ID   Q90320_CYPCA            Unreviewed;       324 AA.
AC   Q90320;
DT   01-NOV-1996, integrated into UniProtKB/TrEMBL.
DT   01-NOV-1996, sequence version 1.
DT   03-MAY-2023, entry version 114.
DE   SubName: Full=Cdx1 protein {ECO:0000313|EMBL:CAA56695.1};
GN   Name=cdx1 {ECO:0000313|EMBL:CAA56695.1};
OS   Cyprinus carpio (Common carp).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Cyprinidae; Cyprininae; Cyprinus.
OX   NCBI_TaxID=7962 {ECO:0000313|EMBL:CAA56695.1};
RN   [1] {ECO:0000313|EMBL:CAA56695.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Whole embryo {ECO:0000313|EMBL:CAA56695.1};
RA   Stroband HWJ.J, Stevens C, te Kronnie G, Samallo J, Schipper H, Kramer B,
RA   Timmermans LPM.M;
RT   "Expression of carp-cdx1, a caudal homolog, in embryos of the carp,
RT   Cyprinus carpio.";
RL   Roux's Arch. Dev. Biol. 204:369-377(1995).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC   -!- SIMILARITY: Belongs to the Caudal homeobox family.
CC       {ECO:0000256|ARBA:ARBA00010341}.
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DR   EMBL; X80668; CAA56695.1; -; mRNA.
DR   PIR; I50125; I50125.
DR   AlphaFoldDB; Q90320; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   CDD; cd00086; homeodomain; 1.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   InterPro; IPR006820; Caudal_activation_dom.
DR   InterPro; IPR047152; Caudal_homeobox.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR017970; Homeobox_CS.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR020479; Homeobox_metazoa.
DR   InterPro; IPR000047; HTH_motif.
DR   PANTHER; PTHR24332; HOMEOBOX PROTEIN CDX; 1.
DR   PANTHER; PTHR24332:SF15; HOMEOBOX PROTEIN CDX-4; 1.
DR   Pfam; PF04731; Caudal_act; 1.
DR   Pfam; PF00046; Homeodomain; 1.
DR   PRINTS; PR00024; HOMEOBOX.
DR   PRINTS; PR00031; HTHREPRESSR.
DR   SMART; SM00389; HOX; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   2: Evidence at transcript level;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW   ProRule:PRU00108};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW   ProRule:PRU00108}.
FT   DOMAIN          149..209
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000259|PROSITE:PS50071"
FT   DNA_BIND        151..210
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT   REGION          128..148
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          215..238
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        128..147
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   324 AA;  36387 MW;  0E092B545E1D9538 CRC64;
     MYVGYLLDKE GSMYHQGSVR RSGISLPPQN FVSTPQYSDF TGYHHVPNMD THAQSAGAWG
     PPYGAPREDW GAYSLGPPNT ISAPMSSSSP GQVSYCSSDY NAMHGPGSAV LPPPPENISV
     GQLSPERERR NSYQWMSKTV QSSSTGKTRT KEKYRVVYTD HQRLELEKEF HFNRYITIRR
     KSELAVNLGL SERQVKIWFQ NRRAKERKLI KKKLGVSDGS GGSVHSDPGS VSPLPVPGVT
     ESVRHTRFSV PTPRNERLTI YEEHTASYCH SVNSNLKDPT LTEHSNTLKG QNRSGPLAWT
     KRITNYYTTG IKARVVDYHR RITS
//