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Q90699 (Q90699_CHICK) Unreviewed, UniProtKB/TrEMBL

Last modified April 3, 2013. Version 95. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Tyrosine-protein kinase receptor RuleBase RU000312
EC=2.7.10.1 RuleBase RU000312
Gene names
Name:ctrkA EMBL AAA85289.1
OrganismGallus gallus (Chicken) EMBL AAA85289.1
Taxonomic identifier9031 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length790 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. RuleBase RU000312 SAAS SAAS008266

Sequence similarities

Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. RuleBase RU000312

Contains 1 LRRCT domain. SAAS SAAS013098

Contains 1 protein kinase domain. SAAS SAAS008266

Sequences

Sequence LengthMass (Da)Tools
Q90699 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: AD2314608F30AD71

FASTA79088,670
        10         20         30         40         50         60 
MLPAWLRLCL AALLLPPGAA VPPACPAHCR CPASHTLRCR EPLTVSSLSA LLLGAHRPTD 

        70         80         90        100        110        120 
VIIENQALLT SLTRDDTRML WDLRHLTISN SGLQYISDDA FQDNHRLSHV NLSFNALTSL 

       130        140        150        160        170        180 
SWKTFQYLPL QELILEGNPF NCSCGIRWLQ LWQNGSRAEL GNQSLLCWEG SMLVALDSHP 

       190        200        210        220        230        240 
LHDCEPPTAR IEHPDVVLRQ GDSVNLTCHI WGEPSATGEW VLPHVGSEPS VTKLSEWELV 

       250        260        270        280        290        300 
LEINNISSSL NHKDLTCRAE NAVGLAEDSV MLNVTFPPVI LLLSEAIPQH FWCIPFSVDS 

       310        320        330        340        350        360 
NPTPRILWLF NGSMLPEGPY IHTRIVEYEP NSTVLHGCLQ LNRPTHVNNG NYTLVVQNPL 

       370        380        390        400        410        420 
GRATRSIQGR FMDNPFSFSP EEPIPVSISP LGTRNSSLEG PVETADEHTF GVSVAVALAV 

       430        440        450        460        470        480 
FASLFLSVML IALNKCGHRS KFGINRSAVL AQEDDLAMSL HFMNLGSSPV SSTESKLDGL 

       490        500        510        520        530        540 
KSNFIENPQY FCNACVHHVQ RRDIVLKWEL GEGAFGKVFL AECSHLLPEQ EKTLVAVKAL 

       550        560        570        580        590        600 
KEVTESARLD FQREAELLTV LQHEHIVKFY GVCTEGEPLI MVFEYMKHGD LNRFLRSHGP 

       610        620        630        640        650        660 
DAKILDQGQG QPCGQLTLSH MLQIATQIAS GMVYLASLHF VHRDLATRNC LVGHDLVVKI 

       670        680        690        700        710        720 
GDFGMSRDIY STDYYRVGGR TMLPIRWMPP ESILYRKFTT ESDIWSFGVV LWEIFTYGKQ 

       730        740        750        760        770        780 
PWYQLSNTEA IECITQGREL ERPRTCPSEV YDIMQSCWQR EPQQRQRIQD IHSRLQALVK 

       790 
TPPIYLDILG

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References

[1]Schroepel A., Dechant G., Barde Y.A.
Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
[2]"Early expression of the nerve growth factor ctrkA in chicken sympathetic and sensory ganglia."
Schroepel A., v Schack D., Dechant G., Barde Y.A.
Mol. Cell. Neurosci. 6:0-0(0)
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U43396 mRNA. Translation: AAA85289.1.
IPIIPI00579515.
RefSeqNP_990709.1. NM_205378.1.
UniGeneGga.579.

3D structure databases

HSSPHSSP built from PDB template 1LUF based on UniProtKB Q62838.
ProteinModelPortalQ90699.
SMRQ90699. Positions 276-381.
ModBaseSearch...

Protein-protein interaction databases

STRING9031.ENSGALP00000021606.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID396337.
KEGGgga:396337.

Organism-specific databases

CTD4914.

Phylogenomic databases

HOVERGENHBG056735.
KOK03176.

Family and domain databases

Gene3D2.60.40.10. 2 hits.
InterProIPR000483. Cys-rich_flank_reg_C.
IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR013098. Ig_I-set.
IPR003599. Ig_sub.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_cat_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
IPR008266. Tyr_kinase_AS.
IPR020635. Tyr_kinase_cat_dom.
IPR020461. Tyr_kinase_neurotrophic_rcpt_1.
IPR020777. Tyr_kinase_NGF_rcpt.
IPR002011. Tyr_kinase_rcpt_2_CS.
[Graphical view]
PfamPF07679. I-set. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
PRINTSPR01939. NTKRECEPTOR.
PR01940. NTKRECEPTOR1.
PR00109. TYRKINASE.
SMARTSM00409. IG. 1 hit.
SM00082. LRRCT. 1 hit.
SM00219. TyrKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. Kinase_like. 1 hit.
PROSITEPS50835. IG_LIKE. 1 hit.
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00109. PROTEIN_KINASE_TYR. 1 hit.
PS00239. RECEPTOR_TYR_KIN_II. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio20816385.

Entry information

Entry nameQ90699_CHICK
AccessionPrimary (citable) accession number: Q90699
Entry history
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: April 3, 2013
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info