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Q8ZT64 (CAPPA_PYRAE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase
Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppcA
Ordered Locus Names:PAE3416
OrganismPyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827) [Reference proteome] [HAMAP]
Taxonomic identifier178306 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Thermoproteales › Thermoproteaceae › Pyrobaculum ›

Protein attributes

Sequence length460 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_01904

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_01904

Cofactor

Magnesium By similarity.

Subunit structure

Homotetramer By similarity.

Sequence similarities

Belongs to the PEPCase type 2 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 460460Phosphoenolpyruvate carboxylase HAMAP-Rule MF_01904
PRO_0000309607

Sequences

Sequence LengthMass (Da)Tools
Q8ZT64 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: A2FD72765E7E385C

FASTA46051,486
        10         20         30         40         50         60 
MYIPCLMCTQ HPDSTVKITA GEEVDEAVVA FLAYGCDEVM VDYEGKATPY SQPRDVASKA 

        70         80         90        100        110        120 
LALGLPLGER FFITPRVPNP RLEDFERSML SLEAAVLANS YSQRAAGVQA VKWVVLPMTE 

       130        140        150        160        170        180 
DVETMAFVYK ALDMKARDLA ELNAVKRDSS IELIPLVEDA MRQIKIESFI KALFRTAAQS 

       190        200        210        220        230        240 
GRILEHMRIF LGISDSAVRH GHMASALAMV KALGQISEIN RDGEFKISPI VGMGSPPFRG 

       250        260        270        280        290        300 
GLNNPHLAVP EAAQYAGYKT ATIQSAVRYD VSYAEYQKVR EAILSVYTPR RLHVEEAWIT 

       310        320        330        340        350        360 
KASELYREAI RPYIGKIAEL ANAIPSTRDR VSWREYGRVI EGVEWRVPRA IVYTATWYFA 

       370        380        390        400        410        420 
GVPPTLLDAR FIAWAYKNDL LDDVLRALPA TVEEWKFESR FYSRERAEKT LGGEIVKDID 

       430        440        450        460 
NAFDILGIKP EPDRTYITLL NSADTQPHAI ALGRIRGFLG

« Hide

References

[1]"Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum."
Fitz-Gibbon S.T., Ladner H., Kim U.-J., Stetter K.O., Simon M.I., Miller J.H.
Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE009441 Genomic DNA. Translation: AAL64899.1.
RefSeqNP_560717.1. NC_003364.1.

3D structure databases

ProteinModelPortalQ8ZT64.
ModBaseSearch...

Protein-protein interaction databases

STRING178306.PAE3416.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL64899; AAL64899; PAE3416.
GeneID1464096.
KEGGpai:PAE3416.

Phylogenomic databases

eggNOGCOG1892.
HOGENOMHOG000009826.
KOK01595.
OMAMCTQHPD.
ProtClustDBPRK13655.

Family and domain databases

HAMAPMF_01904. PEPcase_type2.
InterProIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase.
[Graphical view]
PIRSFPIRSF006677. UCP006677. 1 hit.
SUPFAMSSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
TIGRFAMsTIGR02751. PEPCase_arch. 1 hit.
ProtoNetSearch...

Entry information

Entry nameCAPPA_PYRAE
AccessionPrimary (citable) accession number: Q8ZT64
Entry history
Integrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: March 1, 2002
Last modified: May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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