Q8ZXK6 (ACYP_PYRAE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Acylphosphatase
EC=3.6.1.7

Alternative name(s):
Acylphosphate phosphohydrolase

Gene names

Name:	acyP
Ordered Locus Names:	PAE1232

Organism

Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)

Taxonomic identifier

178306 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Thermoproteales › Thermoproteaceae › Pyrobaculum

Protein attributes

Sequence length	95 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	An acylphosphate + H2O = a carboxylate + phosphate. HAMAP MF_01450
Sequence similarities	Belongs to the acylphosphatase family. Contains 1 acylphosphatase-like domain.

Ontologies

Keywords
Molecular function	Hydrolase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	acylphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 95	95	Acylphosphatase HAMAP MF_01450		PRO_0000326865
Regions
	Domain	5 – 93	89	Acylphosphatase-like
Sites
	Active site	20	1	By similarity
	Active site	38	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q8ZXK6 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: E2A63BEF93CF7C80	FASTA	95	10,921
	10 20 30 40 50 60 MEMARAHVFI RGKVQGVFFR QSMKEVAMRN GVKGWVRNRS DGKTVEAVLE GPRDAVMKVL 70 80 90 EWARIGPPGA RVEDIEVQWE EYKGEFKDFK ILPTV

References

[1]	"Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum." Fitz-Gibbon S.T., Ladner H., Kim U.-J., Stetter K.O., Simon M.I., Miller J.H. Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002) [PubMed: 11792869] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE009441 Genomic DNA. Translation: AAL63341.1.
RefSeq	NP_559159.1. NC_003364.1.
3D structure databases
HSSP	HSSP built from PDB template 1W2I based on UniProtKB P84142.
ProteinModelPortal	Q8ZXK6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1465579.
GenomeReviews	Gene locus PAE1232 in contig AE009441_GR.
KEGG	pai:PAE1232.
NMPDR	fig|178306.1.peg.849.
Phylogenomic databases
HOGENOM	HBG750266.
OMA	WCHTGSP.
ProtClustDB	PRK14447.
Enzyme and pathway databases
BioCyc	PAER178306:PAE1232-MONOMER.
Family and domain databases
HAMAP	MF_01450. Acylphosphatase. [Tree]
InterPro	IPR001792. Acylphosphatase-like. IPR017968. Acylphosphatase_CS. [Graphical view]
KO	K01512.
Pfam	PF00708. Acylphosphatase. 1 hit. [Graphical view]
SUPFAM	SSF54975. Acylphosphatase. 1 hit.
PROSITE	PS00150. ACYLPHOSPHATASE_1. 1 hit. PS00151. ACYLPHOSPHATASE_2. False negative. PS51160. ACYLPHOSPHATASE_3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ACYP_PYRAE

Accession

Primary (citable) accession number: Q8ZXK6

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 8, 2008
Last sequence update:	March 1, 2002
Last modified:	November 16, 2011
This is version 54 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program