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Q903N5 (Q903N5_9HIV1) Unreviewed, UniProtKB/TrEMBL

Last modified March 19, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
OrganismHuman immunodeficiency virus 1 EMBL AAK12468.1
Taxonomic identifier11676 [NCBI]
Taxonomic lineageVirusesRetro-transcribing virusesRetroviridaeOrthoretrovirinaeLentivirusPrimate lentivirus group
Virus hostHomo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length99 AA.
Sequence statusFragment.
Protein existenceEvidence at protein level

General annotation (Comments)

Sequence similarities

Contains peptidase A2 domain. SAAS SAAS018061

Contains peptidase Adomain. SAAS SAAS018061

Ontologies

Keywords
   Molecular functionAspartyl protease RuleBase RU000453
Hydrolase
Protease
   Technical term3D-structure PDB 2AZ8 PDB 2HB4 PDB 2PC0
Gene Ontology (GO)
   Biological_processproteolysis

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionaspartic-type endopeptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL AAK12468.1
Non-terminal residue991 EMBL AAK12468.1

Sequences

Sequence LengthMass (Da)Tools
Q903N5 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 374DA1342EB1500D

FASTA9910,848
        10         20         30         40         50         60 
PQITLWRRPL VTIKIGGQLK EALLDTGADD TVLEEMNLPG RWKPKMIGGI GGFIKVRQYD 

        70         80         90 
QILIEICGHK AIGTVLVGPT PVNIIGRNLL TQIGCTLNF 

« Hide

References

[1]"Analysis of HIV type 1 protease and reverse transcriptase sequences from Venezuela for drug resistance-associated mutations and subtype classification: a UNAIDS study."
Delgado E., Leon-Ponte M., Villahermosa M.L., Cuevas M.T., Deibis L., Echeverria G., Thomson M.M., Perez-Alvarez L., Osmanov S., Najera R.
AIDS Res. Hum. Retroviruses 17:753-758(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
[2]"Conformational flexibility in the flap domains of ligand-free HIV protease."
Heaslet H., Rosenfeld R., Giffin M., Lin Y.C., Tam K., Torbett B.E., Elder J.H., McRee D.E., Stout C.D.
Acta Crystallogr. D 63:866-875(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.40 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY016860 Genomic DNA. Translation: AAK12468.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2HB4X-ray2.15A1-99[»]
2PC0X-ray1.40A1-99[»]
ProteinModelPortalQ903N5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.40.70.10. 1 hit.
InterProIPR001969. Aspartic_peptidase_AS.
IPR018061. Pept_A2A_retrovirus_sg.
IPR001995. Peptidase_A2_cat.
IPR021109. Peptidase_aspartic_dom.
[Graphical view]
PfamPF00077. RVP. 1 hit.
[Graphical view]
SUPFAMSSF50630. SSF50630. 1 hit.
PROSITEPS50175. ASP_PROT_RETROV. 1 hit.
PS00141. ASP_PROTEASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ903N5_9HIV1
AccessionPrimary (citable) accession number: Q903N5
Entry history
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: March 19, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)