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Protein
Submitted name:

Surfactant protein A

Gene

SP-A

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

ReactomeiR-GGA-166016. Toll Like Receptor 4 (TLR4) Cascade.
R-GGA-391160. Signal regulatory protein family interactions.
R-GGA-5683826. Surfactant metabolism.
R-GGA-5686938. Regulation of TLR by endogenous ligand.

Names & Taxonomyi

Protein namesi
Submitted name:
Surfactant protein AImported
Gene namesi
Name:SP-AImported
Synonyms:SFTPAImported
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 6

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501014731222 – 222Sequence analysisAdd BLAST201

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSGALG00000002503.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000003937.

Structurei

3D structure databases

SMRiQ90XB2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini121 – 221C-type lectinInterPro annotationAdd BLAST101

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IS27. Eukaryota.
ENOG410YK84. LUCA.
GeneTreeiENSGT00700000104102.
HOGENOMiHOG000085660.
HOVERGENiHBG108270.
KOiK10067.
OMAiCHAQNCA.
OrthoDBiEOG091G0PU5.
TreeFamiTF330481.

Family and domain databases

CDDicd03591. CLECT_collectin_like. 1 hit.
Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link.
IPR018378. C-type_lectin_CS.
IPR033990. Collectin_CTLD.
IPR016187. CTDL_fold.
PfamiView protein in Pfam
PF00059. Lectin_C. 1 hit.
SMARTiView protein in SMART
SM00034. CLECT. 1 hit.
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiView protein in PROSITE
PS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q90XB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSYSFCMIA AAVALLTPCH AQNCAGAPEL PSIPGVSGLL GLGALKRYFG
60 70 80 90 100
SLLWPYGEEK LPECQWLQRQ QDLSTSSDDE LGNVLLNLRQ RILQLEGVLA
110 120 130 140 150
LDGKITKVGE KIFASNGKEV NFSSALESCE ETGGTLATPM NEEENKAIMG
160 170 180 190 200
IVKQYNRYAY LGIKESDTAG QFKYVNNQPL NYTSWQQYEP NGKGTEKCVE
210 220
MYTDGNWKDR KCNLYRLTVC EY
Length:222
Mass (Da):24,721
Last modified:December 1, 2001 - v1
Checksum:i97371A3C53303872
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000143 Genomic DNA. No translation available.
AF411083 mRNA. Translation: AAK97540.1.
RefSeqiNP_989937.1. NM_204606.1.
XP_015143440.1. XM_015287954.1.
UniGeneiGga.936.

Genome annotation databases

EnsembliENSGALT00000003946; ENSGALP00000003937; ENSGALG00000002503.
GeneIDi395308.
KEGGigga:395308.

Similar proteinsi

Entry informationi

Entry nameiQ90XB2_CHICK
AccessioniPrimary (citable) accession number: Q90XB2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: September 27, 2017
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported