Reviewed,
UniProtKB/Swiss-Prot Q90XD2 (SPEB_CHICK)
Last modified
November 3, 2009.
Version 51.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Agmatinase, mitochondrial EC=3.5.3.11 Alternative name(s): Agmatine ureohydrolase Short name=AUH | ||
| Gene names |
| ||
| Organism | Gallus gallus (Chicken) | ||
| Taxonomic identifier | 9031 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus |
Protein attributes
| Sequence length | 340 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Catalytic activity | Agmatine + H2O = putrescine + urea. |
| Cofactor | Manganese Potential. |
| Pathway | |
| Subcellular location | Mitochondrion By similarity. |
| Sequence similarities | Belongs to the arginase family. Agmatinase subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Putrescine biosynthesis Spermidine biosynthesis |
| Cellular component | Mitochondrion |
| Domain | Transit peptide |
| Ligand | Manganese Metal-binding |
| Molecular function | Hydrolase |
| Gene Ontology (GO) | |
| Biological process | putrescine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW spermidine biosynthetic processInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | mitochondrion Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | agmatinase activity Inferred from electronic annotation. Source: EC manganese ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Transit peptide | 1 – ? | Mitochondrion Potential | |||||||
| Chain | ? – 340 | Agmatinase, mitochondrial | PRO_0000002090 | ||||||
Sites | |||||||||
| Metal binding | 150 | 1 | Manganese 1 By similarity | ||||||
| Metal binding | 173 | 1 | Manganese 1 By similarity | ||||||
| Metal binding | 173 | 1 | Manganese 2 By similarity | ||||||
| Metal binding | 175 | 1 | Manganese 2 By similarity | ||||||
| Metal binding | 177 | 1 | Manganese 1 By similarity | ||||||
| Metal binding | 264 | 1 | Manganese 1 By similarity | ||||||
| Metal binding | 264 | 1 | Manganese 2 By similarity | ||||||
| Metal binding | 266 | 1 | Manganese 2 By similarity | ||||||
Sequences
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References
| [1] | "Identification of chicken agmatinase." Morris S.M. Jr., Kepka-Lenhart D. Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Tissue: Liver. |
Cross-references
Sequence databases | |
|---|---|
| AF401291 mRNA. Translation: AAK97629.1. | |
| IPI | IPI00594724. |
| RefSeq | NP_989474.1. |
| UniGene | Gga.39549 |
3D structure databases | |
| HSSP | HSSP built from PDB template 1GQ6 based on UniProtKB P37819. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q90XD2. |
Genome annotation databases | |
| Ensembl | ENSGALT00000022238; ENSGALP00000022199; ENSGALG00000013678; Gallus gallus. [Genome view] |
| GeneID | 373942. |
| KEGG | gga:373942. |
Organism-specific databases | |
| CTD | 373942. |
Phylogenomic databases | |
| HOGENOM | Q90XD2. |
| HOVERGEN | Q90XD2. |
| OMA | FGAEYTH. |
Enzyme and pathway databases | |
| BRENDA | 3.5.3.11. 4. |
Family and domain databases | |
| InterPro | IPR005925. Agmatinase. IPR005924. Arginase. IPR006035. Ureohydrolase. [Graphical view] |
| Gene3D | G3DSA:3.40.800.10. Ureohydrolase. 1 hit. |
| PANTHER | PTHR11358. Ureohydrolase. 1 hit. |
| Pfam | PF00491. Arginase. 1 hit. [Graphical view] |
| PRINTS | PR00116. ARGINASE. |
| TIGRFAMs | TIGR01230. agmatinase. 1 hit. |
| PROSITE | PS01053. ARGINASE_1. 1 hit. PS51409. ARGINASE_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | SPEB_CHICK | ||||||||
| Accession | Primary (citable) accession number: Q90XD2 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with


