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Protein

Oligodendrocyte transcription factor 2

Gene

OLIG2

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Required for oligodendrocyte and motor neuron specification in the spinal cord.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Oligodendrocyte transcription factor 2
Short name:
Oligo2
Gene namesi
Name:OLIG2
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001274161 – 298Oligodendrocyte transcription factor 2Add BLAST298

Expressioni

Gene expression databases

BgeeiENSGALG00000027381

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ90XB3
SMRiQ90XB3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini106 – 160bHLHPROSITE-ProRule annotationAdd BLAST55

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi24 – 42Gly-richAdd BLAST19
Compositional biasi45 – 92Ser-richAdd BLAST48

Phylogenomic databases

GeneTreeiENSGT00530000063239
HOVERGENiHBG053370
InParanoidiQ90XB3
KOiK09085
OMAiSFQHWGG
OrthoDBiEOG091G129L
PhylomeDBiQ90XB3

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
IPR032658 Olig2
PANTHERiPTHR19290:SF32 PTHR19290:SF32, 1 hit
PfamiView protein in Pfam
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit

Sequencei

Sequence statusi: Complete.

Q90XB3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSDASLVSS RPSSPEPDEL FLAGRNKGGG GGGGGGGGFT GGTVSSSTQS
60 70 80 90 100
DSPPELSAEL RSAMSAAGVV VVDKLGFKSS SSSASSASSA SSKKDKKQMT
110 120 130 140 150
EPELQQLRLK INSRERKRMH DLNIAMDGLR EVMPYAHGPS VRKLSKIATL
160 170 180 190 200
LLARNYILML TNSLEEMKRL VSEIYGGHHA AFHPAACPAG MGAHSAPLPA
210 220 230 240 250
HPGHPASHPA HHPILPPAAV SSASLPGSGL SAVGSIRPPH GLLKSPSAAA
260 270 280 290
AAPGLGGGFQ HWGGMPCPCS MCQVAAPPHH HVSAMGGAAL PRLASDAK
Length:298
Mass (Da):30,319
Last modified:December 1, 2001 - v1
Checksum:i5790A79F2764F5D8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF411041 mRNA Translation: AAL11883.1
AF405699 mRNA Translation: AAL02428.1
RefSeqiNP_001026697.1, NM_001031526.1
UniGeneiGga.4947
Gga.51492

Genome annotation databases

EnsembliENSGALT00000049196; ENSGALP00000047462; ENSGALG00000031010
GeneIDi428612
KEGGigga:428612

Similar proteinsi

Entry informationi

Entry nameiOLIG2_CHICK
AccessioniPrimary (citable) accession number: Q90XB3
Secondary accession number(s): Q90XC8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2002
Last sequence update: December 1, 2001
Last modified: March 28, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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