ribosomal_L13e. 1 hit.
[Graphical view]
PROSITEiPS01104. RIBOSOMAL_L13E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q90Z10-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPSRNGMIL NPHFHKDWQK RVRTWFNQPA RKIRRRKARQ AKARRIAPRP
60 70 80 90 100
VSGPLRPVVR CPTIRYHTKV RAGRGFTLEE LKAAGINKKV ARTIGISVDS
110 120 130 140 150
RRRNRSTESL QANVQRLKEY RTKLIIFPRK AAKPKKGDST EEELKMATQL
160 170 180 190 200
TGPVMPIKKV HKKEKARVIS EDEKNFKAFA SLRMARANAR LFGIRAKRAK
210
EAAEQDVEKK K
Length:211
Mass (Da):24,365
Last modified:January 23, 2007 - v3
Checksum:iE32706629A5A94E6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF385081 mRNA. Translation: AAK63073.1.
AY561516 mRNA. Translation: AAS66969.1.
BC075977 mRNA. Translation: AAH75977.1.
RefSeqiNP_937786.1. NM_198143.1.
XP_005166723.1. XM_005166666.2.
UniGeneiDr.75569.

Genome annotation databases

EnsembliENSDART00000168460; ENSDARP00000132139; ENSDARG00000099380.
GeneIDi378961.
KEGGidre:378961.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF385081 mRNA. Translation: AAK63073.1.
AY561516 mRNA. Translation: AAS66969.1.
BC075977 mRNA. Translation: AAH75977.1.
RefSeqiNP_937786.1. NM_198143.1.
XP_005166723.1. XM_005166666.2.
UniGeneiDr.75569.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000047390.

Proteomic databases

PaxDbiQ90Z10.
PRIDEiQ90Z10.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000168460; ENSDARP00000132139; ENSDARG00000099380.
GeneIDi378961.
KEGGidre:378961.

Organism-specific databases

CTDi6137.
ZFINiZDB-GENE-031007-1. rpl13.

Phylogenomic databases

eggNOGiKOG3295. Eukaryota.
COG4352. LUCA.
GeneTreeiENSGT00390000007818.
HOGENOMiHOG000170452.
HOVERGENiHBG001156.
InParanoidiQ90Z10.
KOiK02873.
OMAiHCPTFRY.
OrthoDBiEOG74TX1G.
PhylomeDBiQ90Z10.
TreeFamiTF300073.

Enzyme and pathway databases

ReactomeiR-DRE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-DRE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-DRE-6791226. Major pathway of rRNA processing in the nucleolus.
R-DRE-72689. Formation of a pool of free 40S subunits.
R-DRE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-DRE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-DRE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiQ90Z10.

Gene expression databases

BgeeiQ90Z10.

Family and domain databases

InterProiIPR001380. Ribosomal_L13e.
IPR018256. Ribosomal_L13e_CS.
[Graphical view]
PANTHERiPTHR11722. PTHR11722. 1 hit.
PfamiPF01294. Ribosomal_L13e. 1 hit.
[Graphical view]
PROSITEiPS01104. RIBOSOMAL_L13E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular cloning of the zebrafish 60S ribosomal protein L13 (Breast basic conserved protein 1 homolog)."
    Miller V.M., Rebagliati M.R., Paulson H.L.
    Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "Many ribosomal protein genes are cancer genes in zebrafish."
    Amsterdam A., Sadler K.C., Lai K., Farrington S., Bronson R.T., Lees J.A., Hopkins N.
    PLoS Biol. 2:690-698(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  3. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiRL13_DANRE
AccessioniPrimary (citable) accession number: Q90Z10
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 11, 2002
Last sequence update: January 23, 2007
Last modified: July 6, 2016
This is version 82 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.