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Protein
Submitted name:

HER-6 protein

Gene

her6

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • anterior/posterior pattern specification Source: ZFIN
  • Notch signaling pathway Source: ZFIN
  • regulation of neurogenesis Source: ZFIN
  • regulation of neuron differentiation Source: ZFIN
  • regulation of transcription, DNA-templated Source: UniProtKB-UniRule
  • somite specification Source: ZFIN
  • thalamus development Source: ZFIN
  • transcription, DNA-templated Source: UniProtKB-UniRule

Keywordsi

Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
HER-6 proteinImported
Gene namesi
Name:her6Imported
Synonyms:HER-6Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-980526-144 her6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

ELMiQ90468

Structurei

3D structure databases

ProteinModelPortaliQ90468
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini98 – 155BHLHInterPro annotationAdd BLAST58
Domaini174 – 207OrangeInterPro annotationAdd BLAST34

Phylogenomic databases

eggNOGiKOG4304 Eukaryota
ENOG4111F0X LUCA
HOGENOMiHOG000236346
HOVERGENiHBG005960
PhylomeDBiQ90468

Family and domain databases

CDDicd00083 HLH, 1 hit
Gene3Di4.10.280.10, 1 hit
InterProiView protein in InterPro
IPR011598 bHLH_dom
IPR036638 HLH_DNA-bd_sf
IPR003650 Orange_dom
PfamiView protein in Pfam
PF07527 Hairy_orange, 1 hit
PF00010 HLH, 1 hit
SMARTiView protein in SMART
SM00353 HLH, 1 hit
SM00511 ORANGE, 1 hit
SUPFAMiSSF47459 SSF47459, 1 hit
PROSITEiView protein in PROSITE
PS50888 BHLH, 1 hit
PS51054 ORANGE, 1 hit

Sequencei

Sequence statusi: Complete.

Q90468-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMKRKIKQTV TSLPHQLNSG HFVRISIHNW NCISVLDSVY STRRSCAGGF
60 70 80 90 100
LFINKITKGY FPEKMPADIM EKNSSSPVAA TPASMNTTPD KPKTASEHRK
110 120 130 140 150
SSKPIMEKRR RARINESLGQ LKTLILDALK KDSSRHSKLE KADILEMTVK
160 170 180 190 200
HLRNMQRAQM TAALNTDPTV LGKYRAGFSE CMNEVTRFLS TCEGVNTEVR
210 220 230 240 250
TRLLGHLASC MTQINAMNYP TQHQILPGLL IHPSVNPWFK IPSATQQANV
260 270 280 290 300
VPLSGVPCKS GSSSNLTSDA TKVYGGFQLV PATDGQFAFL IPNAAFAPNG
310 320 330
PVIPVYANNS NTPVPVAVSP GAPSVTSDSV WRPW
Length:334
Mass (Da):36,632
Last modified:November 1, 1996 - v1
Checksum:iEC043C266E37270C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X97333 mRNA Translation: CAA65998.1
UniGeneiDr.75065

Similar proteinsi

Entry informationi

Entry nameiQ90468_DANRE
AccessioniPrimary (citable) accession number: Q90468
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: January 31, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health