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Q90XB2

- Q90XB2_CHICK

UniProt

Q90XB2 - Q90XB2_CHICK

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Protein
Submitted name:

Surfactant protein A

Gene

SP-A

Organism
Gallus gallus (Chicken)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_239556. Signal regulatory protein (SIRP) family interactions.
REACT_241289. Toll Like Receptor 4 (TLR4) Cascade.

Names & Taxonomyi

Protein namesi
Submitted name:
Surfactant protein AImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:SP-AImported
Synonyms:SFTPA1Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiTestudines + Archosauria groupArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
ProteomesiUP000000539: Chromosome 6

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818 PotentialImportedAdd
BLAST
Chaini19 – 222204 PotentialImportedPRO_5000061299Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000003937.

Structurei

3D structure databases

ProteinModelPortaliQ90XB2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains C-type lectin domain.SAAS annotation

Keywords - Domaini

SignalImported

Phylogenomic databases

eggNOGiNOG315755.
GeneTreeiENSGT00700000104102.
HOGENOMiHOG000085660.
HOVERGENiHBG108270.
InParanoidiQ90XB2.
KOiK10067.
OMAiQYNRYAY.
OrthoDBiEOG7HXCVB.
PhylomeDBiQ90XB2.
TreeFamiTF330481.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR001304. C-type_lectin.
IPR016186. C-type_lectin-like.
IPR018378. C-type_lectin_CS.
IPR016187. C-type_lectin_fold.
[Graphical view]
PfamiPF00059. Lectin_C. 1 hit.
[Graphical view]
SMARTiSM00034. CLECT. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiPS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q90XB2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLSYSFCMIA AAVALLTPCH AQNCAGAPEL PSIPGVSGLL GLGALKRYFG
60 70 80 90 100
SLLWPYGEEK LPECQWLQRQ QDLSTSSDDE LGNVLLNLRQ RILQLEGVLA
110 120 130 140 150
LDGKITKVGE KIFASNGKEV NFSSALESCE ETGGTLATPM NEEENKAIMG
160 170 180 190 200
IVKQYNRYAY LGIKESDTAG QFKYVNNQPL NYTSWQQYEP NGKGTEKCVE
210 220
MYTDGNWKDR KCNLYRLTVC EY
Length:222
Mass (Da):24,721
Last modified:December 1, 2001 - v1
Checksum:i97371A3C53303872
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN03005176 Genomic DNA. No translation available.
AF411083 mRNA. Translation: AAK97540.1.
RefSeqiNP_989937.1. NM_204606.1.
UniGeneiGga.936.

Genome annotation databases

EnsembliENSGALT00000003946; ENSGALP00000003937; ENSGALG00000002503.
ENSGALT00000044265; ENSGALP00000042366; ENSGALG00000002503.
GeneIDi395308.
KEGGigga:395308.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN03005176 Genomic DNA. No translation available.
AF411083 mRNA. Translation: AAK97540.1 .
RefSeqi NP_989937.1. NM_204606.1.
UniGenei Gga.936.

3D structure databases

ProteinModelPortali Q90XB2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9031.ENSGALP00000003937.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSGALT00000003946 ; ENSGALP00000003937 ; ENSGALG00000002503 .
ENSGALT00000044265 ; ENSGALP00000042366 ; ENSGALG00000002503 .
GeneIDi 395308.
KEGGi gga:395308.

Organism-specific databases

CTDi 653509.

Phylogenomic databases

eggNOGi NOG315755.
GeneTreei ENSGT00700000104102.
HOGENOMi HOG000085660.
HOVERGENi HBG108270.
InParanoidi Q90XB2.
KOi K10067.
OMAi QYNRYAY.
OrthoDBi EOG7HXCVB.
PhylomeDBi Q90XB2.
TreeFami TF330481.

Enzyme and pathway databases

Reactomei REACT_239556. Signal regulatory protein (SIRP) family interactions.
REACT_241289. Toll Like Receptor 4 (TLR4) Cascade.

Miscellaneous databases

NextBioi 20815393.

Family and domain databases

Gene3Di 3.10.100.10. 1 hit.
InterProi IPR001304. C-type_lectin.
IPR016186. C-type_lectin-like.
IPR018378. C-type_lectin_CS.
IPR016187. C-type_lectin_fold.
[Graphical view ]
Pfami PF00059. Lectin_C. 1 hit.
[Graphical view ]
SMARTi SM00034. CLECT. 1 hit.
[Graphical view ]
SUPFAMi SSF56436. SSF56436. 1 hit.
PROSITEi PS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The chicken homolog of surfactant protein A has only three collagen-like Gly-Xaa-Yaa repeats and contain a new putative coil structure between the collagen region and the alpha-helical coil-coil region."
    Vitved L., Hansen S., Teisner B., Koch C., Juul-Madsen H., Holmskov U., Salomonsen J., Skjodt K.
    Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LungImported.
  2. "Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolution."
    International Chicken Genome Sequencing Consortium
    Hillier L.W., Miller W., Birney E., Warren W., Hardison R.C., Ponting C.P., Bork P., Burt D.W., Groenen M.A.M., Delany M.E., Dodgson J.B., Chinwalla A.T., Cliften P.F., Clifton S.W., Delehaunty K.D., Fronick C., Fulton R.S., Graves T.A.
    , Kremitzki C., Layman D., Magrini V., McPherson J.D., Miner T.L., Minx P., Nash W.E., Nhan M.N., Nelson J.O., Oddy L.G., Pohl C.S., Randall-Maher J., Smith S.M., Wallis J.W., Yang S.-P., Romanov M.N., Rondelli C.M., Paton B., Smith J., Morrice D., Daniels L., Tempest H.G., Robertson L., Masabanda J.S., Griffin D.K., Vignal A., Fillon V., Jacobbson L., Kerje S., Andersson L., Crooijmans R.P., Aerts J., van der Poel J.J., Ellegren H., Caldwell R.B., Hubbard S.J., Grafham D.V., Kierzek A.M., McLaren S.R., Overton I.M., Arakawa H., Beattie K.J., Bezzubov Y., Boardman P.E., Bonfield J.K., Croning M.D.R., Davies R.M., Francis M.D., Humphray S.J., Scott C.E., Taylor R.G., Tickle C., Brown W.R.A., Rogers J., Buerstedde J.-M., Wilson S.A., Stubbs L., Ovcharenko I., Gordon L., Lucas S., Miller M.M., Inoko H., Shiina T., Kaufman J., Salomonsen J., Skjoedt K., Wong G.K.-S., Wang J., Liu B., Wang J., Yu J., Yang H., Nefedov M., Koriabine M., Dejong P.J., Goodstadt L., Webber C., Dickens N.J., Letunic I., Suyama M., Torrents D., von Mering C., Zdobnov E.M., Makova K., Nekrutenko A., Elnitski L., Eswara P., King D.C., Yang S.-P., Tyekucheva S., Radakrishnan A., Harris R.S., Chiaromonte F., Taylor J., He J., Rijnkels M., Griffiths-Jones S., Ureta-Vidal A., Hoffman M.M., Severin J., Searle S.M.J., Law A.S., Speed D., Waddington D., Cheng Z., Tuzun E., Eichler E., Bao Z., Flicek P., Shteynberg D.D., Brent M.R., Bye J.M., Huckle E.J., Chatterji S., Dewey C., Pachter L., Kouranov A., Mourelatos Z., Hatzigeorgiou A.G., Paterson A.H., Ivarie R., Brandstrom M., Axelsson E., Backstrom N., Berlin S., Webster M.T., Pourquie O., Reymond A., Ucla C., Antonarakis S.E., Long M., Emerson J.J., Betran E., Dupanloup I., Kaessmann H., Hinrichs A.S., Bejerano G., Furey T.S., Harte R.A., Raney B., Siepel A., Kent W.J., Haussler D., Eyras E., Castelo R., Abril J.F., Castellano S., Camara F., Parra G., Guigo R., Bourque G., Tesler G., Pevzner P.A., Smit A., Fulton L.A., Mardis E.R., Wilson R.K.
    Nature 432:695-716(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Red jungle fowlImported.
  3. Ensembl
    Submitted (JUL-2011) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Red jungle fowlImported.
  4. Ensembl
    Submitted (MAY-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: Red jungle fowlImported.

Entry informationi

Entry nameiQ90XB2_CHICK
AccessioniPrimary (citable) accession number: Q90XB2
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: November 26, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3