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Protein
Submitted name:

Surfactant protein A

Gene

SP-A

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

ReactomeiR-GGA-166016 Toll Like Receptor 4 (TLR4) Cascade
R-GGA-5683826 Surfactant metabolism
R-GGA-5686938 Regulation of TLR by endogenous ligand

Names & Taxonomyi

Protein namesi
Submitted name:
Surfactant protein AImported
Gene namesi
Name:SP-AImported
Synonyms:SFTPAImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 6

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501431241522 – 222Sequence analysisAdd BLAST201

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSGALG00000002503

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000003937

Structurei

3D structure databases

SMRiQ90XB2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini121 – 221C-type lectinInterPro annotationAdd BLAST101

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IS27 Eukaryota
ENOG410YK84 LUCA
GeneTreeiENSGT00700000104102
HOGENOMiHOG000085660
HOVERGENiHBG108270
KOiK10067
OMAiCHAQNCA
OrthoDBiEOG091G0PU5
TreeFamiTF330481

Family and domain databases

CDDicd03591 CLECT_collectin_like, 1 hit
Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR001304 C-type_lectin-like
IPR016186 C-type_lectin-like/link_sf
IPR018378 C-type_lectin_CS
IPR033990 Collectin_CTLD
IPR016187 CTDL_fold
PfamiView protein in Pfam
PF00059 Lectin_C, 1 hit
SMARTiView protein in SMART
SM00034 CLECT, 1 hit
SUPFAMiSSF56436 SSF56436, 1 hit
PROSITEiView protein in PROSITE
PS00615 C_TYPE_LECTIN_1, 1 hit
PS50041 C_TYPE_LECTIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q90XB2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLSYSFCMIA AAVALLTPCH AQNCAGAPEL PSIPGVSGLL GLGALKRYFG
60 70 80 90 100
SLLWPYGEEK LPECQWLQRQ QDLSTSSDDE LGNVLLNLRQ RILQLEGVLA
110 120 130 140 150
LDGKITKVGE KIFASNGKEV NFSSALESCE ETGGTLATPM NEEENKAIMG
160 170 180 190 200
IVKQYNRYAY LGIKESDTAG QFKYVNNQPL NYTSWQQYEP NGKGTEKCVE
210 220
MYTDGNWKDR KCNLYRLTVC EY
Length:222
Mass (Da):24,721
Last modified:December 1, 2001 - v1
Checksum:i97371A3C53303872
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000143 Genomic DNA No translation available.
AF411083 mRNA Translation: AAK97540.1
RefSeqiNP_989937.1, NM_204606.1
XP_015143440.1, XM_015287954.1
UniGeneiGga.936

Genome annotation databases

EnsembliENSGALT00000003946; ENSGALP00000003937; ENSGALG00000002503
GeneIDi395308
KEGGigga:395308

Similar proteinsi

Entry informationi

Entry nameiQ90XB2_CHICK
AccessioniPrimary (citable) accession number: Q90XB2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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