Q8ZVE4 (APGM_PYRAE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=aPGAM
EC=5.4.2.1

Gene names

Name:	apgM
Ordered Locus Names:	PAE2326

Organism

Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)

Taxonomic identifier

178306 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Thermoproteales › Thermoproteaceae › Pyrobaculum

Protein attributes

Sequence length	411 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402_A
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402_A
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402_A
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: InterPro phosphoglycerate mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 411	411	2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402_A		PRO_0000138143

Sequences

	Sequence		Length	Mass (Da)
	Q8ZVE4 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: E902852B8DC8AC96	FASTA	411	44,865
	10 20 30 40 50 60 MPSVLWVLFD GGADRPVGRK TPFYVAFKPT IDYLSSLGSC GMLDPISPGI RPGSDTAHLA 70 80 90 100 110 120 LFGYDPYKYY TGRGAFEALG ADVALKPGDV AFRTNLATVD EAGVVIDRRA GRYIAPEEAR 130 140 150 160 170 180 SVEEVINKIG EEIGKKYGVD VFYKSTVEHR GVLVIRGPVS HRVSDTDPHR VGAKILRSEP 190 200 210 220 230 240 LERSKEAALT AEVVNEITLR FMEISKELEI NKARRLQGKL PINAILLRGG GYMPQIEPIR 250 260 270 280 290 300 EKYNIRAAAI AGVALIRGVA RAVGMDVYTA PGLGGTKDDV FDQAVKLAVE LMSKYDVVFL 310 320 330 340 350 360 HVKGTDSTSH DGDFNGKVSV IERLDKALAP YLDKLLNNYF VVTSDHATPV SVKEHTGEPV 370 380 390 400 410 PILLYGPDVV QDDVSKFSEL TCWRGALGRI RGIDVMPILG SYLGLTEKFG E

References

[1]

"Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum." Fitz-Gibbon S.T., Ladner H., Kim U.-J., Stetter K.O., Simon M.I., Miller J.H. Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002) [PubMed: 11792869] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE009441 Genomic DNA. Translation: AAL64112.1.
RefSeq	NP_559930.1. NC_003364.1.
3D structure databases
ProteinModelPortal	Q8ZVE4.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1464448.
GenomeReviews	Gene locus PAE2326 in contig AE009441_GR.
KEGG	pai:PAE2326.
NMPDR	fig|178306.1.peg.1620.
Phylogenomic databases
HOGENOM	HBG463247.
OMA	DIAFRCN.
ProtClustDB	PRK04024.
Enzyme and pathway databases
BioCyc	PAER178306:PAE2326-MONOMER.
Family and domain databases
HAMAP	MF_01402_A. ApgM_A. [Tree]
InterPro	IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR023665. ApgAM. IPR004456. BisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Gene3D	G3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KO	K15635.
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
SUPFAM	SSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMs	TIGR00306. ApgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM_PYRAE

Accession

Primary (citable) accession number: Q8ZVE4

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 2, 2002
Last sequence update:	March 1, 2002
Last modified:	January 25, 2012
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program