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Q90VZ9 (HXA7_CHICK) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Homeobox protein Hox-A7
Gene names
Name:HOXA7
Synonyms:HOXA-7
OrganismGallus gallus (Chicken)
Taxonomic identifier9031 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length219 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the Antp homeobox family.

Contains 1 homeobox DNA-binding domain.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   DomainHomeobox
   LigandDNA-binding
   Molecular functionDevelopmental protein
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processtranscription, DNA-dependent

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 219219Homeobox protein Hox-A7
PRO_0000200075

Regions

DNA binding129 – 18860Homeobox
Motif118 – 1236Antp-type hexapeptide
Compositional bias212 – 2198Asp/Glu-rich (highly acidic)

Sequences

Sequence LengthMass (Da)Tools
Q90VZ9 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 4BAE9046D52C0705

FASTA21924,953
        10         20         30         40         50         60 
MSSSYYVNAL FSKYTAGASL FQNAEPTSCS FASNSQRSGY GPGAGAFASS MPGLYNVNST 

        70         80         90        100        110        120 
IYQSPFSSGY SLGSDAYNLH CSSFDQNIPV LCNDLTKPSC EKAEESNLHN QAEANFRIYP 

       130        140        150        160        170        180 
WMRSSGPDRK RGRQTYTRYQ TLELEKEFHF NRYLTRRRRI EIAHALCLTE RQIKIWFQNR 

       190        200        210 
RMKWKKEHKE ESSSTPAPNE PTSAAASVEK VEEDEEEED

« Hide

References

[1]"Gradients and forward spreading of vertebrate Hox gene expression detected using a Hox/lacZ transgene."
Gaunt S.J.
Dev. Dyn. 221:26-36(2001) [PubMed: 11357191] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Expression and regulation of HOXA5, HOXA6 and HOXA7 during chick wing development."
Oberg K.C., Pira C.U., Creamer D.H., Revelli J.-P., Eichele G.
Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AJ291729 Genomic DNA. Translation: CAC37629.1.
AF408695 mRNA. Translation: AAL01899.1.
IPIIPI00573429.
RefSeqNP_989926.1. NM_204595.1.
UniGeneGga.5122.

3D structure databases

ProteinModelPortalQ90VZ9.
SMRQ90VZ9. Positions 129-189.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID395290.
KEGGgga:395290.

Organism-specific databases

CTD3204.

Phylogenomic databases

eggNOGveNOG13792.
GeneTreeENSGT00600000084133.
HOGENOMHBG715745.
HOVERGENHBG016849.
InParanoidQ90VZ9.
OrthoDBEOG4W9J4Z.

Family and domain databases

InterProIPR001356. Homeobox.
IPR017995. Homeobox_antennapedia.
IPR001827. Homeobox_Antennapedia_CS.
IPR017970. Homeobox_CS.
IPR020479. Homeobox_eu.
IPR009057. Homeodomain-like.
IPR012287. Homeodomain-rel.
[Graphical view]
Gene3DG3DSA:1.10.10.60. Homeodomain-rel. 1 hit.
KOK09307.
PfamPF00046. Homeobox. 1 hit.
[Graphical view]
PRINTSPR00025. ANTENNAPEDIA.
PR00024. HOMEOBOX.
SMARTSM00389. HOX. 1 hit.
[Graphical view]
SUPFAMSSF46689. Homeodomain_like. 1 hit.
PROSITEPS00032. ANTENNAPEDIA. 1 hit.
PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameHXA7_CHICK
AccessionPrimary (citable) accession number: Q90VZ9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: December 1, 2001
Last modified: December 14, 2011
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

Vertebrate homeotic Hox proteins

Nomenclature of vertebrate homeotic Hox proteins and list of entries

SIMILARITY comments

Index of protein domains and families

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