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Q8ZT64

- CAPPA_PYRAE

UniProt

Q8ZT64 - CAPPA_PYRAE

Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Pyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

    Catalytic activityi

    Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

    Cofactori

    Magnesium.UniRule annotation

    GO - Molecular functioni

    1. magnesium ion binding Source: UniProtKB-HAMAP
    2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. carbon fixation Source: UniProtKB-HAMAP
    2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
    3. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Carbon dioxide fixation

    Keywords - Ligandi

    Magnesium

    Enzyme and pathway databases

    BioCyciPAER178306:GCEO-2503-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
    Short name:
    PEPCUniRule annotation
    Short name:
    PEPCaseUniRule annotation
    Gene namesi
    Name:ppcAUniRule annotation
    Ordered Locus Names:PAE3416
    OrganismiPyrobaculum aerophilum (strain ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827)
    Taxonomic identifieri178306 [NCBI]
    Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiThermoprotealesThermoproteaceaePyrobaculum
    ProteomesiUP000002439: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 460460Phosphoenolpyruvate carboxylasePRO_0000309607Add
    BLAST

    Interactioni

    Subunit structurei

    Homotetramer.UniRule annotation

    Protein-protein interaction databases

    STRINGi178306.PAE3416.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8ZT64.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PEPCase type 2 family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1892.
    HOGENOMiHOG000009826.
    KOiK01595.
    OMAiNVPRAIV.

    Family and domain databases

    HAMAPiMF_01904. PEPcase_type2.
    InterProiIPR007566. PEP_COase_arc-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view]
    PfamiPF14010. PEPcase_2. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006677. UCP006677. 1 hit.
    SUPFAMiSSF51621. SSF51621. 1 hit.
    TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q8ZT64-1 [UniParc]FASTAAdd to Basket

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    MYIPCLMCTQ HPDSTVKITA GEEVDEAVVA FLAYGCDEVM VDYEGKATPY    50
    SQPRDVASKA LALGLPLGER FFITPRVPNP RLEDFERSML SLEAAVLANS 100
    YSQRAAGVQA VKWVVLPMTE DVETMAFVYK ALDMKARDLA ELNAVKRDSS 150
    IELIPLVEDA MRQIKIESFI KALFRTAAQS GRILEHMRIF LGISDSAVRH 200
    GHMASALAMV KALGQISEIN RDGEFKISPI VGMGSPPFRG GLNNPHLAVP 250
    EAAQYAGYKT ATIQSAVRYD VSYAEYQKVR EAILSVYTPR RLHVEEAWIT 300
    KASELYREAI RPYIGKIAEL ANAIPSTRDR VSWREYGRVI EGVEWRVPRA 350
    IVYTATWYFA GVPPTLLDAR FIAWAYKNDL LDDVLRALPA TVEEWKFESR 400
    FYSRERAEKT LGGEIVKDID NAFDILGIKP EPDRTYITLL NSADTQPHAI 450
    ALGRIRGFLG 460
    Length:460
    Mass (Da):51,486
    Last modified:March 1, 2002 - v1
    Checksum:iA2FD72765E7E385C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE009441 Genomic DNA. Translation: AAL64899.1.
    RefSeqiNP_560717.1. NC_003364.1.
    WP_011009366.1. NC_003364.1.

    Genome annotation databases

    EnsemblBacteriaiAAL64899; AAL64899; PAE3416.
    GeneIDi1464096.
    KEGGipai:PAE3416.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE009441 Genomic DNA. Translation: AAL64899.1 .
    RefSeqi NP_560717.1. NC_003364.1.
    WP_011009366.1. NC_003364.1.

    3D structure databases

    ProteinModelPortali Q8ZT64.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 178306.PAE3416.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL64899 ; AAL64899 ; PAE3416 .
    GeneIDi 1464096.
    KEGGi pai:PAE3416.

    Phylogenomic databases

    eggNOGi COG1892.
    HOGENOMi HOG000009826.
    KOi K01595.
    OMAi NVPRAIV.

    Enzyme and pathway databases

    BioCyci PAER178306:GCEO-2503-MONOMER.

    Family and domain databases

    HAMAPi MF_01904. PEPcase_type2.
    InterProi IPR007566. PEP_COase_arc-type.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    [Graphical view ]
    Pfami PF14010. PEPcase_2. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006677. UCP006677. 1 hit.
    SUPFAMi SSF51621. SSF51621. 1 hit.
    TIGRFAMsi TIGR02751. PEPCase_arch. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum aerophilum."
      Fitz-Gibbon S.T., Ladner H., Kim U.-J., Stetter K.O., Simon M.I., Miller J.H.
      Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51768 / IM2 / DSM 7523 / JCM 9630 / NBRC 100827.

    Entry informationi

    Entry nameiCAPPA_PYRAE
    AccessioniPrimary (citable) accession number: Q8ZT64
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 13, 2007
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3