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Protein
Submitted name:

Transforming growth factor beta receptor 3

Gene

TGFBR3

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • animal organ regeneration Source: AgBase
  • cardiac epithelial to mesenchymal transition Source: BHF-UCL
  • cell growth Source: AgBase
  • cell migration Source: BHF-UCL
  • embryonic digestive tract development Source: AgBase
  • embryonic organ development Source: AgBase
  • endothelial cell activation Source: AgBase
  • epithelial to mesenchymal transition Source: BHF-UCL
  • eye development Source: AgBase
  • heart development Source: AgBase
  • heart morphogenesis Source: BHF-UCL
  • immune response Source: Ensembl
  • intracellular signal transduction Source: Ensembl
  • kidney development Source: AgBase
  • liver development Source: AgBase
  • lung development Source: AgBase
  • mesenchymal cell differentiation Source: AgBase
  • negative regulation of cell adhesion Source: AgBase
  • negative regulation of cell-cell adhesion Source: AgBase
  • negative regulation of cellular component movement Source: Ensembl
  • negative regulation of transforming growth factor beta receptor signaling pathway Source: AgBase
  • nervous system development Source: AgBase
  • pathway-restricted SMAD protein phosphorylation Source: Ensembl
  • positive regulation of cell migration Source: AgBase
  • positive regulation of gene expression Source: AgBase
  • positive regulation of transforming growth factor beta receptor signaling pathway Source: AgBase
  • protein-containing complex assembly Source: AgBase
  • regulation of protein binding Source: AgBase
  • response to follicle-stimulating hormone Source: Ensembl
  • response to hypoxia Source: AgBase
  • response to luteinizing hormone Source: Ensembl
  • response to prostaglandin E Source: Ensembl
  • transforming growth factor beta receptor complex assembly Source: AgBase

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
Transforming growth factor beta receptor 3Imported
Submitted name:
Transforming growth factor-beta type III receptorImported
Gene namesi
Name:TGFBR3Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei775 – 799HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane, SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501431241921 – 841Sequence analysisAdd BLAST821

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSGALG00000006038

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ90998, 1 interactor
STRINGi9031.ENSGALP00000032713

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini446 – 723ZPInterPro annotationAdd BLAST278

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IK7K Eukaryota
ENOG410XSMK LUCA
GeneTreeiENSGT00530000063861
HOGENOMiHOG000090193
HOVERGENiHBG057515
KOiK05843
OMAiIIENICP
OrthoDBiEOG091G030O
TreeFamiTF337375

Family and domain databases

InterProiView protein in InterPro
IPR001507 ZP_dom
IPR017977 ZP_dom_CS
PfamiView protein in Pfam
PF00100 Zona_pellucida, 1 hit
PRINTSiPR00023 ZPELLUCIDA
SMARTiView protein in SMART
SM00241 ZP, 1 hit
PROSITEiView protein in PROSITE
PS00682 ZP_1, 1 hit
PS51034 ZP_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q90998-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSSCVTPVF ALMILCFADA GPVPRSECVL SPVNSSHPVH ALLESFTVLS
60 70 80 90 100
GCASRGTTGL PQEVHVLNLR NPDEGLDHHE REVTLHLTPI SSVHIHQKPL
110 120 130 140 150
VFLLNSPLPL VWKLKTERLA PGIRRVFFVS SGSIVWFEKG NFSLSAETEE
160 170 180 190 200
KNFPERNEHL LQWAQKEYGA VTSFTELKIS RNIYIKVGED QVFPPTCNIE
210 220 230 240 250
KNFLSLNYLA GYLQPKRAEG CLMSNLVQER EVHIIELITP NSNPYSAFQV
260 270 280 290 300
DIIVDIKPSQ PGAKLERNVV LILKCKKSVN WVIKSHDVQG KLEVITSNSI
310 320 330 340 350
GFGKETERSM TMSKSVIPDI PSSHESLIKW AYEHKYSPVT SYTKAPVANR
360 370 380 390 400
FHLQLEHTEE MNDEEDHSLP PELTELLHGA KNPALSDGLT FPFHINRGGH
410 420 430 440 450
ETGGEGIFPS RDSVDTLINH DFEHSLSKHK EPEEVQGSAD VALSIKCDDK
460 470 480 490 500
VMTVAVEKDS LQASGYTRTE LSLLDHSCKA RMNGTHFILE SLPNKCGTRT
510 520 530 540 550
SYILDKIVYF NSIVIQLSSP AEGSSFDDDD MESGDNGFPG DADEGDVTFS
560 570 580 590 600
NWPEIAFNCT LHQPEKDFFN PAMFWPPEPH ITNVTFNMEL YKTDLFLAPS
610 620 630 640 650
QGLFSVAENG PIYVEVSVTK ADISLGFAIQ TCFVSPFSNP DRMSDYTIIE
660 670 680 690 700
NICPKDESVK FYSTEKLNFP IAHAQKDKKR FSFVFKPIFN ISLLFLHCEL
710 720 730 740 750
TLCTNIDKDT QRLPKCVPPD EACTSLNVDM ILAMMHNKKT FTKPLVITHE
760 770 780 790 800
GKPEDSSLPK SNVRQPSVFY GLDTLTVVGI AFAAFVIGAL LTGALWFIYS
810 820 830 840
HTGEAAGRRQ VPTSPPASEN SSAAHSIGST QSTPCSSSSA T
Length:841
Mass (Da):93,313
Last modified:November 1, 1996 - v1
Checksum:iBFDEA3FCCBFFFB72
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN04000343 Genomic DNA No translation available.
L01121 mRNA Translation: AAA49090.1
PIRiI50428
RefSeqiNP_989670.1, NM_204339.1
UniGeneiGga.804

Genome annotation databases

EnsembliENSGALT00000033354; ENSGALP00000032713; ENSGALG00000006038
GeneIDi374251
KEGGigga:374251

Similar proteinsi

Entry informationi

Entry nameiQ90998_CHICK
AccessioniPrimary (citable) accession number: Q90998
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 20, 2018
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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