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Protein
Submitted name:

Pyruvate dehydrogenase E2 (Dihydrolipoamide acetyltransferase)

Gene

PAE2648

Organism
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseImported
LigandPyruvateImported

Enzyme and pathway databases

BioCyciPAER178306:GCEO-1906-MONOMER

Names & Taxonomyi

Protein namesi
Submitted name:
Pyruvate dehydrogenase E2 (Dihydrolipoamide acetyltransferase)Imported
Gene namesi
Ordered Locus Names:PAE2648Imported
OrganismiPyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)Imported
Taxonomic identifieri178306 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
Proteomesi
  • UP000002439 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi178306.PAE2648

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1W4INMR-A93-152[»]
1W4JNMR-A93-141[»]
1W4KNMR-A93-141[»]
ProteinModelPortaliQ8ZUR6
SMRiQ8ZUR6
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8ZUR6

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 75Lipoyl-bindingInterPro annotationAdd BLAST75
Domaini96 – 133Peripheral subunit-binding (PSBD)InterPro annotationAdd BLAST38

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili272 – 292Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiarCOG01706 Archaea
COG0508 LUCA
HOGENOMiHOG000281564
InParanoidiQ8ZUR6
KOiK00627
OMAiMKVPSPG
OrthoDBiPOG093Z0ML5

Family and domain databases

Gene3Di3.30.559.101 hit
4.10.320.101 hit
InterProiView protein in InterPro
IPR003016 2-oxoA_DH_lipoyl-BS
IPR001078 2-oxoacid_DH_actylTfrase
IPR000089 Biotin_lipoyl
IPR023213 CAT-like_dom_sf
IPR036625 E3-bd_dom_sf
IPR004167 PSBD
IPR011053 Single_hybrid_motif
PfamiView protein in Pfam
PF00198 2-oxoacid_dh, 1 hit
PF00364 Biotin_lipoyl, 1 hit
PF02817 E3_binding, 1 hit
SUPFAMiSSF47005 SSF47005, 1 hit
SSF51230 SSF51230, 1 hit
PROSITEiView protein in PROSITE
PS50968 BIOTINYL_LIPOYL, 1 hit
PS00189 LIPOYL, 1 hit
PS51826 PSBD, 1 hit

Sequencei

Sequence statusi: Complete.

Q8ZUR6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEFKFPDLGE GLVEGEVIKW HVKEGDFVKE GDPLVDVMTE KATVTLPAPT
60 70 80 90 100
TGRVVKILVR EGEVVKVGQT LCVIEPAEGP AAGPQTEAPA RPREVAAMPA
110 120 130 140 150
ARRLAKELGI DLSKVKGTGP GGVITVEDVK RYAEETAKAT APAPAPKAVE
160 170 180 190 200
KAEEAEVVPV RGIRRAVAEK MSKAKRLIPH AYHLEEVDFT ELIKLRERVK
210 220 230 240 250
AEAEKRGIRL TLLPFIAKAV AMALREYPML NSEYDEEKNA IVVKKEVNLG
260 270 280 290 300
IGVDTEQGLV VVVVKNADKK GLLEMAKEIN ELAQKAREGK LELQDVRGST
310 320 330 340 350
FTISNIGAVG GLGGLSILNY PEAGILAVGQ ARKKPWAVGD RIEIRDIALL
360 370 380
AVSFDHRVVD GAYVARFMNR VKELLENPWL LLL
Length:383
Mass (Da):41,689
Last modified:March 1, 2002 - v1
Checksum:i82D446F290120193
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE009441 Genomic DNA Translation: AAL64340.1

Genome annotation databases

EnsemblBacteriaiAAL64340; AAL64340; PAE2648
KEGGipai:PAE2648
PATRICifig|178306.9.peg.1972

Entry informationi

Entry nameiQ8ZUR6_PYRAE
AccessioniPrimary (citable) accession number: Q8ZUR6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: March 28, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported