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Protein

DNA-directed RNA polymerase subunit A''

Gene

rpoA2

Organism
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.UniRule annotation

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit A''UniRule annotation (EC:2.7.7.6UniRule annotation)
Gene namesi
Name:rpoA2UniRule annotation
Ordered Locus Names:PAE0667
OrganismiPyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Taxonomic identifieri178306 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
Proteomesi
  • UP000002439 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000740211 – 379DNA-directed RNA polymerase subunit A''Add BLAST379

Interactioni

Protein-protein interaction databases

STRINGi178306.PAE0667.

Structurei

3D structure databases

ProteinModelPortaliQ8ZYQ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta' chain family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG04256. Archaea.
COG0086. LUCA.
HOGENOMiHOG000222986.
InParanoidiQ8ZYQ7.
KOiK03042.
OMAiRPIGRHG.

Family and domain databases

CDDicd06528. RNAP_A''. 1 hit.
HAMAPiMF_00411. RNApol_arch_A. 1 hit.
InterProiIPR007081. RNA_pol_Rpb1_5.
IPR012757. RNAP_A2.
[Graphical view]
PfamiPF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02389. RNA_pol_rpoA2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8ZYQ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MISREELLSK LSQVLPQPLY KEVEEAVRDL DDEKALRLVY RVLKLYVTSL
60 70 80 90 100
IDPGEAIGIV TAQSIGEPGT QMILRSFHYA GLREFSMARG LPRLIEVVDA
110 120 130 140 150
RRTPSTPLMY VYLKPPYNKS REAAESVAKK IQQVTLETLA KEVDVDYVAG
160 170 180 190 200
TVTITLDQEQ LKYRGLTLKD VEKIVAKAKG KDVAISMRGY TITASLTTPD
210 220 230 240 250
ILKIRKIKDK ILQIKISGIK GVRKVVLQYD SKNDEWYIVT EGTNLEAVLQ
260 270 280 290 300
LEEVDPTRTY SNDLHEVEEV LGIEATRALV AQEIKRVLEE QGLDVDIRHM
310 320 330 340 350
YLVADAMTWS GRLRPIGRHG VVGSKESPLA RAAFEVTVKT LIEASVRGED
360 370
ELFKGVVESI IAGKYVPIGT GIVRLLMQF
Length:379
Mass (Da):42,423
Last modified:March 1, 2002 - v1
Checksum:iA9091297A5B37C9B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009441 Genomic DNA. Translation: AAL62936.1.

Genome annotation databases

EnsemblBacteriaiAAL62936; AAL62936; PAE0667.
KEGGipai:PAE0667.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009441 Genomic DNA. Translation: AAL62936.1.

3D structure databases

ProteinModelPortaliQ8ZYQ7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi178306.PAE0667.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL62936; AAL62936; PAE0667.
KEGGipai:PAE0667.

Phylogenomic databases

eggNOGiarCOG04256. Archaea.
COG0086. LUCA.
HOGENOMiHOG000222986.
InParanoidiQ8ZYQ7.
KOiK03042.
OMAiRPIGRHG.

Family and domain databases

CDDicd06528. RNAP_A''. 1 hit.
HAMAPiMF_00411. RNApol_arch_A. 1 hit.
InterProiIPR007081. RNA_pol_Rpb1_5.
IPR012757. RNAP_A2.
[Graphical view]
PfamiPF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02389. RNA_pol_rpoA2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRPOA2_PYRAE
AccessioniPrimary (citable) accession number: Q8ZYQ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2002
Last sequence update: March 1, 2002
Last modified: November 2, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.