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Protein
Submitted name:

Claudin b

Gene

cldnb

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • neuromast development Source: ZFIN
  • regulation of sodium ion transport Source: ZFIN

Names & Taxonomyi

Protein namesi
Submitted name:
Claudin bImported
Submitted name:
Cldnb proteinImported
Gene namesi
Name:cldnbImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 21

Organism-specific databases

ZFINiZDB-GENE-010328-2 cldnb

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 27HelicalSequence analysisAdd BLAST22
Transmembranei79 – 99HelicalSequence analysisAdd BLAST21
Transmembranei119 – 141HelicalSequence analysisAdd BLAST23
Transmembranei162 – 181HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, Tight junctionSAAS annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000009544

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000013958

Family & Domainsi

Sequence similaritiesi

Belongs to the claudin family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiENOG410IIJR Eukaryota
ENOG410YA61 LUCA
GeneTreeiENSGT00760000118928
HOGENOMiHOG000220937
HOVERGENiHBG000643
KOiK06087
OMAiIVTSQIT
OrthoDBiEOG091G0MMR
TreeFamiTF331936

Family and domain databases

InterProiView protein in InterPro
IPR006187 Claudin
IPR004031 PMP22/EMP/MP20/Claudin
PANTHERiPTHR12002 PTHR12002, 1 hit
PfamiView protein in Pfam
PF00822 PMP22_Claudin, 1 hit

Sequencei

Sequence statusi: Complete.

Q90XR8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASTGLQMLG IALAIFGWIG VIVLCALPMW KVTAFIGANI VTSQTSWEGI
60 70 80 90 100
WMSCVVQSTG QMQCKVYDSM LALSSDIQAA RALTVISIVI GVMGIMLSMA
110 120 130 140 150
GGKCTNCIEE ESSKAKVGIT AGVIFIISGV LCLVPVCWTA NAIIQDFYNP
160 170 180 190 200
LVVQAQKREI GASLYIGWGA SALLIIGGSL LCCHCPEKSD SGKYTAKYNA
210
TPRSEASAPS GKNFV
Length:215
Mass (Da):22,656
Last modified:December 1, 2001 - v1
Checksum:iF3D944F527751145
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR847847 Genomic DNA No translation available.
BC078358 mRNA Translation: AAH78358.1
BC163985 mRNA Translation: AAI63985.1
AF359426 mRNA Translation: AAL01833.1
RefSeqiNP_571838.1, NM_131763.2
UniGeneiDr.76013

Genome annotation databases

EnsembliENSDART00000021664; ENSDARP00000013958; ENSDARG00000009544
GeneIDi81581
KEGGidre:81581

Similar proteinsi

Entry informationi

Entry nameiQ90XR8_DANRE
AccessioniPrimary (citable) accession number: Q90XR8
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: March 28, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health