Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cell adhesion molecule NCAM

Gene

ncam1a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • cell adhesion Source: InterPro
  • posterior commissure morphogenesis Source: ZFIN
  • regulation of synaptic plasticity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Cell adhesion molecule NCAMImported
Gene namesi
Name:ncam1aImported
Synonyms:ncam1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-990415-31. ncam1a.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei701 – 72424HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1919Sequence analysisAdd
BLAST
Chaini20 – 838819Sequence analysisPRO_5004318763Add
BLAST

Proteomic databases

PaxDbiQ90YM1.
PRIDEiQ90YM1.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
muskQ5J1R93EBI-1579680,EBI-1579627

Protein-protein interaction databases

IntActiQ90YM1. 1 interaction.
STRINGi7955.ENSDARP00000017613.

Structurei

3D structure databases

ProteinModelPortaliQ90YM1.
SMRiQ90YM1. Positions 20-205, 488-683.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 10485Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini106 – 18681Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini209 – 29789Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini302 – 39594Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini400 – 48990Ig-like (immunoglobulin-like)InterPro annotationAdd
BLAST
Domaini493 – 58997Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini591 – 68797Fibronectin type-IIIInterPro annotationAdd
BLAST

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IQJI. Eukaryota.
ENOG410XTGB. LUCA.
HOGENOMiHOG000074124.
HOVERGENiHBG052579.
PhylomeDBiQ90YM1.

Family and domain databases

Gene3Di2.60.40.10. 7 hits.
InterProiIPR003961. FN3_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR033019. Ncam1.
IPR009138. Neural_cell_adh.
[Graphical view]
PANTHERiPTHR10489:SF34. PTHR10489:SF34. 1 hit.
PfamiPF00041. fn3. 2 hits.
PF07679. I-set. 4 hits.
[Graphical view]
PRINTSiPR01838. NCAMFAMILY.
SMARTiSM00060. FN3. 2 hits.
SM00409. IG. 5 hits.
SM00408. IGc2. 5 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 5 hits.
SSF49265. SSF49265. 1 hit.
PROSITEiPS50853. FN3. 2 hits.
PS50835. IG_LIKE. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q90YM1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLQIRDLIWT LLFLGYAAAL QVEITPTQGE ISVGESKFFL CEVVGDAKEI
60 70 80 90 100
DWFAPNGEKL LPGRPDISIS KTDESSSTLT IYNANVDHAG MYKCVAKSGE
110 120 130 140 150
KEFRAPFIVK IFQKLTFQYA PSPQEFKEGD DADIICDVIS SPPPTIIWRY
160 170 180 190 200
KKMRIQPETD VRLKVLSNNH LQIRGIKKTD EGDYTCEGRI MARGEIDLRV
210 220 230 240 250
IKVIVNVLPS IRTRYTELNA TADINQAVTL ACHADGYPEP TVKWARGNTE
260 270 280 290 300
LESDEKYSLN EDGSELTIKD VNKLDEGDYK CIARNKAGER SEEVTLNVFV
310 320 330 340 350
QPKITFLENQ TASELEEQIT LTCEATGDPT PNIIWSFGRR VFTENEQSLD
360 370 380 390 400
GNVVVRSDAR VSSLTLKYVQ FTDAGQYLCT ARNSIGQDIQ SMYLEVRYAP
410 420 430 440 450
KIQGPQAVFT WEGNPANITC EALAHPGASV LWFRDGQQLP SANTTNVKIY
460 470 480 490 500
NTPTVSFLEV TPDSQNDFGS YNCTATNVIG TESKEFILVQ ADVPSAPSIE
510 520 530 540 550
RVEPYSSTAM IEFEEPASSG GVPVLKYKAE WRIAGQDWTD REYELEDGLN
560 570 580 590 600
LITIVGLKPE TTYEVKISAI NGKGEGESSA PESFKTQPVR EPNPPKLEAK
610 620 630 640 650
PQSTGNEMKV HFIKQDDGGS PIKHYLVRYR AKNRQDWKPE IRMPDASDYI
660 670 680 690 700
VLRGLDWNTE YEVYVIAENQ RGRSEPGTLS FRTLPEPTAI PETSSGLGTG
710 720 730 740 750
AIVGILIVVF ILLLFGVDVT CYFLNKCGLL MCIAVNFCGK SGPSAAKSKD
760 770 780 790 800
IEEGKAAFTK DESKEPIVEV RTEEERTPNH EGGGPTEPNE TTPLTDPDGK
810 820 830
IIVDDKSKAP ETEVKKPPAE VKTVPNEAPQ ANGNESKA
Length:838
Mass (Da):92,840
Last modified:December 1, 2001 - v1
Checksum:i9A8E9E3FFF98CAC6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY029402 mRNA. Translation: AAK38467.1.
UniGeneiDr.75350.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY029402 mRNA. Translation: AAK38467.1.
UniGeneiDr.75350.

3D structure databases

ProteinModelPortaliQ90YM1.
SMRiQ90YM1. Positions 20-205, 488-683.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ90YM1. 1 interaction.
STRINGi7955.ENSDARP00000017613.

Proteomic databases

PaxDbiQ90YM1.
PRIDEiQ90YM1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

ZFINiZDB-GENE-990415-31. ncam1a.

Phylogenomic databases

eggNOGiENOG410IQJI. Eukaryota.
ENOG410XTGB. LUCA.
HOGENOMiHOG000074124.
HOVERGENiHBG052579.
PhylomeDBiQ90YM1.

Family and domain databases

Gene3Di2.60.40.10. 7 hits.
InterProiIPR003961. FN3_dom.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR003598. Ig_sub2.
IPR033019. Ncam1.
IPR009138. Neural_cell_adh.
[Graphical view]
PANTHERiPTHR10489:SF34. PTHR10489:SF34. 1 hit.
PfamiPF00041. fn3. 2 hits.
PF07679. I-set. 4 hits.
[Graphical view]
PRINTSiPR01838. NCAMFAMILY.
SMARTiSM00060. FN3. 2 hits.
SM00409. IG. 5 hits.
SM00408. IGc2. 5 hits.
[Graphical view]
SUPFAMiSSF48726. SSF48726. 5 hits.
SSF49265. SSF49265. 1 hit.
PROSITEiPS50853. FN3. 2 hits.
PS50835. IG_LIKE. 5 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Molecular diversity in zebrafish NCAM family: three members with different VASE usage and distinct localization."
    Mizuno T., Kawasaki M., Nakahira M., Kagamiyama H., Kikuchi Y., Okamoto H., Mori K., Yoshihara Y.
    Mol. Cell. Neurosci. 18:119-130(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ90YM1_DANRE
AccessioniPrimary (citable) accession number: Q90YM1
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: May 11, 2016
This is version 109 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.