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Protein
Submitted name:

Cell adhesion molecule PCAM

Gene

ncam1b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  • axon guidance Source: ZFIN
  • cell adhesion Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cell adhesion molecule PCAMImported
Submitted name:
Neural cell adhesion molecule 3Imported
Submitted name:
PCAMImported
Gene namesi
Name:ncam1bImported
Synonyms:ncam3Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-010822-2. ncam1b.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei717 – 74024HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 10311012Sequence analysisPRO_5007324431Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000114314.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini3 – 108106Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini115 – 20288Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini209 – 29587Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini302 – 405104Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini410 – 49889Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini504 – 60198Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini604 – 70097Fibronectin type-IIIInterPro annotationAdd
BLAST

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3510. Eukaryota.
ENOG410XPX0. LUCA.
HOGENOMiHOG000074124.
HOVERGENiHBG052579.
KOiK06491.

Family and domain databases

Gene3Di2.60.40.10. 7 hits.
InterProiIPR003961. FN3_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR009138. Neural_cell_adh.
[Graphical view]
PfamiPF00041. fn3. 2 hits.
PF07679. I-set. 3 hits.
[Graphical view]
PRINTSiPR01838. NCAMFAMILY.
SMARTiSM00060. FN3. 2 hits.
SM00409. IG. 5 hits.
SM00408. IGc2. 5 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 5 hits.
SSF49265. SSF49265. 1 hit.
PROSITEiPS50853. FN3. 2 hits.
PS50835. IG_LIKE. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q90YM2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFPTKAIILV LLFFDNAVSL QVDITPAHGE ISVGESRFFL CEVIGGAKEI
60 70 80 90 100
DWFAPAGEKI EPGRPDISVI RNDETSSTLT IYNAKVDNAG TYRCVASSGD
110 120 130 140 150
QDAEATVNLK IYQKITFTNV PSPQEFTEGD NAIIVCDVIS SPPPTVLWKY
160 170 180 190 200
KGAKIQFDKD VRFKTLSNNH LQIRGIRKTD EGVYTCEGRI KARGEVDFRS
210 220 230 240 250
IKVVVNVLPT IRIRQAETNA TADMGFSTLL ACDPDGFPEP IVTWRRNNAP
260 270 280 290 300
LESGNKYSFN EDGSEMTVLD VTKLDEGDYT CIAKNKAGES EQELSLKVFV
310 320 330 340 350
QPKITYLESQ TTTEMDEQVT LTCEATGDPT PTITWSFGTR VFTEGEQASW
360 370 380 390 400
TRPEQHKGPD GEVLVRSDAR VSSLTLKYPQ YTDAGQYLCT ARNAIGETVQ
410 420 430 440 450
PVSLEVRYAP KILGSVAVYT WEGNPANISC EVLAHPSDVS ITWLRDGFQL
460 470 480 490 500
PNANTSNIKI HNTPSASYLE VNPESQSDFG NYNCTASNEI GTESREFIMI
510 520 530 540 550
PADVPSAPSI GEVQPYSSTA QVLFEEPEST GGVPVLKYRA EWRAVGRGKW
560 570 580 590 600
VQRVYEVKDG LSSVTVTGLK PETDYEVKMS AINGKGEGDS SPSMVFKTEH
610 620 630 640 650
VQGEPSPPIL EGTLQPKGNS LKVKWIKQDD GGSPITHYLV RYKAREDSEW
660 670 680 690 700
KPEIRLPSGS EYVMLIGLDW DTEYDVFVVA ENQQGKSKPG TLTFRTSSEP
710 720 730 740 750
TATTDSMEDG PGLNTGVIVG ILILVCVLLL LIVDATCCFL NKCGILMCIC
760 770 780 790 800
GKPGQSTKGK DIETGKAAFV QDVSKEPIVE VRTEEEATAN HDAEGHLEPN
810 820 830 840 850
ETTPLTEPEQ VTETAAAVVD LPLSVPTNSD TITDTFDLSQ SSPVSESTTL
860 870 880 890 900
TSSITAPPSD PINPVHMTPP DSSTPKTHSR PSISSSDPAN VTLLVDLAEV
910 920 930 940 950
SPAVPSEEPV QVPSSPTSVD HPGTIISKVT ENESVQSPSH AALNPISPQG
960 970 980 990 1000
DIAVPLVNHE LEIDGELPLA SDTDATQDGS HAGGTAGSSG PSAPAQDEKI
1010 1020 1030
LEDENAELKK VAPDAGFEPN AVTQTNIESK A
Length:1,031
Mass (Da):111,423
Last modified:December 1, 2001 - v1
Checksum:iC53F7DA51768C580
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC162073 mRNA. Translation: AAI62073.1.
AY029401 mRNA. Translation: AAK38466.1.
HM467819 mRNA. Translation: ADV36249.1.
RefSeqiNP_571906.1. NM_131831.1.
UniGeneiDr.12600.

Genome annotation databases

GeneIDi114442.
KEGGidre:114442.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC162073 mRNA. Translation: AAI62073.1.
AY029401 mRNA. Translation: AAK38466.1.
HM467819 mRNA. Translation: ADV36249.1.
RefSeqiNP_571906.1. NM_131831.1.
UniGeneiDr.12600.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000114314.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi114442.
KEGGidre:114442.

Organism-specific databases

CTDi114442.
ZFINiZDB-GENE-010822-2. ncam1b.

Phylogenomic databases

eggNOGiKOG3510. Eukaryota.
ENOG410XPX0. LUCA.
HOGENOMiHOG000074124.
HOVERGENiHBG052579.
KOiK06491.

Family and domain databases

Gene3Di2.60.40.10. 7 hits.
InterProiIPR003961. FN3_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR009138. Neural_cell_adh.
[Graphical view]
PfamiPF00041. fn3. 2 hits.
PF07679. I-set. 3 hits.
[Graphical view]
PRINTSiPR01838. NCAMFAMILY.
SMARTiSM00060. FN3. 2 hits.
SM00409. IG. 5 hits.
SM00408. IGc2. 5 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 5 hits.
SSF49265. SSF49265. 1 hit.
PROSITEiPS50853. FN3. 2 hits.
PS50835. IG_LIKE. 5 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular diversity in zebrafish NCAM family: three members with different VASE usage and distinct localization."
    Mizuno T., Kawasaki M., Nakahira M., Kagamiyama H., Kikuchi Y., Okamoto H., Mori K., Yoshihara Y.
    Mol. Cell. Neurosci. 18:119-130(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
  2. NIH - Zebrafish Gene Collection (ZGC) project
    Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  3. "Ncam1a and Ncam1b: two carriers of polysialic acid with different functions in the developing zebrafish nervous system."
    Langhauser M., Ustinova J., Rivera-Milla E., Ivannikov D., Seidl C., Slomka C., Finne J., Yoshihara Y., Bastmeyer M., Bentrop J.
    Glycobiology 22:196-209(2012) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ90YM2_DANRE
AccessioniPrimary (citable) accession number: Q90YM2
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: June 8, 2016
This is version 114 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.