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Protein
Submitted name:

Zg1

Gene

gata1a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • DNA binding transcription factor activity Source: ZFIN
  • double-stranded DNA binding Source: ZFIN
  • sequence-specific DNA binding Source: ZFIN
  • zinc ion binding Source: InterPro

GO - Biological processi

  • chordate embryonic development Source: ZFIN
  • embryonic hemopoiesis Source: ZFIN
  • erythrocyte development Source: ZFIN
  • erythrocyte differentiation Source: ZFIN
  • macrophage differentiation Source: ZFIN
  • monocyte differentiation Source: ZFIN
  • myeloid cell differentiation Source: ZFIN
  • negative regulation of apoptotic process Source: ZFIN
  • negative regulation of gene expression Source: ZFIN
  • neutrophil differentiation Source: ZFIN
  • positive regulation of transcription by RNA polymerase II Source: ZFIN
  • primitive hemopoiesis Source: ZFIN
  • regulation of myeloid cell differentiation Source: ZFIN

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Zg1Imported
Gene namesi
Name:gata1aImported
Synonyms:gata1Imported, zg1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-980526-268 gata1a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Structurei

3D structure databases

ProteinModelPortaliQ90410
SMRiQ90410
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini232 – 287GATA-typeInterPro annotationAdd BLAST56
Domaini286 – 339GATA-typeInterPro annotationAdd BLAST54

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1601 Eukaryota
COG5641 LUCA
HOVERGENiHBG051705
KOiK09182
PhylomeDBiQ90410

Family and domain databases

Gene3Di3.30.50.10, 2 hits
InterProiView protein in InterPro
IPR016374 TF_GATA-2/3
IPR000679 Znf_GATA
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00320 GATA, 2 hits
PIRSFiPIRSF003027 TF_GATA-1/2/3, 2 hits
PRINTSiPR00619 GATAZNFINGER
SMARTiView protein in SMART
SM00401 ZnF_GATA, 2 hits
PROSITEiView protein in PROSITE
PS00344 GATA_ZN_FINGER_1, 2 hits
PS50114 GATA_ZN_FINGER_2, 2 hits

Sequencei

Sequence statusi: Complete.

Q90410-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENSSEPSRW VSPGLLSPDP LVNYTTDSGL LPPVDVDEPF YSSSETDLLP
60 70 80 90 100
SYYSTSVQSR ASSSYRHSPV RQVYSSQSIL GNIQWLDNSA GHSLNSPYNP
110 120 130 140 150
TSTVWSSSPF PKTPLHSHTS TSIYQNTATP SFTSPKEGFP SPSRDGKDSP
160 170 180 190 200
RLQEVLKAER LSPMSGSGSS FLNLSSATGG VYGPSPHMLS PYGSYMSTSQ
210 220 230 240 250
DYSSAALYST GGPWMSPSSY SPKLRNKMRL SPPEARECVN CGATATPLWR
260 270 280 290 300
QDGTGHYLCN ACGLYHKMNG QNRPLIRPKK RLIVSKRAGT QCANCHTSTT
310 320 330 340 350
TLWRRNASGE PVCNACGLYF KLHNVNRPLT MKKDGIQTRN RKVSNRNKKG
360 370 380 390 400
KKNAASEVYP DMSHMAPPDE HVGAYSLNPG PLLSYSHPAH LLPTSTLHSS
410
TTLPYTHHPN SGMMPTLV
Length:418
Mass (Da):45,663
Last modified:November 1, 1996 - v1
Checksum:iCDB1773A8FD5801B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18311 mRNA Translation: AAA86090.1
RefSeqiNP_571309.1, NM_131234.1
UniGeneiDr.355

Genome annotation databases

GeneIDi30481
KEGGidre:30481

Similar proteinsi

Entry informationi

Entry nameiQ90410_DANRE
AccessioniPrimary (citable) accession number: Q90410
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health