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Q8ZYX0 (UPPP_PYRAE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase
EC=3.6.1.27
Alternative name(s):
Undecaprenyl pyrophosphate phosphatase
Gene names
Name:uppP
Synonyms:bacA, upk
Ordered Locus Names:PAE0576
OrganismPyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827) [Reference proteome] [HAMAP]
Taxonomic identifier178306 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Thermoproteales › Thermoproteaceae › Pyrobaculum ›

Protein attributes

Sequence length266 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Sequence similarities

Belongs to the UppP family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionHydrolase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processdephosphorylation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionsodium:dicarboxylate symporter activity

Inferred from electronic annotation. Source: InterPro

undecaprenyl-diphosphatase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 266266Undecaprenyl-diphosphatase HAMAP-Rule MF_01006
PRO_0000151253

Regions

Transmembrane41 – 6121Helical; Potential
Transmembrane82 – 10221Helical; Potential
Transmembrane106 – 12621Helical; Potential
Transmembrane159 – 17921Helical; Potential
Transmembrane191 – 21121Helical; Potential
Transmembrane213 – 23321Helical; Potential
Transmembrane246 – 26621Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q8ZYX0 [UniParc].

Last modified March 5, 2002. Version 1.
Checksum: 2D2A623EDBB43987

FASTA26628,045
        10         20         30         40         50         60 
MDLGVAAILG VVQGISEWLP ISSKTQIMLV SIWLLNASPE YAYSLGLFLE AASVLAALIY 

        70         80         90        100        110        120 
FRGVYLKALR GFVGDAEGRR WLVYILVTTL VTAVVGLPLY YVARKWLVVG HSAGFLMIVL 

       130        140        150        160        170        180 
GLAVVLNAVF LQRARFSAGL KAFDNMSLRD MAIVGIAQAV SVLPGLSRSG ATVTALLLLG 

       190        200        210        220        230        240 
YKPEEAFRAS FVLVPVAGLG ATALAYLSEG GAVATAEALL AMAIGIVISI ITIKALLEFA 

       250        260 
KSKHVVLVNV VIGLLAIAGG LLRIIF

« Hide

References

[1]"Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum."
Fitz-Gibbon S.T., Ladner H., Kim U.-J., Stetter K.O., Simon M.I., Miller J.H.
Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE009441 Genomic DNA. Translation: AAL62872.1.
RefSeqNP_558690.1. NC_003364.1.

3D structure databases

ProteinModelPortalQ8ZYX0.
ModBaseSearch...

Protein-protein interaction databases

STRING178306.PAE0576.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL62872; AAL62872; PAE0576.
GeneID1465095.
KEGGpai:PAE0576.

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAYIFVASI.
ProtClustDBPRK00281.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. Bacitracin-R_BacA.
IPR001991. Na-dicarboxylate_symporter.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
PRINTSPR00173. EDTRNSPORT.
ProtoNetSearch...

Entry information

Entry nameUPPP_PYRAE
AccessionPrimary (citable) accession number: Q8ZYX0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: March 5, 2002
Last modified: May 1, 2013
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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