Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q90XD2

- SPEB_CHICK

UniProt

Q90XD2 - SPEB_CHICK

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Agmatinase, mitochondrial

Gene

AGMAT

Organism
Gallus gallus (Chicken)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Agmatine + H2O = putrescine + urea.

Cofactori

Manganese.PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi150 – 1501Manganese 1PROSITE-ProRule annotation
Metal bindingi173 – 1731Manganese 1PROSITE-ProRule annotation
Metal bindingi173 – 1731Manganese 2PROSITE-ProRule annotation
Metal bindingi175 – 1751Manganese 2PROSITE-ProRule annotation
Metal bindingi177 – 1771Manganese 1PROSITE-ProRule annotation
Metal bindingi264 – 2641Manganese 1PROSITE-ProRule annotation
Metal bindingi264 – 2641Manganese 2PROSITE-ProRule annotation
Metal bindingi266 – 2661Manganese 2PROSITE-ProRule annotation

GO - Molecular functioni

  1. agmatinase activity Source: UniProtKB-EC
  2. metal ion binding Source: UniProtKB-KW

GO - Biological processi

  1. putrescine biosynthetic process from arginine Source: UniProtKB-UniPathway
  2. spermidine biosynthetic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Putrescine biosynthesis, Spermidine biosynthesis

Keywords - Ligandi

Manganese, Metal-binding

Enzyme and pathway databases

BioCyciRETL1328306-WGS:GSTH-2153-MONOMER.
UniPathwayiUPA00534; UER00287.

Names & Taxonomyi

Protein namesi
Recommended name:
Agmatinase, mitochondrial (EC:3.5.3.11)
Alternative name(s):
Agmatine ureohydrolase
Short name:
AUH
Gene namesi
Name:AGMAT
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalliformesPhasianidaePhasianinaeGallus
ProteomesiUP000000539: Chromosome 21

Subcellular locationi

Mitochondrion By similarity

GO - Cellular componenti

  1. extracellular vesicular exosome Source: Ensembl
  2. mitochondrion Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini? – 340Agmatinase, mitochondrialPRO_0000002090
Transit peptidei1 – ?MitochondrionSequence Analysis

Proteomic databases

PaxDbiQ90XD2.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000022199.

Structurei

3D structure databases

ProteinModelPortaliQ90XD2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the arginase family. Agmatinase subfamily.PROSITE-ProRule annotation

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG0010.
GeneTreeiENSGT00530000063082.
HOGENOMiHOG000204320.
HOVERGENiHBG023165.
InParanoidiQ90XD2.
KOiK01480.
OMAiSPPYDPF.
OrthoDBiEOG7M98GH.
PhylomeDBiQ90XD2.
TreeFamiTF328612.

Family and domain databases

Gene3Di3.40.800.10. 1 hit.
InterProiIPR005925. Agmatinase-rel.
IPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view]
PANTHERiPTHR11358. PTHR11358. 1 hit.
PfamiPF00491. Arginase. 1 hit.
[Graphical view]
PIRSFiPIRSF036979. Arginase. 1 hit.
PRINTSiPR00116. ARGINASE.
TIGRFAMsiTIGR01230. agmatinase. 1 hit.
PROSITEiPS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q90XD2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MICLLRTARL SARLLFASAA APCRRASRFN VPPSAEFVAR PVGVCSMLRL
60 70 80 90 100
PVQTSAEGLD AAFVGVPLDT GTSNRPGARF GPQQIRAESV MVRRYNASTG
110 120 130 140 150
AAPFDSLLVA DVGDVNVNLY NLPDSCRRIR ESYQKIVASG CVPLTLGGDH
160 170 180 190 200
SITYPILQAV AEKHGPVGLV HVDAHTDTSD MALGEKIYHG TPFRRCVDEG
210 220 230 240 250
LLDCSRVVQI GIRGSSYAPN PYKYCWDQGF RVVPAEECWM KSLVPLMGEV
260 270 280 290 300
RQQMGDGPVY ISFDIDGLDP AYAPGTGTPE IAGLTPMQAL EIIRGCKGLN
310 320 330 340
IVGCDLVEVA PIYDVSGNTA LLGANLLFEM LCVLPGVKTM
Length:340
Mass (Da):36,488
Last modified:December 1, 2001 - v1
Checksum:i305E113C32F75F89
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF401291 mRNA. Translation: AAK97629.1.
RefSeqiNP_989474.1. NM_204143.2.
UniGeneiGga.92.

Genome annotation databases

EnsembliENSGALT00000022238; ENSGALP00000022199; ENSGALG00000013678.
GeneIDi373942.
KEGGigga:373942.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF401291 mRNA. Translation: AAK97629.1 .
RefSeqi NP_989474.1. NM_204143.2.
UniGenei Gga.92.

3D structure databases

ProteinModelPortali Q90XD2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9031.ENSGALP00000022199.

Proteomic databases

PaxDbi Q90XD2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSGALT00000022238 ; ENSGALP00000022199 ; ENSGALG00000013678 .
GeneIDi 373942.
KEGGi gga:373942.

Organism-specific databases

CTDi 79814.

Phylogenomic databases

eggNOGi COG0010.
GeneTreei ENSGT00530000063082.
HOGENOMi HOG000204320.
HOVERGENi HBG023165.
InParanoidi Q90XD2.
KOi K01480.
OMAi SPPYDPF.
OrthoDBi EOG7M98GH.
PhylomeDBi Q90XD2.
TreeFami TF328612.

Enzyme and pathway databases

UniPathwayi UPA00534 ; UER00287 .
BioCyci RETL1328306-WGS:GSTH-2153-MONOMER.

Miscellaneous databases

NextBioi 20813474.
PROi Q90XD2.

Family and domain databases

Gene3Di 3.40.800.10. 1 hit.
InterProi IPR005925. Agmatinase-rel.
IPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
IPR020855. Ureohydrolase_Mn_BS.
[Graphical view ]
PANTHERi PTHR11358. PTHR11358. 1 hit.
Pfami PF00491. Arginase. 1 hit.
[Graphical view ]
PIRSFi PIRSF036979. Arginase. 1 hit.
PRINTSi PR00116. ARGINASE.
TIGRFAMsi TIGR01230. agmatinase. 1 hit.
PROSITEi PS01053. ARGINASE_1. 1 hit.
PS51409. ARGINASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Identification of chicken agmatinase."
    Morris S.M. Jr., Kepka-Lenhart D.
    Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Liver.

Entry informationi

Entry nameiSPEB_CHICK
AccessioniPrimary (citable) accession number: Q90XD2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: December 1, 2001
Last modified: October 29, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3