Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q8ZRS8

- Q8ZRS8_SALTY

UniProt

Q8ZRS8 - Q8ZRS8_SALTY

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Aconitate hydratase 2

Gene

acnB

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

(2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = (Z)-but-2-ene-1,2,3-tricarboxylate + H2O.UniRule annotation
Citrate = isocitrate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. 2-methylisocitrate dehydratase activity Source: UniProtKB-EC
  2. 4 iron, 4 sulfur cluster binding Source: UniProtKB-KW
  3. aconitate hydratase activity Source: UniProtKB-EC

GO - Biological processi

  1. tricarboxylic acid cycle Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Tricarboxylic acid cycleUniRule annotation

Keywords - Ligandi

4Fe-4SSAAS annotation, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-13618.
SENT99287:GCTI-157-MONOMER.
UniPathwayiUPA00223; UER00718.

Names & Taxonomyi

Protein namesi
Recommended name:
Aconitate hydratase 2UniRule annotation (EC:4.2.1.3UniRule annotation, EC:4.2.1.99UniRule annotation)
Alternative name(s):
2-methylisocitrate dehydrataseUniRule annotation
Gene namesi
Name:acnBImported
Ordered Locus Names:STM0158Imported
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)Imported
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001014: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: InterPro
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ8ZRS8.

Interactioni

Protein-protein interaction databases

STRINGi99287.STM0158.

Structurei

3D structure databases

ProteinModelPortaliQ8ZRS8.
SMRiQ8ZRS8. Positions 1-862.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aconitase/IPM isomerase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000205991.
KOiK01682.
OMAiYVPNKRA.
OrthoDBiEOG6N944W.
PhylomeDBiQ8ZRS8.

Family and domain databases

Gene3Di3.20.19.10. 1 hit.
3.30.499.10. 2 hits.
3.40.1060.10. 1 hit.
InterProiIPR015931. Acnase/IPM_dHydase_lsu_aba_1/3.
IPR015937. Acoase/IPM_deHydtase.
IPR001030. Acoase/IPM_deHydtase_lsu_aba.
IPR015928. Aconitase/3IPM_dehydase_swvl.
IPR015932. Aconitase/IPMdHydase_lsu_aba_2.
IPR018136. Aconitase_4Fe-4S_BS.
IPR004406. Aconitase_B_bac.
IPR015933. Aconitase_B_HEAT-like_bac.
IPR015929. Aconitase_B_N_bac.
[Graphical view]
PANTHERiPTHR11670. PTHR11670. 1 hit.
PfamiPF00330. Aconitase. 2 hits.
PF06434. Aconitase_2_N. 1 hit.
PF11791. Aconitase_B_N. 1 hit.
[Graphical view]
PIRSFiPIRSF036687. AcnB. 1 hit.
SUPFAMiSSF52016. SSF52016. 1 hit.
SSF53732. SSF53732. 1 hit.
SSF74778. SSF74778. 1 hit.
TIGRFAMsiTIGR00117. acnB. 1 hit.
PROSITEiPS00450. ACONITASE_1. 1 hit.
PS01244. ACONITASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8ZRS8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLEEYRKHVA ERAAQGIVPK PLDATQMAAL VELLKTPPVG EEEFLLDLLI
60 70 80 90 100
NRVPPGVDEA AYVKAGFLAA VAKGDTTSPL VSPEKAIELL GTMQGGYNIH
110 120 130 140 150
PLIDALDDAK LAPIAAKALS HTLLMFDNFY DVEEKAKAGN EYAKQVMQSW
160 170 180 190 200
ADAEWFLSRP PLAEKITVTV FKVTGETNTD DLSPAPDAWS RPDIPLHAQA
210 220 230 240 250
MLKNAREGIE PDQPGVVGPI KQIEALQKKG YPLAYVGDVV GTGSSRKSAT
260 270 280 290 300
NSVLWFMGDD IPNVPNKRGG GLCLGGKIAP IFFNTMEDAG ALPIEVDVSN
310 320 330 340 350
LNMGDVIDVY PYKGEVRNHE TGELLATFEL KTDVLIDEVR AGGRIPLIIG
360 370 380 390 400
RGLTTKAREA LGLPHSDVFR QAKDVAESSR GFSLAQKMVG RACGVKGIRP
410 420 430 440 450
GAYCEPKMTS VGSQDTTGPM TRDELKDLAC LGFSADLVMQ SFCHTAAYPK
460 470 480 490 500
PVDVTTHHTL PDFIMNRGGV SLRPGDGVIH SWLNRMLLPD TVGTGGDSHT
510 520 530 540 550
RFPIGISFPA GSGLVAFAAA TGVMPLDMPE SVLVRFKGKM QPGITLRDLV
560 570 580 590 600
HAIPLYAIKQ GLLTVEKKGK KNIFSGRILE IEGLPDLKVE QAFELTDASA
610 620 630 640 650
ERSAAGCTIK LNKEPIVEYL TSNIVLLKWM IAEGYGDRRT LERRIQGMEK
660 670 680 690 700
WLADPQLLEA DADAEYAAVI DIDLADIKEP ILCAPNDPDD ARLLSDVQGE
710 720 730 740 750
KIDEVFIGSC MTNIGHFRAA GKLLDNHKGQ LPTRLWVAPP TRMDAAQLTE
760 770 780 790 800
EGYYSVFGKS GARIEIPGCS LCMGNQARVA DGATVVSTST RNFPNRLGTG
810 820 830 840 850
ANVFLASAEL AAVAALIGKL PTPEEYQTYV AQVDKTAVDT YRYLNFDQLS
860
QYTEKADGVI FQTAV
Length:865
Mass (Da):93,529
Last modified:March 1, 2002 - v1
Checksum:iD287309CB026151D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006468 Genomic DNA. Translation: AAL19122.1.
RefSeqiNP_459163.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL19122; AAL19122; STM0158.
GeneIDi1251676.
KEGGistm:STM0158.
PATRICi32378597. VBISalEnt20916_0168.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006468 Genomic DNA. Translation: AAL19122.1 .
RefSeqi NP_459163.1. NC_003197.1.

3D structure databases

ProteinModelPortali Q8ZRS8.
SMRi Q8ZRS8. Positions 1-862.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 99287.STM0158.

Proteomic databases

PRIDEi Q8ZRS8.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL19122 ; AAL19122 ; STM0158 .
GeneIDi 1251676.
KEGGi stm:STM0158.
PATRICi 32378597. VBISalEnt20916_0168.

Phylogenomic databases

HOGENOMi HOG000205991.
KOi K01682.
OMAi YVPNKRA.
OrthoDBi EOG6N944W.
PhylomeDBi Q8ZRS8.

Enzyme and pathway databases

UniPathwayi UPA00223 ; UER00718 .
BioCyci MetaCyc:MONOMER-13618.
SENT99287:GCTI-157-MONOMER.

Family and domain databases

Gene3Di 3.20.19.10. 1 hit.
3.30.499.10. 2 hits.
3.40.1060.10. 1 hit.
InterProi IPR015931. Acnase/IPM_dHydase_lsu_aba_1/3.
IPR015937. Acoase/IPM_deHydtase.
IPR001030. Acoase/IPM_deHydtase_lsu_aba.
IPR015928. Aconitase/3IPM_dehydase_swvl.
IPR015932. Aconitase/IPMdHydase_lsu_aba_2.
IPR018136. Aconitase_4Fe-4S_BS.
IPR004406. Aconitase_B_bac.
IPR015933. Aconitase_B_HEAT-like_bac.
IPR015929. Aconitase_B_N_bac.
[Graphical view ]
PANTHERi PTHR11670. PTHR11670. 1 hit.
Pfami PF00330. Aconitase. 2 hits.
PF06434. Aconitase_2_N. 1 hit.
PF11791. Aconitase_B_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF036687. AcnB. 1 hit.
SUPFAMi SSF52016. SSF52016. 1 hit.
SSF53732. SSF53732. 1 hit.
SSF74778. SSF74778. 1 hit.
TIGRFAMsi TIGR00117. acnB. 1 hit.
PROSITEi PS00450. ACONITASE_1. 1 hit.
PS01244. ACONITASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LT2 / SGSC1412 / ATCC 700720Imported.

Entry informationi

Entry nameiQ8ZRS8_SALTY
AccessioniPrimary (citable) accession number: Q8ZRS8
Entry historyi
Integrated into UniProtKB/TrEMBL: March 1, 2002
Last sequence update: March 1, 2002
Last modified: November 26, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3