Q90467 (Q90467_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
DNA-binding protein EMBL CAA64616.1

Gene names

Name:	her5 ZFIN ZDB-GENE-990415-90
Synonyms:	her-5 EMBL CAA64616.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL CAA64616.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	205 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 Orange domain. SAAS SAAS003650 Contains 1 basic helix-loop-helix (bHLH) domain. RuleBase RU000367 SAAS SAAS003650

Ontologies

Keywords
Biological process	Transcription Transcription regulation SAAS SAAS003650
Cellular component	Nucleus SAAS SAAS003650
Ligand	DNA-binding EMBL CAA64616.1
Gene Ontology (GO)
Biological process	embryonic organ morphogenesis Inferred from mutant phenotype. Source: ZFIN endoderm development Inferred from mutant phenotype. Source: ZFIN midbrain-hindbrain boundary development Inferred from mutant phenotype. Source: ZFIN negative regulation of neurogenesis Inferred from mutant phenotype. Source: ZFIN positive regulation of cyclin-dependent protein kinase activity Inferred from mutant phenotype. Source: ZFIN transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	nucleus Inferred by curator. Source: ZFIN
Molecular function	DNA binding Inferred from electronic annotation. Source: UniProtKB-KW protein heterodimerization activity Inferred from physical interaction. Source: ZFIN protein homodimerization activity Inferred from physical interaction. Source: ZFIN sequence-specific DNA binding transcription factor activity Non-traceable author statement. Source: ZFIN
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q90467 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 196902284CC7AD16	FASTA	205	23,753
	10 20 30 40 50 60 MEQKDMRRVP KPLMEKRRRD RINQSLETLR MLLLENTNNE KLKNPKVEKA EILESVVHFL 70 80 90 100 110 120 RAEQASETDP FQITRVKRAR TEESDEDVES PCKRQSYHDG MRTCLLRVSN FITGKSHEFG 130 140 150 160 170 180 QELEKACENI HKSHSRQVQL LSTPSLIEPQ VHLYEDPSQQ HLAHVQLSNS CTPSGCSKLA 190 200 QRTVPAMTSS PKQPVMLCDP VWRPW

References

[1]	"Molekulargenetische Untersuchungen an sechs Zebrafisch-Genen mit Homologie zur Enhancer of split Gen-Familie von Drosophila." von Weizsaecker E. Submitted (JAN-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	Von Weizsaecker E.G. Submitted (JAN-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X95301 mRNA. Translation: CAA64616.1.
IPI	IPI00995421.
RefSeq	NP_571152.1. NM_131077.1.
UniGene	Dr.75071.
3D structure databases
ProteinModelPortal	Q90467.
ModBase	Search...
Protein-protein interaction databases
STRING	Q90467.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	30285.
KEGG	dre:30285.
Organism-specific databases
CTD	30285.
ZFIN	ZDB-GENE-990415-90. her5.
Phylogenomic databases
GeneTree	ENSGT00550000074362.
HOVERGEN	HBG098269.
InParanoid	Q90467.
Gene expression databases
ArrayExpress	Q90467.
Bgee	Q90467.
Family and domain databases
InterPro	IPR011598. HLH_DNA-bd. IPR003650. Orange. [Graphical view]
Gene3D	G3DSA:4.10.280.10. HLH_DNA_bd. 1 hit.
Pfam	PF00010. HLH. 1 hit. [Graphical view]
SMART	SM00353. HLH. 1 hit. [Graphical view]
SUPFAM	SSF47459. HLH_basic. 1 hit.
PROSITE	PS50888. HLH. 1 hit. PS51054. ORANGE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q90467_DANRE

Accession

Primary (citable) accession number: Q90467

Entry history

Integrated into UniProtKB/TrEMBL:	November 1, 1996
Last sequence update:	November 1, 1996
Last modified:	December 14, 2011
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)