Q90268 (PAX2A_DANRE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Paired box protein Pax-2a

Alternative name(s):
No isthmus protein
Pax[Zf-b]

Gene names

Name:	pax2a
Synonyms:	noi, pax2.1, paxzf-b

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) [Reference proteome]

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Actinopterygii › Actinopteri › Neopterygii › Teleostei › Elopocephala › Clupeocephala › Otocephala › Ostariophysi › Otophysi › Cypriniphysi › Cypriniformes › Cyprinoidea › Cyprinidae › Danio

Protein attributes

Sequence length	410 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Probable transcription factor involved in the development of the midbrain/hindbrain boundary (MHB) organizer and specification of neuronal cell fates. Required for establishment of eng2 and eng3 gene expression in the midbrain and MHB primordium during late gastrulation. Ref.2
Subcellular location	Nucleus.
Tissue specificity	Expressed during embryogenesis in the kidney, optic stalk, midbrain, otic vesicle and a row of cells along the spinal cord and the hindbrain.
Developmental stage	First seen during the formation of neural keel. At 9-10 hours of development expression seen in two laterally located transverse stripes of cells in the rostral 1/3 of the embryo, and the two areas subsequently move towards the midline and form the posterior portion of the midbrain. Detected in the otic placode, Wolffian duct including the nephritic primordium and optic stalk at 10-12 hours. At 14-15 hours expression seen in the single cells along the spinal cord, presumably interneurons.
Sequence similarities	Contains 1 paired domain.

Ontologies

Keywords
Biological process	Differentiation Neurogenesis Transcription Transcription regulation
Cellular component	Nucleus
Coding sequence diversity	Alternative splicing
Domain	Paired box
Ligand	DNA-binding
Molecular function	Developmental protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cell fate specification Inferred from mutant phenotype PubMed 12917294PubMed 14579372. Source: ZFIN cerebellum formation Inferred from mutant phenotype PubMed 12591239. Source: ZFIN embryonic camera-type eye morphogenesis Inferred from genetic interaction PubMed 19171890. Source: ZFIN embryonic pattern specification Inferred from mutant phenotype PubMed 12889061. Source: ZFIN inner ear receptor cell differentiation Inferred from mutant phenotype PubMed 10572043. Source: ZFIN midbrain development Inferred from mutant phenotype PubMed 12917294PubMed 14579372PubMed 9007239. Source: ZFIN midbrain-hindbrain boundary development Inferred from mutant phenotype PubMed 12591239PubMed 9007239Ref.2. Source: ZFIN otic placode formation Inferred from mutant phenotype PubMed 15459102. Source: ZFIN peripheral nervous system development Inferred from mutant phenotype PubMed 17215310. Source: ZFIN pronephric glomerulus morphogenesis Inferred from mutant phenotype PubMed 22274699. Source: ZFIN pronephros morphogenesis Inferred from mutant phenotype PubMed 22274699. Source: ZFIN thyroid gland development Inferred from mutant phenotype PubMed 14568547PubMed 16680726. Source: ZFIN transcription, DNA-dependent Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	nucleus Non-traceable author statement. Source: UniProtKB
Molecular_function	DNA binding Inferred from direct assay Ref.2. Source: UniProtKB sequence-specific DNA binding transcription factor activity Non-traceable author statement Ref.2. Source: UniProtKB
Complete GO annotation...

Alternative products

This entry describes 12 isoforms produced by alternative splicing. [Align] [Select]

Note: Additional isoforms seem to exist.

Isoform 4 (identifier: Q90268-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 1 (identifier: Q90268-2)

The sequence of this isoform differs from the canonical sequence as follows:
     15-19: LSHIG → R

Isoform 2 (identifier: Q90268-3)

The sequence of this isoform differs from the canonical sequence as follows:
     15-19: LSHIG → R
     209-224: VLWSGNHLDGRKIGYH → D

Isoform 3 (identifier: Q90268-4)

The sequence of this isoform differs from the canonical sequence as follows:
     323-334: GREMASTTLPGY → DKSAGSTVPAGH
     335-410: Missing.

Isoform 5 (identifier: Q90268-5)

The sequence of this isoform differs from the canonical sequence as follows:
     15-19: LSHIG → R
     209-224: VLWSGNHLDGRKIGYH → D
     283-322: Missing.

Isoform 6 (identifier: Q90268-6)

The sequence of this isoform differs from the canonical sequence as follows:
     15-19: LSHIG → R
     209-322: Missing.

Isoform 7 (identifier: Q90268-7)

The sequence of this isoform differs from the canonical sequence as follows:
     15-19: LSHIG → R
     323-334: GREMASTTLPGY → DKSAGSTVPAGH
     335-410: Missing.

Isoform 8 (identifier: Q90268-8)

The sequence of this isoform differs from the canonical sequence as follows:
     386-410: SSPYYYSAASRGSGPPTAATAYDRH → MPHPGAPGLPLLPLPMTAT

Isoform 9 (identifier: Q90268-9)

The sequence of this isoform differs from the canonical sequence as follows:
     209-224: VLWSGNHLDGRKIGYH → D
     386-410: SSPYYYSAASRGSGPPTAATAYDRH → MPHPGAPGLPLLPLPMTAT

Isoform 10 (identifier: Q90268-10)

The sequence of this isoform differs from the canonical sequence as follows:
     15-19: LSHIG → R
     209-224: VLWSGNHLDGRKIGYH → D
     386-410: SSPYYYSAASRGSGPPTAATAYDRH → MPHPGAPGLPLLPLPMTAT

Isoform 11 (identifier: Q90268-11)

The sequence of this isoform differs from the canonical sequence as follows:
     15-19: LSHIG → R
     386-410: SSPYYYSAASRGSGPPTAATAYDRH → MPHPGAPGLPLLPLPMTAT

Isoform 12 (identifier: Q90268-12)

The sequence of this isoform differs from the canonical sequence as follows:
     209-224: VLWSGNHLDGRKIGYH → D

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 410	410	Paired box protein Pax-2a		PRO_0000050177
Regions
	Domain	19 – 145	127	Paired
Natural variations
	Alternative sequence	15 – 19	5	LSHIG → R in isoform 1, isoform 2, isoform 5, isoform 6, isoform 7, isoform 10 and isoform 11.		VSP_002348
	Alternative sequence	209 – 322	114	Missing in isoform 6.		VSP_002350
	Alternative sequence	209 – 224	16	VLWSG…KIGYH → D in isoform 2, isoform 5, isoform 9, isoform 10 and isoform 12.		VSP_002349
	Alternative sequence	283 – 322	40	Missing in isoform 5.		VSP_002351
	Alternative sequence	323 – 334	12	GREMA…TLPGY → DKSAGSTVPAGH in isoform 3 and isoform 7.		VSP_002352
	Alternative sequence	335 – 410	76	Missing in isoform 3 and isoform 7.		VSP_002353
	Alternative sequence	386 – 410	25	SSPYY…AYDRH → MPHPGAPGLPLLPLPMTAT in isoform 8, isoform 9, isoform 10 and isoform 11.		VSP_002354
	Natural variant	74 – 79	6	Missing in allele TM243A; no midbrain/hindbrain boundary.
	Natural variant	79	1	G → V in allele TY31A; no midbrain/hindbrain boundary.

Sequences

	Sequence		Length	Mass (Da)
	Isoform 4 [UniParc]. Last modified May 27, 2002. Version 2. Checksum: 6BE302826C516FD7	FASTA	410	44,099
	10 20 30 40 50 60 MDIHCKADPF SAMHLSHIGH GGVNQLGGVF VNGRPLPDVV RQRIVELAHQ GVRPCDISRQ 70 80 90 100 110 120 LRVSHGCVSK ILGRYYETGS IKPGVIGGSK PKVATPKVVE KIAEYKRQNP TMFAWEIRDR 130 140 150 160 170 180 LLAEGVCDND TVPSVSSINR IIRTKVQQPF HPSSDGTGTP LSTAGHTIVP STASPPVSSA 190 200 210 220 230 240 SNDPVGSYSI NGILGIPRSN GEKRKRDDVL WSGNHLDGRK IGYHGSDGSG PNSDSQGSVE 250 260 270 280 290 300 SLRKHLRADA FTQQQLEALD RVFERPSYPD VFPTSEHIKP EQANEYSLPA LNPGLDEVKP 310 320 330 340 350 360 SLSTSVSSDL GSSVSQSYPV VTGREMASTT LPGYPPHVPP TGQGSYPTST LAGMVPGSDF 370 380 390 400 410 SGNPYSHPQY TTYNEAWRFS NPALLSSPYY YSAASRGSGP PTAATAYDRH
	Isoform 1 [UniParc]. Checksum: 5FA7AE607B8459AA	FASTA	406	43,748
	10 20 30 40 50 60 MDIHCKADPF SAMHRHGGVN QLGGVFVNGR PLPDVVRQRI VELAHQGVRP CDISRQLRVS 70 80 90 100 110 120 HGCVSKILGR YYETGSIKPG VIGGSKPKVA TPKVVEKIAE YKRQNPTMFA WEIRDRLLAE 130 140 150 160 170 180 GVCDNDTVPS VSSINRIIRT KVQQPFHPSS DGTGTPLSTA GHTIVPSTAS PPVSSASNDP 190 200 210 220 230 240 VGSYSINGIL GIPRSNGEKR KRDDVLWSGN HLDGRKIGYH GSDGSGPNSD SQGSVESLRK 250 260 270 280 290 300 HLRADAFTQQ QLEALDRVFE RPSYPDVFPT SEHIKPEQAN EYSLPALNPG LDEVKPSLST 310 320 330 340 350 360 SVSSDLGSSV SQSYPVVTGR EMASTTLPGY PPHVPPTGQG SYPTSTLAGM VPGSDFSGNP 370 380 390 400 YSHPQYTTYN EAWRFSNPAL LSSPYYYSAA SRGSGPPTAA TAYDRH
	Isoform 2 [UniParc]. Checksum: 945AA4986AE92EDB	FASTA	391	42,029
	10 20 30 40 50 60 MDIHCKADPF SAMHRHGGVN QLGGVFVNGR PLPDVVRQRI VELAHQGVRP CDISRQLRVS 70 80 90 100 110 120 HGCVSKILGR YYETGSIKPG VIGGSKPKVA TPKVVEKIAE YKRQNPTMFA WEIRDRLLAE 130 140 150 160 170 180 GVCDNDTVPS VSSINRIIRT KVQQPFHPSS DGTGTPLSTA GHTIVPSTAS PPVSSASNDP 190 200 210 220 230 240 VGSYSINGIL GIPRSNGEKR KRDDDGSDGS GPNSDSQGSV ESLRKHLRAD AFTQQQLEAL 250 260 270 280 290 300 DRVFERPSYP DVFPTSEHIK PEQANEYSLP ALNPGLDEVK PSLSTSVSSD LGSSVSQSYP 310 320 330 340 350 360 VVTGREMAST TLPGYPPHVP PTGQGSYPTS TLAGMVPGSD FSGNPYSHPQ YTTYNEAWRF 370 380 390 SNPALLSSPY YYSAASRGSG PPTAATAYDR H
	Isoform 3 [UniParc]. Checksum: 2BBDAFFEFD23FADA	FASTA	334	35,851
	10 20 30 40 50 60 MDIHCKADPF SAMHLSHIGH GGVNQLGGVF VNGRPLPDVV RQRIVELAHQ GVRPCDISRQ 70 80 90 100 110 120 LRVSHGCVSK ILGRYYETGS IKPGVIGGSK PKVATPKVVE KIAEYKRQNP TMFAWEIRDR 130 140 150 160 170 180 LLAEGVCDND TVPSVSSINR IIRTKVQQPF HPSSDGTGTP LSTAGHTIVP STASPPVSSA 190 200 210 220 230 240 SNDPVGSYSI NGILGIPRSN GEKRKRDDVL WSGNHLDGRK IGYHGSDGSG PNSDSQGSVE 250 260 270 280 290 300 SLRKHLRADA FTQQQLEALD RVFERPSYPD VFPTSEHIKP EQANEYSLPA LNPGLDEVKP 310 320 330 SLSTSVSSDL GSSVSQSYPV VTDKSAGSTV PAGH
	Isoform 5 [UniParc]. Checksum: 8832D34E75D5F0E0	FASTA	351	37,950
	10 20 30 40 50 60 MDIHCKADPF SAMHRHGGVN QLGGVFVNGR PLPDVVRQRI VELAHQGVRP CDISRQLRVS 70 80 90 100 110 120 HGCVSKILGR YYETGSIKPG VIGGSKPKVA TPKVVEKIAE YKRQNPTMFA WEIRDRLLAE 130 140 150 160 170 180 GVCDNDTVPS VSSINRIIRT KVQQPFHPSS DGTGTPLSTA GHTIVPSTAS PPVSSASNDP 190 200 210 220 230 240 VGSYSINGIL GIPRSNGEKR KRDDDGSDGS GPNSDSQGSV ESLRKHLRAD AFTQQQLEAL 250 260 270 280 290 300 DRVFERPSYP DVFPTSEHIK PEQGREMAST TLPGYPPHVP PTGQGSYPTS TLAGMVPGSD 310 320 330 340 350 FSGNPYSHPQ YTTYNEAWRF SNPALLSSPY YYSAASRGSG PPTAATAYDR H
	Isoform 6 [UniParc]. Checksum: 3D86C3147EEBD30A	FASTA	292	31,410
	10 20 30 40 50 60 MDIHCKADPF SAMHRHGGVN QLGGVFVNGR PLPDVVRQRI VELAHQGVRP CDISRQLRVS 70 80 90 100 110 120 HGCVSKILGR YYETGSIKPG VIGGSKPKVA TPKVVEKIAE YKRQNPTMFA WEIRDRLLAE 130 140 150 160 170 180 GVCDNDTVPS VSSINRIIRT KVQQPFHPSS DGTGTPLSTA GHTIVPSTAS PPVSSASNDP 190 200 210 220 230 240 VGSYSINGIL GIPRSNGEKR KRDDGREMAS TTLPGYPPHV PPTGQGSYPT STLAGMVPGS 250 260 270 280 290 DFSGNPYSHP QYTTYNEAWR FSNPALLSSP YYYSAASRGS GPPTAATAYD RH
	Isoform 7 [UniParc]. Checksum: 122C55AA129118F8	FASTA	330	35,500
	10 20 30 40 50 60 MDIHCKADPF SAMHRHGGVN QLGGVFVNGR PLPDVVRQRI VELAHQGVRP CDISRQLRVS 70 80 90 100 110 120 HGCVSKILGR YYETGSIKPG VIGGSKPKVA TPKVVEKIAE YKRQNPTMFA WEIRDRLLAE 130 140 150 160 170 180 GVCDNDTVPS VSSINRIIRT KVQQPFHPSS DGTGTPLSTA GHTIVPSTAS PPVSSASNDP 190 200 210 220 230 240 VGSYSINGIL GIPRSNGEKR KRDDVLWSGN HLDGRKIGYH GSDGSGPNSD SQGSVESLRK 250 260 270 280 290 300 HLRADAFTQQ QLEALDRVFE RPSYPDVFPT SEHIKPEQAN EYSLPALNPG LDEVKPSLST 310 320 330 SVSSDLGSSV SQSYPVVTDK SAGSTVPAGH
	Isoform 8 [UniParc]. Checksum: 6EDC36E73C32675F	FASTA	404	43,377
	10 20 30 40 50 60 MDIHCKADPF SAMHLSHIGH GGVNQLGGVF VNGRPLPDVV RQRIVELAHQ GVRPCDISRQ 70 80 90 100 110 120 LRVSHGCVSK ILGRYYETGS IKPGVIGGSK PKVATPKVVE KIAEYKRQNP TMFAWEIRDR 130 140 150 160 170 180 LLAEGVCDND TVPSVSSINR IIRTKVQQPF HPSSDGTGTP LSTAGHTIVP STASPPVSSA 190 200 210 220 230 240 SNDPVGSYSI NGILGIPRSN GEKRKRDDVL WSGNHLDGRK IGYHGSDGSG PNSDSQGSVE 250 260 270 280 290 300 SLRKHLRADA FTQQQLEALD RVFERPSYPD VFPTSEHIKP EQANEYSLPA LNPGLDEVKP 310 320 330 340 350 360 SLSTSVSSDL GSSVSQSYPV VTGREMASTT LPGYPPHVPP TGQGSYPTST LAGMVPGSDF 370 380 390 400 SGNPYSHPQY TTYNEAWRFS NPALLMPHPG APGLPLLPLP MTAT
	Isoform 9 [UniParc]. Checksum: 37B68840DF11B472	FASTA	389	41,658
	10 20 30 40 50 60 MDIHCKADPF SAMHLSHIGH GGVNQLGGVF VNGRPLPDVV RQRIVELAHQ GVRPCDISRQ 70 80 90 100 110 120 LRVSHGCVSK ILGRYYETGS IKPGVIGGSK PKVATPKVVE KIAEYKRQNP TMFAWEIRDR 130 140 150 160 170 180 LLAEGVCDND TVPSVSSINR IIRTKVQQPF HPSSDGTGTP LSTAGHTIVP STASPPVSSA 190 200 210 220 230 240 SNDPVGSYSI NGILGIPRSN GEKRKRDDDG SDGSGPNSDS QGSVESLRKH LRADAFTQQQ 250 260 270 280 290 300 LEALDRVFER PSYPDVFPTS EHIKPEQANE YSLPALNPGL DEVKPSLSTS VSSDLGSSVS 310 320 330 340 350 360 QSYPVVTGRE MASTTLPGYP PHVPPTGQGS YPTSTLAGMV PGSDFSGNPY SHPQYTTYNE 370 380 AWRFSNPALL MPHPGAPGLP LLPLPMTAT
	Isoform 10 [UniParc]. Checksum: 2FD08B99DB3FD5DF	FASTA	385	41,306
	10 20 30 40 50 60 MDIHCKADPF SAMHRHGGVN QLGGVFVNGR PLPDVVRQRI VELAHQGVRP CDISRQLRVS 70 80 90 100 110 120 HGCVSKILGR YYETGSIKPG VIGGSKPKVA TPKVVEKIAE YKRQNPTMFA WEIRDRLLAE 130 140 150 160 170 180 GVCDNDTVPS VSSINRIIRT KVQQPFHPSS DGTGTPLSTA GHTIVPSTAS PPVSSASNDP 190 200 210 220 230 240 VGSYSINGIL GIPRSNGEKR KRDDDGSDGS GPNSDSQGSV ESLRKHLRAD AFTQQQLEAL 250 260 270 280 290 300 DRVFERPSYP DVFPTSEHIK PEQANEYSLP ALNPGLDEVK PSLSTSVSSD LGSSVSQSYP 310 320 330 340 350 360 VVTGREMAST TLPGYPPHVP PTGQGSYPTS TLAGMVPGSD FSGNPYSHPQ YTTYNEAWRF 370 380 SNPALLMPHP GAPGLPLLPL PMTAT
	Isoform 11 [UniParc]. Checksum: C8A1151F0D5C4610	FASTA	400	43,025
	10 20 30 40 50 60 MDIHCKADPF SAMHRHGGVN QLGGVFVNGR PLPDVVRQRI VELAHQGVRP CDISRQLRVS 70 80 90 100 110 120 HGCVSKILGR YYETGSIKPG VIGGSKPKVA TPKVVEKIAE YKRQNPTMFA WEIRDRLLAE 130 140 150 160 170 180 GVCDNDTVPS VSSINRIIRT KVQQPFHPSS DGTGTPLSTA GHTIVPSTAS PPVSSASNDP 190 200 210 220 230 240 VGSYSINGIL GIPRSNGEKR KRDDVLWSGN HLDGRKIGYH GSDGSGPNSD SQGSVESLRK 250 260 270 280 290 300 HLRADAFTQQ QLEALDRVFE RPSYPDVFPT SEHIKPEQAN EYSLPALNPG LDEVKPSLST 310 320 330 340 350 360 SVSSDLGSSV SQSYPVVTGR EMASTTLPGY PPHVPPTGQG SYPTSTLAGM VPGSDFSGNP 370 380 390 400 YSHPQYTTYN EAWRFSNPAL LMPHPGAPGL PLLPLPMTAT
	Isoform 12 [UniParc]. Checksum: 9629926611BDC6BD	FASTA	395	42,380
	10 20 30 40 50 60 MDIHCKADPF SAMHLSHIGH GGVNQLGGVF VNGRPLPDVV RQRIVELAHQ GVRPCDISRQ 70 80 90 100 110 120 LRVSHGCVSK ILGRYYETGS IKPGVIGGSK PKVATPKVVE KIAEYKRQNP TMFAWEIRDR 130 140 150 160 170 180 LLAEGVCDND TVPSVSSINR IIRTKVQQPF HPSSDGTGTP LSTAGHTIVP STASPPVSSA 190 200 210 220 230 240 SNDPVGSYSI NGILGIPRSN GEKRKRDDDG SDGSGPNSDS QGSVESLRKH LRADAFTQQQ 250 260 270 280 290 300 LEALDRVFER PSYPDVFPTS EHIKPEQANE YSLPALNPGL DEVKPSLSTS VSSDLGSSVS 310 320 330 340 350 360 QSYPVVTGRE MASTTLPGYP PHVPPTGQGS YPTSTLAGMV PGSDFSGNPY SHPQYTTYNE 370 380 390 AWRFSNPALL SSPYYYSAAS RGSGPPTAAT AYDRH

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Expression of the zebrafish paired box gene pax[zf-b] during early neurogenesis." Krauss S., Johansen T., Korzh V., Fjose A. Development 113:1193-1206(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2). Strain: NC-1. Tissue: Embryo.
[2]	"A series of no isthmus (noi) alleles of the zebrafish pax2.1 gene reveals multiple signaling events in development of the midbrain-hindbrain boundary." Lun K., Brand M. Development 125:3049-3062(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], ALTERNATIVE SPLICING, VARIANTS, FUNCTION. Strain: Tuebingen. Tissue: Embryo.
[3]	NIH - Zebrafish Gene Collection (ZGC) project Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Kidney.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X63961 mRNA. Translation: CAA45378.1. AF067530 mRNA. Translation: AAD19285.1. AF067531 mRNA. Translation: AAD19286.1. AF067532 mRNA. Translation: AAD19287.1. AF067533 mRNA. Translation: AAD19288.1. AF067534 mRNA. Translation: AAD19289.1. AF067535 mRNA. Translation: AAD19290.1. AF067536 mRNA. Translation: AAD19291.1. AF067537 mRNA. Translation: AAD19292.1. AF067538 mRNA. Translation: AAD19293.1. AF067539 mRNA. Translation: AAD19294.1. AF067540 mRNA. Translation: AAD19295.1. AF067541 mRNA. Translation: AAD19296.1. BC066690 mRNA. Translation: AAH66690.1.
IPI	IPI00483022. IPI00491072. IPI00494276. IPI00496561. IPI00498555. IPI00504315. IPI00505213. IPI00509133. IPI00509801. IPI00832225. IPI00923245. IPI00972778.
PIR	S23341.
RefSeq	NP_571259.1. NM_131184.2.
UniGene	Dr.75076.
3D structure databases
ProteinModelPortal	Q90268.
SMR	Q90268. Positions 22-145.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000076998; ENSDARP00000071466; ENSDARG00000028148. ENSDART00000134424; ENSDARP00000121417; ENSDARG00000028148.
GeneID	30425.
KEGG	dre:30425.
Organism-specific databases
CTD	30425.
ZFIN	ZDB-GENE-990415-8. pax2a.
Phylogenomic databases
eggNOG	NOG326044.
GeneTree	ENSGT00680000099910.
HOVERGEN	HBG009115.
InParanoid	Q90268.
KO	K15608.
Gene expression databases
ArrayExpress	Q90268.
Bgee	Q90268.
Family and domain databases
Gene3D	1.10.10.10. 2 hits.
InterPro	IPR009057. Homeodomain-like. IPR001523. Paired_dom. IPR022130. Pax2_C. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
Pfam	PF00292. PAX. 1 hit. PF12403. Pax2_C. 1 hit. [Graphical view]
PRINTS	PR00027. PAIREDBOX.
SMART	SM00351. PAX. 1 hit. [Graphical view]
SUPFAM	SSF46689. Homeodomain_like. 1 hit.
PROSITE	PS00034. PAIRED_1. 1 hit. PS51057. PAIRED_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20806828.

Entry information

Entry name

PAX2A_DANRE

Accession

Primary (citable) accession number: Q90268
Secondary accession number(s): Q9PWK8 , Q9PWK9, Q9PWL0, Q9PWL1, Q9YGU5, Q9YGU6, Q9YGU7, Q9YGU8, Q9YGU9, Q9YGV0

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	May 27, 2002
Last modified:	May 1, 2013
This is version 107 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program