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Q8ZYX0

- UPPP_PYRAE

UniProt

Q8ZYX0 - UPPP_PYRAE

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Protein
Undecaprenyl-diphosphatase
Gene
uppP, bacA, upk, PAE0576
Organism
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) By similarity.UniRule annotation

Catalytic activityi

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate.UniRule annotation

GO - Molecular functioni

  1. sodium:dicarboxylate symporter activity Source: InterPro
  2. undecaprenyl-diphosphatase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. dephosphorylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciPAER178306:GCEO-388-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Undecaprenyl-diphosphatase (EC:3.6.1.27)
Alternative name(s):
Undecaprenyl pyrophosphate phosphatase
Gene namesi
Name:uppP
Synonyms:bacA, upk
Ordered Locus Names:PAE0576
OrganismiPyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Taxonomic identifieri178306 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
ProteomesiUP000002439: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei41 – 6121Helical; Reviewed prediction
Add
BLAST
Transmembranei82 – 10221Helical; Reviewed prediction
Add
BLAST
Transmembranei106 – 12621Helical; Reviewed prediction
Add
BLAST
Transmembranei159 – 17921Helical; Reviewed prediction
Add
BLAST
Transmembranei191 – 21121Helical; Reviewed prediction
Add
BLAST
Transmembranei213 – 23321Helical; Reviewed prediction
Add
BLAST
Transmembranei246 – 26621Helical; Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 266266Undecaprenyl-diphosphataseUniRule annotation
PRO_0000151253Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi178306.PAE0576.

Structurei

3D structure databases

ProteinModelPortaliQ8ZYX0.

Family & Domainsi

Sequence similaritiesi

Belongs to the UppP family.

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1968.
HOGENOMiHOG000218357.
KOiK06153.
OMAiEFRENEE.

Family and domain databases

HAMAPiMF_01006. Undec_diphosphatase.
InterProiIPR001991. Na-dicarboxylate_symporter.
IPR003824. UppP.
[Graphical view]
PfamiPF02673. BacA. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.

Sequencei

Sequence statusi: Complete.

Q8ZYX0-1 [UniParc]FASTAAdd to Basket

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MDLGVAAILG VVQGISEWLP ISSKTQIMLV SIWLLNASPE YAYSLGLFLE    50
AASVLAALIY FRGVYLKALR GFVGDAEGRR WLVYILVTTL VTAVVGLPLY 100
YVARKWLVVG HSAGFLMIVL GLAVVLNAVF LQRARFSAGL KAFDNMSLRD 150
MAIVGIAQAV SVLPGLSRSG ATVTALLLLG YKPEEAFRAS FVLVPVAGLG 200
ATALAYLSEG GAVATAEALL AMAIGIVISI ITIKALLEFA KSKHVVLVNV 250
VIGLLAIAGG LLRIIF 266
Length:266
Mass (Da):28,045
Last modified:March 5, 2002 - v1
Checksum:i2D2A623EDBB43987
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009441 Genomic DNA. Translation: AAL62872.1.
RefSeqiNP_558690.1. NC_003364.1.
WP_011007344.1. NC_003364.1.

Genome annotation databases

EnsemblBacteriaiAAL62872; AAL62872; PAE0576.
GeneIDi1465095.
KEGGipai:PAE0576.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009441 Genomic DNA. Translation: AAL62872.1 .
RefSeqi NP_558690.1. NC_003364.1.
WP_011007344.1. NC_003364.1.

3D structure databases

ProteinModelPortali Q8ZYX0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 178306.PAE0576.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL62872 ; AAL62872 ; PAE0576 .
GeneIDi 1465095.
KEGGi pai:PAE0576.

Phylogenomic databases

eggNOGi COG1968.
HOGENOMi HOG000218357.
KOi K06153.
OMAi EFRENEE.

Enzyme and pathway databases

BioCyci PAER178306:GCEO-388-MONOMER.

Family and domain databases

HAMAPi MF_01006. Undec_diphosphatase.
InterProi IPR001991. Na-dicarboxylate_symporter.
IPR003824. UppP.
[Graphical view ]
Pfami PF02673. BacA. 1 hit.
[Graphical view ]
PRINTSi PR00173. EDTRNSPORT.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum."
    Fitz-Gibbon S.T., Ladner H., Kim U.-J., Stetter K.O., Simon M.I., Miller J.H.
    Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827.

Entry informationi

Entry nameiUPPP_PYRAE
AccessioniPrimary (citable) accession number: Q8ZYX0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: March 5, 2002
Last modified: September 3, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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