Reviewed,
UniProtKB/Swiss-Prot Q90VZ3 (LYG_PAROL)
Last modified
June 16, 2009.
Version 32.
History...
Clusters with 100%,
90%,
50% identity |
Documents (2) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Lysozyme g EC=3.2.1.17 Alternative name(s): 1,4-beta-N-acetylmuramidase |
| Organism | Paralichthys olivaceus (Japanese flounder) |
| Taxonomic identifier | 8255 [NCBI] |
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Euteleostei › Neoteleostei › Acanthomorpha › Acanthopterygii › Percomorpha › Pleuronectiformes › Pleuronectoidei › Paralichthyidae › Paralichthys |
Protein attributes
| Sequence length | 195 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Possesses lytic activity against M.lysodeikticus and several fish pathogenic bacteria. |
| Catalytic activity | Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins. |
| Tissue specificity | Ubiquitous. Ref.1 |
| Sequence similarities | Belongs to the glycosyl hydrolase 23 family. |
| Biophysicochemical properties | pH dependence: Optimum pH is 6.0. Temperature dependence: Optimum temperature is 25 degrees Celsius. |
Ontologies
| Keywords | |
|---|---|
| Molecular function | Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase |
| Gene Ontology (GO) | |
| Biological process | cell wall macromolecule catabolic process Inferred from electronic annotation. Source: InterPro cytolysisInferred from electronic annotation. Source: UniProtKB-KW defense response to bacteriumInferred from electronic annotation. Source: UniProtKB-KW peptidoglycan catabolic processInferred from electronic annotation. Source: InterPro |
| Molecular function | lysozyme activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
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References
| [1] | "Molecular cloning, expression and evolution of the Japanese flounder goose-type lysozyme gene, and the lytic activity of its recombinant protein." Hikima J., Minagawa S., Hirono I., Aoki T. Biochim. Biophys. Acta 1520:35-44(2001) [PubMed: 11470157] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], CHARACTERIZATION, TISSUE SPECIFICITY. |
Cross-references
Sequence databases | |
|---|---|
| AB050591 Genomic DNA. Translation: BAB62407.1. AB050590 mRNA. Translation: BAB62406.1. | |
3D structure databases | |
| HSSP | HSSP built from PDB template 153L based on UniProtKB P00718. |
| ModBase | Search... |
Protein family/group databases | |
| CAZy | GH23. Glycoside Hydrolase Family 23. |
Phylogenomic databases | |
| HOVERGEN | Q90VZ3. |
Enzyme and pathway databases | |
| BRENDA | 3.2.1.17. 74107. |
Family and domain databases | |
| InterPro | IPR002152. Glyco_hydro_23. IPR008258. Lytic_TGlycosylase-like_cat. [Graphical view] |
| Pfam | PF01464. SLT. 1 hit. [Graphical view] |
| PIRSF | PIRSF001065. Lysozyme_g. 1 hit. |
| PRINTS | PR00749. LYSOZYMEG. |
| ProtoNet | Search... |
Entry information
| Entry name | LYG_PAROL | ||||||||
| Accession | Primary (citable) accession number: Q90VZ3 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
Relevant documents
| Glycosyl hydrolases Classification of glycosyl hydrolase families and list of entries |
| SIMILARITY comments Index of protein domains and families |

Clusters with


