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Protein
Submitted name:

Zg1

Gene

gata1a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • double-stranded DNA binding Source: ZFIN
  • sequence-specific DNA binding Source: ZFIN
  • transcription factor activity, sequence-specific DNA binding Source: ZFIN
  • zinc ion binding Source: InterPro

GO - Biological processi

  • chordate embryonic development Source: ZFIN
  • embryonic hemopoiesis Source: ZFIN
  • erythrocyte development Source: ZFIN
  • erythrocyte differentiation Source: ZFIN
  • macrophage differentiation Source: ZFIN
  • monocyte differentiation Source: ZFIN
  • myeloid cell differentiation Source: ZFIN
  • negative regulation of apoptotic process Source: ZFIN
  • negative regulation of gene expression Source: ZFIN
  • neutrophil differentiation Source: ZFIN
  • positive regulation of transcription from RNA polymerase II promoter Source: ZFIN
  • primitive hemopoiesis Source: ZFIN
  • regulation of myeloid cell differentiation Source: ZFIN
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Zg1Imported
Gene namesi
Name:gata1aImported
Synonyms:gata1Imported, zg1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-980526-268. gata1a.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: ZFIN
Complete GO annotation...

PTM / Processingi

Proteomic databases

PaxDbiQ90410.

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000002330.

Structurei

3D structure databases

ProteinModelPortaliQ90410.
SMRiQ90410. Positions 234-277, 286-349.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini232 – 28756GATA-typeInterPro annotationAdd
BLAST
Domaini286 – 33954GATA-typeInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1601. Eukaryota.
COG5641. LUCA.
HOVERGENiHBG051705.
KOiK09182.
PhylomeDBiQ90410.

Family and domain databases

Gene3Di3.30.50.10. 2 hits.
InterProiIPR000679. Znf_GATA.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00320. GATA. 2 hits.
[Graphical view]
PRINTSiPR00619. GATAZNFINGER.
SMARTiSM00401. ZnF_GATA. 2 hits.
[Graphical view]
PROSITEiPS00344. GATA_ZN_FINGER_1. 2 hits.
PS50114. GATA_ZN_FINGER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q90410-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENSSEPSRW VSPGLLSPDP LVNYTTDSGL LPPVDVDEPF YSSSETDLLP
60 70 80 90 100
SYYSTSVQSR ASSSYRHSPV RQVYSSQSIL GNIQWLDNSA GHSLNSPYNP
110 120 130 140 150
TSTVWSSSPF PKTPLHSHTS TSIYQNTATP SFTSPKEGFP SPSRDGKDSP
160 170 180 190 200
RLQEVLKAER LSPMSGSGSS FLNLSSATGG VYGPSPHMLS PYGSYMSTSQ
210 220 230 240 250
DYSSAALYST GGPWMSPSSY SPKLRNKMRL SPPEARECVN CGATATPLWR
260 270 280 290 300
QDGTGHYLCN ACGLYHKMNG QNRPLIRPKK RLIVSKRAGT QCANCHTSTT
310 320 330 340 350
TLWRRNASGE PVCNACGLYF KLHNVNRPLT MKKDGIQTRN RKVSNRNKKG
360 370 380 390 400
KKNAASEVYP DMSHMAPPDE HVGAYSLNPG PLLSYSHPAH LLPTSTLHSS
410
TTLPYTHHPN SGMMPTLV
Length:418
Mass (Da):45,663
Last modified:November 1, 1996 - v1
Checksum:iCDB1773A8FD5801B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18311 mRNA. Translation: AAA86090.1.
RefSeqiNP_571309.1. NM_131234.1.
UniGeneiDr.355.

Genome annotation databases

GeneIDi30481.
KEGGidre:30481.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U18311 mRNA. Translation: AAA86090.1.
RefSeqiNP_571309.1. NM_131234.1.
UniGeneiDr.355.

3D structure databases

ProteinModelPortaliQ90410.
SMRiQ90410. Positions 234-277, 286-349.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000002330.

Proteomic databases

PaxDbiQ90410.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi30481.
KEGGidre:30481.

Organism-specific databases

CTDi30481.
ZFINiZDB-GENE-980526-268. gata1a.

Phylogenomic databases

eggNOGiKOG1601. Eukaryota.
COG5641. LUCA.
HOVERGENiHBG051705.
KOiK09182.
PhylomeDBiQ90410.

Family and domain databases

Gene3Di3.30.50.10. 2 hits.
InterProiIPR000679. Znf_GATA.
IPR013088. Znf_NHR/GATA.
[Graphical view]
PfamiPF00320. GATA. 2 hits.
[Graphical view]
PRINTSiPR00619. GATAZNFINGER.
SMARTiSM00401. ZnF_GATA. 2 hits.
[Graphical view]
PROSITEiPS00344. GATA_ZN_FINGER_1. 2 hits.
PS50114. GATA_ZN_FINGER_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ90410_DANRE
AccessioniPrimary (citable) accession number: Q90410
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: June 8, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.