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Protein
Submitted name:

AE2-1 anion exchanger

Gene

AE2

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. inorganic anion exchanger activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
AE2-1 anion exchangerImported
Gene namesi
Name:AE2Imported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ90710.

Structurei

3D structure databases

ProteinModelPortaliQ90710.
SMRiQ90710. Positions 684-725, 1112-1143.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG004326.
KOiK13855.
PhylomeDBiQ90710.

Family and domain databases

Gene3Di3.40.1100.10. 2 hits.
InterProiIPR001717. Anion_exchange.
IPR002978. Anion_exchange_2.
IPR018241. Anion_exchange_CS.
IPR013769. Band3_cytoplasmic_dom.
IPR011531. HCO3_transpt_C.
IPR003020. HCO3_transpt_euk.
IPR016152. PTrfase/Anion_transptr.
[Graphical view]
PANTHERiPTHR11453. PTHR11453. 1 hit.
PTHR11453:SF14. PTHR11453:SF14. 1 hit.
PfamiPF07565. Band_3_cyto. 1 hit.
PF00955. HCO3_cotransp. 1 hit.
[Graphical view]
PRINTSiPR00165. ANIONEXCHNGR.
PR01188. ANIONEXHNGR2.
PR01231. HCO3TRNSPORT.
SUPFAMiSSF55804. SSF55804. 2 hits.
TIGRFAMsiTIGR00834. ae. 1 hit.
PROSITEiPS00219. ANION_EXCHANGER_1. 1 hit.
PS00220. ANION_EXCHANGER_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q90710-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSRSPVSSEL HHIVSSAIES PEPPAPGPAS PPLAEEEEKD LNKALGVERF
60 70 80 90 100
EEILSDAHPR SVEEPGRIYG EEDFEYHRQS SLHIHHPLSA HLPPDARRKK
110 120 130 140 150
GVPKKGRKKR GRAAAPGENP PIEEGEEDEE EACDTETERS AEELRGGPAE
160 170 180 190 200
GVQFFLQEDE VTERRAEEPP APPAPPGPTA EPHGATAPAA ASPGAEEGRA
210 220 230 240 250
ADGGAVPEDG GSPGRPAARA TEHRSYNLHE RRRIGSMTGA DEAQYQKVPT
260 270 280 290 300
DESEAQTLAS ADLDYMKSHR FEDVPGVRRH LVRKSAKAQV VHVGKEHREQ
310 320 330 340 350
SARPRRSDRQ PHEVFVELNE LVLDKNQELQ WKETARWIKF EEDVEEETDR
360 370 380 390 400
WGKPHVASLS FRSLLELRKT LSHGAVLLDL DQKTLPGVAH QVVEQMVITD
410 420 430 440 450
QIRAEDRANV LRALLLKHSH PSDEKEFSFP RNISAGSLGS LLVHHHSTNH
460 470 480 490 500
VGEGGEPAVT EPLIAGHGAE HDARVDVERE REVPTPAPPA GITRSKSKHE
510 520 530 540 550
LKLLEKIPDN AEATVVLVGC VEFLDQPTMA FVRLQEAVEL DSVLEVPVPV
560 570 580 590 600
RFLFLLLGPS STHMDYHEIG RSISTLMSDK QFHEAAYLAD DRHDLLTAIN
610 620 630 640 650
EFLDCSVVVP PSEVQGEELR SVAHFQREML KKREEQEKRM LLEPKSPEEK
660 670 680 690 700
ALLKLKVAED EDEDDPLRRT GRPFGGLIRD VRRRYPHYLS DFRDALNPQC
710 720 730 740 750
IAAVIFIYFA ALSPAITFGG LLGEKTQDLI GVSELIISTS LQGVLFCLLG
760 770 780 790 800
AQPLLVIGFS GPLLVFEEAF FTFCTSNGLE YLVGRVWIGF WLILIVLLMV
810 820 830 840 850
ACEGSFLVRF VSRFTQEIFA FLISLIFIYE TFSKLGKIFQ EHPLHGCAQP
860 870 880 890 900
NGTAWSNGTA APNGTAQRGA AKVTGQPNTA LLSLVLMAGT FFIAFFLRKF
910 920 930 940 950
KNSRFFPGRI RRLIGDFGVP IAILVMVLVD YSIRDTYTQK LSVPSGFSVT
960 970 980 990 1000
APDKRGWVIN PLGERSDFPV WMMVASGLPA VLVFILIFME TQITTLIISK
1010 1020 1030 1040 1050
KERMLQKGSG FHLDLLLIVA MGGFFALFGL PWLAAATVRS VTHANALTVM
1060 1070 1080 1090 1100
SKAVAPGDKP KIQEVKEQRV TGLLVAVLVG LSIVIGELLR QIPLAVLFGI
1110 1120 1130 1140 1150
FLYMGVTSLN GIQFYERLQL LLMPPKHHPD VPYVKKVRTR MHLFTGLQLA
1160 1170 1180 1190 1200
CLAVLWAVMS TVASLAFPFI LILTVPVRMC LLSRIFTDRE MKCLDADEAE
1210
PILDEREGVD EYNEMPMPV
Length:1,219
Mass (Da):135,289
Last modified:November 1, 1996 - v1
Checksum:i25F42A73C3483B21
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U48889 mRNA. Translation: AAC59881.1.
RefSeqiNP_990294.1. NM_204963.1.
UniGeneiGga.1335.

Genome annotation databases

GeneIDi395809.
KEGGigga:395809.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U48889 mRNA. Translation: AAC59881.1.
RefSeqiNP_990294.1. NM_204963.1.
UniGeneiGga.1335.

3D structure databases

ProteinModelPortaliQ90710.
SMRiQ90710. Positions 684-725, 1112-1143.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ90710.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi395809.
KEGGigga:395809.

Organism-specific databases

CTDi6522.

Phylogenomic databases

HOVERGENiHBG004326.
KOiK13855.
PhylomeDBiQ90710.

Miscellaneous databases

NextBioi20815877.
PROiQ90710.

Family and domain databases

Gene3Di3.40.1100.10. 2 hits.
InterProiIPR001717. Anion_exchange.
IPR002978. Anion_exchange_2.
IPR018241. Anion_exchange_CS.
IPR013769. Band3_cytoplasmic_dom.
IPR011531. HCO3_transpt_C.
IPR003020. HCO3_transpt_euk.
IPR016152. PTrfase/Anion_transptr.
[Graphical view]
PANTHERiPTHR11453. PTHR11453. 1 hit.
PTHR11453:SF14. PTHR11453:SF14. 1 hit.
PfamiPF07565. Band_3_cyto. 1 hit.
PF00955. HCO3_cotransp. 1 hit.
[Graphical view]
PRINTSiPR00165. ANIONEXCHNGR.
PR01188. ANIONEXHNGR2.
PR01231. HCO3TRNSPORT.
SUPFAMiSSF55804. SSF55804. 2 hits.
TIGRFAMsiTIGR00834. ae. 1 hit.
PROSITEiPS00219. ANION_EXCHANGER_1. 1 hit.
PS00220. ANION_EXCHANGER_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Variant AE2 anion exchanger transcripts accumulate in multiple cell types in the chicken gastric epithelium."
    Cox K.H., Adair-Kirk T.L., Cox J.V.
    J. Biol. Chem. 271:8895-8902(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: ProventriculusImported.

Entry informationi

Entry nameiQ90710_CHICK
AccessioniPrimary (citable) accession number: Q90710
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: February 4, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.