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Q8ZYX0

- UPPP_PYRAE

UniProt

Q8ZYX0 - UPPP_PYRAE

Protein

Undecaprenyl-diphosphatase

Gene

uppP

Organism
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (05 Mar 2002)
      Previous versions | rss
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    Functioni

    Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP).UniRule annotation

    Catalytic activityi

    Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate.UniRule annotation

    GO - Molecular functioni

    1. sodium:dicarboxylate symporter activity Source: InterPro
    2. undecaprenyl-diphosphatase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. dephosphorylation Source: InterPro

    Keywords - Molecular functioni

    Hydrolase

    Enzyme and pathway databases

    BioCyciPAER178306:GCEO-388-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Undecaprenyl-diphosphataseUniRule annotation (EC:3.6.1.27UniRule annotation)
    Alternative name(s):
    Undecaprenyl pyrophosphate phosphataseUniRule annotation
    Gene namesi
    Name:uppPUniRule annotation
    Synonyms:bacA, upk
    Ordered Locus Names:PAE0576
    OrganismiPyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
    Taxonomic identifieri178306 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
    ProteomesiUP000002439: Chromosome

    Subcellular locationi

    Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 266266Undecaprenyl-diphosphatasePRO_0000151253Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi178306.PAE0576.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8ZYX0.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei41 – 6121HelicalUniRule annotationAdd
    BLAST
    Transmembranei82 – 10221HelicalUniRule annotationAdd
    BLAST
    Transmembranei106 – 12621HelicalUniRule annotationAdd
    BLAST
    Transmembranei159 – 17921HelicalUniRule annotationAdd
    BLAST
    Transmembranei191 – 21121HelicalUniRule annotationAdd
    BLAST
    Transmembranei213 – 23321HelicalUniRule annotationAdd
    BLAST
    Transmembranei246 – 26621HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UppP family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1968.
    HOGENOMiHOG000218357.
    KOiK06153.
    OMAiEFRENEE.

    Family and domain databases

    HAMAPiMF_01006. Undec_diphosphatase.
    InterProiIPR001991. Na-dicarboxylate_symporter.
    IPR003824. UppP.
    [Graphical view]
    PfamiPF02673. BacA. 1 hit.
    [Graphical view]
    PRINTSiPR00173. EDTRNSPORT.

    Sequencei

    Sequence statusi: Complete.

    Q8ZYX0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDLGVAAILG VVQGISEWLP ISSKTQIMLV SIWLLNASPE YAYSLGLFLE    50
    AASVLAALIY FRGVYLKALR GFVGDAEGRR WLVYILVTTL VTAVVGLPLY 100
    YVARKWLVVG HSAGFLMIVL GLAVVLNAVF LQRARFSAGL KAFDNMSLRD 150
    MAIVGIAQAV SVLPGLSRSG ATVTALLLLG YKPEEAFRAS FVLVPVAGLG 200
    ATALAYLSEG GAVATAEALL AMAIGIVISI ITIKALLEFA KSKHVVLVNV 250
    VIGLLAIAGG LLRIIF 266
    Length:266
    Mass (Da):28,045
    Last modified:March 5, 2002 - v1
    Checksum:i2D2A623EDBB43987
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE009441 Genomic DNA. Translation: AAL62872.1.
    RefSeqiNP_558690.1. NC_003364.1.
    WP_011007344.1. NC_003364.1.

    Genome annotation databases

    EnsemblBacteriaiAAL62872; AAL62872; PAE0576.
    GeneIDi1465095.
    KEGGipai:PAE0576.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE009441 Genomic DNA. Translation: AAL62872.1 .
    RefSeqi NP_558690.1. NC_003364.1.
    WP_011007344.1. NC_003364.1.

    3D structure databases

    ProteinModelPortali Q8ZYX0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 178306.PAE0576.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL62872 ; AAL62872 ; PAE0576 .
    GeneIDi 1465095.
    KEGGi pai:PAE0576.

    Phylogenomic databases

    eggNOGi COG1968.
    HOGENOMi HOG000218357.
    KOi K06153.
    OMAi EFRENEE.

    Enzyme and pathway databases

    BioCyci PAER178306:GCEO-388-MONOMER.

    Family and domain databases

    HAMAPi MF_01006. Undec_diphosphatase.
    InterProi IPR001991. Na-dicarboxylate_symporter.
    IPR003824. UppP.
    [Graphical view ]
    Pfami PF02673. BacA. 1 hit.
    [Graphical view ]
    PRINTSi PR00173. EDTRNSPORT.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum."
      Fitz-Gibbon S.T., Ladner H., Kim U.-J., Stetter K.O., Simon M.I., Miller J.H.
      Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827.

    Entry informationi

    Entry nameiUPPP_PYRAE
    AccessioniPrimary (citable) accession number: Q8ZYX0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 5, 2002
    Last sequence update: March 5, 2002
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3