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Protein

Transcriptional regulator Erg

Gene

ERG

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Acts as a transcriptional activator.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi310 – 390ETSPROSITE-ProRule annotationAdd BLAST81

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulator Erg
Gene namesi
Name:ERG
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002041051 – 478Transcriptional regulator ErgAdd BLAST478

Proteomic databases

PaxDbiQ90837

Expressioni

Tissue specificityi

Expressed in mesoderm- and, to a lesser extent, in ectoderm-derived tissues.

Gene expression databases

BgeeiENSGALG00000016058
ExpressionAtlasiQ90837 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000029713

Structurei

3D structure databases

ProteinModelPortaliQ90837
SMRiQ90837
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini113 – 199PNTPROSITE-ProRule annotationAdd BLAST87

Sequence similaritiesi

Belongs to the ETS family.Curated

Phylogenomic databases

eggNOGiKOG3806 Eukaryota
ENOG410Z0ZF LUCA
GeneTreeiENSGT00760000118907
HOGENOMiHOG000290658
HOVERGENiHBG001553
InParanoidiQ90837
KOiK09435
OMAiLPASHMP
OrthoDBiEOG091G0EWP
PhylomeDBiQ90837
TreeFamiTF350537

Family and domain databases

Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR000418 Ets_dom
IPR003118 Pointed_dom
IPR001660 SAM
IPR013761 SAM/pointed_sf
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF00178 Ets, 1 hit
PF02198 SAM_PNT, 1 hit
PRINTSiPR00454 ETSDOMAIN
SMARTiView protein in SMART
SM00413 ETS, 1 hit
SM00251 SAM_PNT, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
SSF47769 SSF47769, 1 hit
PROSITEiView protein in PROSITE
PS00345 ETS_DOMAIN_1, 1 hit
PS00346 ETS_DOMAIN_2, 1 hit
PS50061 ETS_DOMAIN_3, 1 hit
PS51433 PNT, 1 hit

Sequencei

Sequence statusi: Complete.

Q90837-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASTIKEALS VVSEDQSLFE CAYGSPHLAK TEMTASSSSE YGQTSKMSPR
60 70 80 90 100
VPQQDWLSQP PARVTIKMEC NPNQVNGSRN SPDDCSVAKG GKMVSSSDNV
110 120 130 140 150
GMNYGSYMEE KHIPPPNMTT NERRVIVPAD PTLWSTDHVR QWLEWAVKEY
160 170 180 190 200
GLPDVDILLF QNIDGKELCK MTKDDFQRLT PSYNADILLS HLHYLRETPL
210 220 230 240 250
PHLTSDDVDK ALQNSPRLMH ARNTGGATFI FPNTSVYPEA TQRITTRPDL
260 270 280 290 300
PYEQARRSAW TSHSHPTQSK ATQPSSSTVP KTEDQRPQLD PYQILGPTSS
310 320 330 340 350
RLANPGSGQI QLWQFLLELL SDSSNSNCIT WEGTNGEFKM TDPDEVARRW
360 370 380 390 400
GERKSKPNMN YDKLSRALRY YYDKNIMTKV HGKRYAYKFD FHGIAQALQP
410 420 430 440 450
HPPESSMYKY PSDLPYMSSY HAHPQKMNFV APHPPALPVT SSSFFAAPNP
460 470
YWNSPTGGIY PNTRLPAAHM PSHLGTYY
Length:478
Mass (Da):53,913
Last modified:November 1, 1996 - v1
Checksum:i8DFDB243ED8623A7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X77159 mRNA Translation: CAA54404.1
PIRiS60754
RefSeqiNP_989611.1, NM_204280.1
UniGeneiGga.2064

Genome annotation databases

EnsembliENSGALT00000030350; ENSGALP00000029713; ENSGALG00000016058
GeneIDi374146
KEGGigga:374146

Similar proteinsi

Entry informationi

Entry nameiERG_CHICK
AccessioniPrimary (citable) accession number: Q90837
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health