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Protein
Submitted name:

B-catenin

Gene

ctnnb1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • cadherin binding Source: ZFIN
  • signal transducer activity Source: InterPro

GO - Biological processi

  • adherens junction assembly Source: InterPro
  • cell adhesion Source: ZFIN
  • convergent extension Source: ZFIN
  • determination of dorsal/ventral asymmetry Source: ZFIN
  • dorsal/ventral pattern formation Source: ZFIN
  • ectoderm development Source: ZFIN
  • embryonic axis specification Source: ZFIN
  • liver development Source: ZFIN
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
B-cateninImported
Gene namesi
Name:ctnnb1Imported
Synonyms:ctnnbImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-980526-362. ctnnb1.

Subcellular locationi

GO - Cellular componenti

  • adherens junction Source: ZFIN
  • catenin complex Source: ZFIN
  • cell-cell adherens junction Source: ZFIN
  • cell cortex Source: ZFIN
  • intercalated disc Source: ZFIN
  • membrane Source: ZFIN
  • microvillus Source: ZFIN
  • nucleus Source: ZFIN
  • zonula adherens Source: ZFIN
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ90424.

Interactioni

GO - Molecular functioni

  • cadherin binding Source: ZFIN

Protein-protein interaction databases

STRINGi7955.ENSDARP00000032935.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2Z6GX-ray3.40A1-780[»]
ProteinModelPortaliQ90424.
SMRiQ90424. Positions 19-44, 117-681.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ90424.

Family & Domainsi

Phylogenomic databases

eggNOGiKOG4203. Eukaryota.
COG0035. LUCA.
HOVERGENiHBG000919.
PhylomeDBiQ90424.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
IPR013284. Beta-catenin.
[Graphical view]
PfamiPF00514. Arm. 4 hits.
[Graphical view]
PRINTSiPR01869. BCATNINFAMLY.
SMARTiSM00185. ARM. 12 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50176. ARM_REPEAT. 9 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q90424-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATQSDLMEL EMAMDPDRKA AVSHWQQQSY LDSGIHSGAT TTAPSLSGKG
60 70 80 90 100
NPEDDDVDNQ VLYEWEQGFN QSFNQEQVAD IDGQYAMTRA QRVRAAMFPE
110 120 130 140 150
TLDEGMQIPS TQFDSAHPTN VQRLAEPSQM LKHAVVNLIN YQDDAELATR
160 170 180 190 200
AIPELTKLLN DEDQVVVNKA AVMVHQLSKK EASRHAIMRS PQMVSAIVRT
210 220 230 240 250
MQNTNDVETA RCTSGTLHNL SHHREGLLAI FKSGGIPALV NMLGSPVDSV
260 270 280 290 300
LFHAITTLHN LLLHQEGAKM AVRLAGGLQK MVALLNKTNV KFLAITTDCL
310 320 330 340 350
QILAYGNQES KLIILASGGP QALVNIMRTY TYEKLLWTTS RVLKVLSVCS
360 370 380 390 400
SNKPAIVEAG GMQALGLHLT DPSQRLVQNC LWTLRNLSDA ATKQEGMEGL
410 420 430 440 450
LGTLVQLLGS DDINVVTCAA GILSNLTCNN YKNKMMVCQV GGIEALVRTV
460 470 480 490 500
LRAGDREDIT EPAICALRHL TSRHQDAEMA QNAVRLHYGL PVVVKLLHPP
510 520 530 540 550
SHWPLIKATV GLIRNLALCP ANHAPLREQG AIPRLVQLLV RAHQDTQRRT
560 570 580 590 600
SMGGTQQQFV EGVRMEEIVE ACTGALHILA RDIHNRIVIR GLNTIPLFVQ
610 620 630 640 650
LLYSPIENIQ RVAAGVLCEL AQDKEAAEAI EAEGATAPLT ELLHSRNEGV
660 670 680 690 700
ATYAAAVLFR MSEDKPQDYK KRLSVELTSS LFRTEPMTWN ETGDLGLDIG
710 720 730 740 750
AQGEPLGYRQ DDPSYRSFHS GGYGQDAMGM DPMMEHEMAG HHPGPDYPVD
760 770 780
GLPDLGHTQD LIDGLPPGDS NQLAWFDTDL
Length:780
Mass (Da):85,542
Last modified:November 1, 1996 - v1
Checksum:iD7A1FB80F94066DC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U41081 mRNA. Translation: AAC59732.1.
UniGeneiDr.10259.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U41081 mRNA. Translation: AAC59732.1.
UniGeneiDr.10259.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2Z6GX-ray3.40A1-780[»]
ProteinModelPortaliQ90424.
SMRiQ90424. Positions 19-44, 117-681.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000032935.

Proteomic databases

PaxDbiQ90424.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

ZFINiZDB-GENE-980526-362. ctnnb1.

Phylogenomic databases

eggNOGiKOG4203. Eukaryota.
COG0035. LUCA.
HOVERGENiHBG000919.
PhylomeDBiQ90424.

Miscellaneous databases

EvolutionaryTraceiQ90424.

Family and domain databases

Gene3Di1.25.10.10. 1 hit.
InterProiIPR011989. ARM-like.
IPR016024. ARM-type_fold.
IPR000225. Armadillo.
IPR013284. Beta-catenin.
[Graphical view]
PfamiPF00514. Arm. 4 hits.
[Graphical view]
PRINTSiPR01869. BCATNINFAMLY.
SMARTiSM00185. ARM. 12 hits.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
PROSITEiPS50176. ARM_REPEAT. 9 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ90424_DANRE
AccessioniPrimary (citable) accession number: Q90424
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: May 11, 2016
This is version 105 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.