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Q8ZV18

- TRPF_PYRAE

UniProt

Q8ZV18 - TRPF_PYRAE

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Protein
N-(5'-phosphoribosyl)anthranilate isomerase
Gene
trpF, PAE2499
Organism
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. phosphoribosylanthranilate isomerase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. tryptophan biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Amino-acid biosynthesis, Aromatic amino acid biosynthesis, Tryptophan biosynthesis

Enzyme and pathway databases

BioCyciPAER178306:GCEO-1806-MONOMER.
UniPathwayiUPA00035; UER00042.

Names & Taxonomyi

Protein namesi
Recommended name:
N-(5'-phosphoribosyl)anthranilate isomerase (EC:5.3.1.24)
Short name:
PRAI
Gene namesi
Name:trpF
Ordered Locus Names:PAE2499
OrganismiPyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Taxonomic identifieri178306 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
ProteomesiUP000002439: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 208208N-(5'-phosphoribosyl)anthranilate isomeraseUniRule annotation
PRO_0000154411Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi178306.PAE2499.

Structurei

3D structure databases

ProteinModelPortaliQ8ZV18.

Family & Domainsi

Sequence similaritiesi

Belongs to the TrpF family.

Phylogenomic databases

eggNOGiCOG0135.
HOGENOMiHOG000161598.
KOiK01817.
OMAiPYMIDVA.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_00135. PRAI.
InterProiIPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00697. PRAI. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.

Sequencei

Sequence statusi: Complete.

Q8ZV18-1 [UniParc]FASTAAdd to Basket

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MVLVKICGVV RVEDAVLLDG VADYIGFIVE PTSPRSVKPE ALRSLRDAVI    50
KSRPVLVTAT IPPKEAVDIA AKNEIPVVQY HSTLAPKDFD YAETRGVTLA 100
PVAVYKPGIE LKQLVEELLK TPHEYVLVDA DKKSQERYEG GLKIPLTLLA 150
EVAPLGRVAL AGGITPENAQ LIARLNPYMI DVASGVEASP GVKDMNKVKA 200
LLKAVGRL 208
Length:208
Mass (Da):22,396
Last modified:March 1, 2002 - v1
Checksum:i418E1F65158B024C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009441 Genomic DNA. Translation: AAL64238.1.
RefSeqiNP_560056.1. NC_003364.1.
WP_011008706.1. NC_003364.1.

Genome annotation databases

EnsemblBacteriaiAAL64238; AAL64238; PAE2499.
GeneIDi1464579.
KEGGipai:PAE2499.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE009441 Genomic DNA. Translation: AAL64238.1 .
RefSeqi NP_560056.1. NC_003364.1.
WP_011008706.1. NC_003364.1.

3D structure databases

ProteinModelPortali Q8ZV18.
ModBasei Search...

Protein-protein interaction databases

STRINGi 178306.PAE2499.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL64238 ; AAL64238 ; PAE2499 .
GeneIDi 1464579.
KEGGi pai:PAE2499.

Phylogenomic databases

eggNOGi COG0135.
HOGENOMi HOG000161598.
KOi K01817.
OMAi PYMIDVA.

Enzyme and pathway databases

UniPathwayi UPA00035 ; UER00042 .
BioCyci PAER178306:GCEO-1806-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_00135. PRAI.
InterProi IPR013785. Aldolase_TIM.
IPR001240. PRAI_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00697. PRAI. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum."
    Fitz-Gibbon S.T., Ladner H., Kim U.-J., Stetter K.O., Simon M.I., Miller J.H.
    Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827.

Entry informationi

Entry nameiTRPF_PYRAE
AccessioniPrimary (citable) accession number: Q8ZV18
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 25, 2003
Last sequence update: March 1, 2002
Last modified: September 3, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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