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Protein
Submitted name:

Amyloid protein

Gene

IAPP

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Amyloid proteinImported
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:IAPPImported
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 1

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2222Sequence analysisAdd
BLAST
Chaini23 – 135113Sequence analysisPRO_5007715490Add
BLAST

Expressioni

Gene expression databases

BgeeiENSGALG00000013168.

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000021476.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini78 – 12043CALCITONINInterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J0NB. Eukaryota.
ENOG410Z7V7. LUCA.
GeneTreeiENSGT00510000048671.
HOGENOMiHOG000038203.
HOVERGENiHBG096065.
KOiK08039.
OMAiQEWILPI.
OrthoDBiEOG091G15QG.
PhylomeDBiQ90743.
TreeFamiTF330783.

Family and domain databases

InterProiIPR021117. Calcitonin-like.
IPR021116. Calcitonin/adrenomedullin.
IPR018360. Calcitonin_CS.
IPR001693. Calcitonin_peptide-like.
IPR000443. Pro-islet_amyloid_polypep.
[Graphical view]
PANTHERiPTHR10505. PTHR10505. 1 hit.
PfamiPF00214. Calc_CGRP_IAPP. 1 hit.
[Graphical view]
PRINTSiPR00818. ISLETAMYLOID.
SMARTiSM00113. CALCITONIN. 1 hit.
[Graphical view]
PROSITEiPS00258. CALCITONIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q90743-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCNLKLSAFF IVLSVTLNCL EATSIEKLLS VTDDLSDGTS KRQEWILPIM
60 70 80 90 100
SQNTLSGLSE EMPEQPAAKT KSSHQLEKRK CNTATCVTQR LADFLVRSSS
110 120 130
NIGAIYSPTN VGSNTYGKRD TAGLSSRKSQ NNTKL
Length:135
Mass (Da):14,762
Last modified:November 1, 1996 - v1
Checksum:i83DE3223AC735159
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN03001495 Genomic DNA. No translation available.
L16955 mRNA. Translation: AAA67704.1.
PIRiA56855.
RefSeqiNP_990728.1. NM_205397.1.
UniGeneiGga.780.

Genome annotation databases

EnsembliENSGALT00000021509; ENSGALP00000021476; ENSGALG00000013168.
GeneIDi396362.
KEGGigga:396362.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AADN03001495 Genomic DNA. No translation available.
L16955 mRNA. Translation: AAA67704.1.
PIRiA56855.
RefSeqiNP_990728.1. NM_205397.1.
UniGeneiGga.780.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000021476.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGALT00000021509; ENSGALP00000021476; ENSGALG00000013168.
GeneIDi396362.
KEGGigga:396362.

Organism-specific databases

CTDi3375.

Phylogenomic databases

eggNOGiENOG410J0NB. Eukaryota.
ENOG410Z7V7. LUCA.
GeneTreeiENSGT00510000048671.
HOGENOMiHOG000038203.
HOVERGENiHBG096065.
KOiK08039.
OMAiQEWILPI.
OrthoDBiEOG091G15QG.
PhylomeDBiQ90743.
TreeFamiTF330783.

Gene expression databases

BgeeiENSGALG00000013168.

Family and domain databases

InterProiIPR021117. Calcitonin-like.
IPR021116. Calcitonin/adrenomedullin.
IPR018360. Calcitonin_CS.
IPR001693. Calcitonin_peptide-like.
IPR000443. Pro-islet_amyloid_polypep.
[Graphical view]
PANTHERiPTHR10505. PTHR10505. 1 hit.
PfamiPF00214. Calc_CGRP_IAPP. 1 hit.
[Graphical view]
PRINTSiPR00818. ISLETAMYLOID.
SMARTiSM00113. CALCITONIN. 1 hit.
[Graphical view]
PROSITEiPS00258. CALCITONIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ90743_CHICK
AccessioniPrimary (citable) accession number: Q90743
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.