Q90187 (CAPSD_AADNV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Capsid protein VP1/VP2

Alternative name(s):
Coat protein VP1/VP2

Gene names

Name:

VP

Organism

Aedes albopictus densovirus (isolate Boublik/1994) (AalDNV)

Taxonomic identifier

648330 [NCBI]

Taxonomic lineage

Viruses › ssDNA viruses › Parvoviridae › Densovirinae › Brevidensovirus

Virus host

Aedes albopictus (Asian tiger mosquito) (Culex albopictus) [TaxID: 7160]

Protein attributes

Sequence length	355 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 22 nm in diameter, and consisting of 60 copies of size variants of the capsid proteins, which differ in the N-terminushe capsid encapsulates the genomic ssDNA. Capsid proteins are responsible for the attachment to host cell receptors. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis By similarity. Ref.2
Subcellular location	Virion Potential.
Sequence similarities	Belongs to the parvoviridae capsid protein family.
Sequence caution	The sequence CAA52901.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Clathrin-mediated endocytosis of virus by host Host-virus interaction Initiation of viral infection Viral attachment to host cell Viral penetration into host cytoplasm Viral penetration via permeabilization of host organellar membrane Virus endocytosis by host
Cellular component	Virion
Coding sequence diversity	Alternative initiation
Molecular function	Capsid protein T=1 icosahedral capsid protein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	interspecies interaction between organisms Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	viral capsid Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative initiation. [Select]

Isoform VP1 (identifier: Q90187-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform VP2 (identifier: Q90187-2)

The sequence of this isoform is not available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 355	355	Capsid protein VP1/VP2		PRO_0000039443

Sequences

	Sequence		Length	Mass (Da)
	Isoform VP1 [UniParc]. Last modified July 15, 1999. Version 2. Checksum: F662F6F56CD2A7F1	FASTA	355	40,942
	10 20 30 40 50 60 MADSTTMEHD GRGTKRKREA DGGSGQGVGK GNSNAVKEGY GPNITEMVPR NIFNKGNHTI 70 80 90 100 110 120 YHVVKTQKYL DFNYVTNQNP YIIPYQTAGF WGSMWDQTDI GNNQSINIMK ALNAVALGVT 130 140 150 160 170 180 WIKGEITFEV YSVTRQRLLT GTTNQTTWDF ETSQNMFIAD ADREPENFNL ETVAATGPLA 190 200 210 220 230 240 QQTTQTLLFN SHNDRYTKYE LPQRNQYTRE INFQQLTNNY MWRPLDISKE TNFRSLIPMS 250 260 270 280 290 300 EGVYTKSENL RQTEFTYETT TYATSGATTR QTLFRNRTSY PRMHIAQPQV PDETGFMKFR 310 320 330 340 350 YQVRMSTKLH LNFHMYPDYA TNNNLEYMHR QTILLPQVAE TNGIVACMPY EINTQ
	Isoform VP2 (Sequence not available).		–	–

References

[1]	"Complete nucleotide sequence and genomic organization of the Aedes albopictus parvovirus (AaPV) pathogenic for Aedes aegypti larvae." Boublik Y., Jousset F.X., Bergoin M. Virology 200:752-763(1994) [PubMed: 8178459] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Structure comparisons of Aedes albopictus densovirus with other parvoviruses." Cheng L., Chen S., Zhou Z.H., Zhang J. Sci. China, Ser. C, Life Sci. 50:70-74(2007) [PubMed: 17393085] [Abstract] Cited for: FUNCTION. Strain: Aedes albopictus C6/36 cell densovirus.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X74945 Genomic DNA. Translation: CAA52901.1. Different initiation.
RefSeq	NP_694829.2. NC_004285.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	955418.
Family and domain databases
ProtoNet	Search...

Entry information

Entry name

CAPSD_AADNV

Accession

Primary (citable) accession number: Q90187

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1999
Last sequence update:	July 15, 1999
Last modified:	September 21, 2011
This is version 47 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program