BRCA1-associated RING domain protein - Xenopus laevis (African clawed frog)

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Unreviewed, UniProtKB/TrEMBL Q90X95 (Q90X95_XENLA)

Last modified November 3, 2009. Version 44. History...

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Names and origin · Protein attributes · Ontologies · Binary interactions · Sequences · References · Cross-references · Entry information

Names and origin

Protein names

Submitted name:
BRCA1-associated RING domain protein EMBL AAL13038.1

Gene names

Name:	bard1 Xenbase XB-FEAT-492034
Synonyms:	BARD1 EMBL AAL13038.1

Organism

Xenopus laevis (African clawed frog) EMBL AAL13038.1

Taxonomic identifier

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Mesobatrachia › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus

Protein attributes

Sequence length	772 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

Ontologies

Keywords
Domain	ANK repeat RuleBase RU003321V2 Repeat RuleBase RU003536V1 Zinc-finger RuleBase RU000353V2
Ligand	Metal-binding Zinc
Gene Ontology (GO)
Cellular component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	protein binding Inferred from physical interaction. Source: IntAct zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
BRCA1	Q90X96	1	EBI-1165318,EBI-1165296

Sequences

Sequence

Length

Mass (Da)

Tools

Q90X95-1 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 2BA4E6DDD56117B3
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772

86,915

        10         20         30         40         50         60 
MLLRVRSGNR PSETAVREEL PMMDEPGWER TRDALREMER KLCCSKCMFI LKDPVCLGGC 

        70         80         90        100        110        120 
EHVFCWTCVN ENLGNECPLC NTPAWVRDVQ VNRQLDNMIQ LCAKLRNLLS MGKTDENKMD 

       130        140        150        160        170        180 
LCQDTLLRLN PAQEKQKKKQ IKMWFSPRSR KVRCVVEKKE KSQQISSKTL PQMASYEFVS 

       190        200        210        220        230        240 
DSPDGEPAQK KPDPKPRKRM KKKLKDINAE WGVDTENEID EVSNPRKEHK SGKSVSFCSS 

       250        260        270        280        290        300 
AVIQHSPEVL VVESSLKNDT PEEISPNWNK CGLDEPMEMQ STSMKEVNCP SPSEQSTTLK 

       310        320        330        340        350        360 
TQDKEKKITT VKRKKHSSPI ASSKRPRRRS SDTSKPLNDS DIKANSPEKA CKTVSPHKPS 

       370        380        390        400        410        420 
ENSAKDVRIE STQAAKRDTK MCSTPLPCAK QNNSAKLGQK STAMPISPNN LTNVKRNYKG 

       430        440        450        460        470        480 
ETMLHLASIK GDIQGVEDLL NSGANPNVKD NAGWTPLHEA CNLGHTMVVQ LLLQHHALMN 

       490        500        510        520        530        540 
TTGYQNDTPL HDAVKNGHIA IVKLLLSHGA SRDAVNIFGL QPVDYAETEE MKSVLLETQT 

       550        560        570        580        590        600 
ERDRLLLHPC LAAPQLSSHQ RKEEAVVLIA SGLLATQRAD LTKLAKMLKA SICAEYDSTV 

       610        620        630        640        650        660 
THVIVSDEPV LRTMKCMMGI LAGCWTLQFS WVKACLQSCN REPEESYEIP HGPHRARLNG 

       670        680        690        700        710        720 
QQMLPQLLDG CHFYFLGCFT EHRKEDLIEL VKAAGGQILI RQPKPDSDVT QTINTVAYHA 

       730        740        750        760        770 
EADSDQRFCT QYIVFDRASK YRPERVRQGK VWFAPSSWII ECITSFQLLP VH

References

[1]	"Functional communication between endogenous BRCA1 and its partner, BARD1, during Xenopus laevis development." Joukov V., Chen J., Fox E.A., Green J.B., Livingston D.M. Proc. Natl. Acad. Sci. U.S.A. 98:12078-12083(2001) [PubMed: 11593018] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
	AF416869 mRNA. Translation: AAL13038.1.
RefSeq	NP_001082131.1.
UniGene	Xl.12056
3D structure databases
HSSP	HSSP built from PDB template 1JM7 based on UniProtKB Q99728.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q90X95. 2 interactions.
Genome annotation databases
GeneID	398242.
KEGG	xla:398242.
Organism-specific databases
CTD	398242.
Xenbase	XB-FEAT-492034. bard1.
Phylogenomic databases
HOVERGEN	Q90X95.
Family and domain databases
InterPro	IPR002110. Ankyrin_rpt. IPR020683. Ankyrin_rpt-contain_dom. IPR001357. BRCT. IPR001841. Znf_RING. IPR017907. Znf_RING_CS. [Graphical view]
Gene3D	G3DSA:1.25.40.20. ANK. 1 hit.
Pfam	PF00023. Ank. 3 hits. PF00533. BRCT. 2 hits. [Graphical view]
SMART	SM00248. ANK. 3 hits. SM00292. BRCT. 2 hits. SM00184. RING. 1 hit. [Graphical view]
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 3 hits. PS50172. BRCT. 2 hits. PS00518. ZF_RING_1. 1 hit. PS50089. ZF_RING_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q90X95_XENLA

Accession

Primary (citable) accession number: Q90X95

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	November 3, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Names and origin · Protein attributes · Ontologies · Binary interactions · Sequences · References · Cross-references · Entry information