yadF

Functionⁱ

Reversible hydration of carbon dioxide.UniRule annotation

Catalytic activityⁱ

H₂CO₃ = CO₂ + H₂O.UniRule annotation

Sites

Feature key	Position(s)	DescriptionActions	Length
Metal bindingⁱ	42	ZincCombined sources	1
Metal bindingⁱ	44	ZincCombined sources	1
Metal bindingⁱ	98	Zinc; via tele nitrogenCombined sources	1
Metal bindingⁱ	101	ZincCombined sources	1

GO - Molecular functionⁱ

carbonate dehydratase activity Source: UniProtKB-UniRule
zinc ion binding Source: UniProtKB-UniRule

Complete GO annotation...

GO - Biological processⁱ

carbon utilization Source: InterPro

Complete GO annotation...

Keywordsⁱ

Molecular function	LyaseUniRule annotationImported
Ligand	Metal-bindingCombined sources, ZincUniRule annotationCombined sources

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Carbonic anhydraseUniRule annotation (EC:4.2.1.1UniRule annotation) Alternative name(s): Carbonate dehydrataseUniRule annotation
Gene namesⁱ	Name:yadFImported Ordered Locus Names:STM0171Imported
Organismⁱ	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)Imported
Taxonomic identifierⁱ	99287 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Salmonella › Salmonella choleraesuis › Salmonella enterica I › Salmonella typhimurium
Proteomesⁱ	UP000001014 Componentⁱ: Chromosome

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	Q8ZRS0.
PRIDEⁱ	Q8ZRS0.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	99287.STM0171.

STRINGⁱ

99287.STM0171.

Structureⁱ

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	3QY1	X-ray	1.54	A/B	1-220	[»]
ProteinModelPortalⁱ	Q8ZRS0.
SMRⁱ	Q8ZRS0.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	Q8ZRS0.

EvolutionaryTraceⁱ

Q8ZRS0.

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the beta-class carbonic anhydrase family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	ENOG41077A9. Bacteria. COG0288. LUCA.
HOGENOMⁱ	HOG000125184.
KEGG Orthology (KO) More...KOⁱ	K01673.
OMAⁱ	AWERGQD.
PhylomeDBⁱ	Q8ZRS0.

Family and domain databases

Gene3Dⁱ	3.40.1050.10. 1 hit.
InterProⁱ	View protein in InterPro IPR001765. Carbonic_anhydrase. IPR015892. Carbonic_anhydrase_CS.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00484. Pro_CA. 1 hit.
SMARTⁱ	View protein in SMART SM00947. Pro_CA. 1 hit.
SUPFAMⁱ	SSF53056. SSF53056. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00704. PROK_CO2_ANHYDRASE_1. 1 hit. PS00705. PROK_CO2_ANHYDRASE_2. 1 hit.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q8ZRS0-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MKDIDTLISN NALWSKMLVE EDPGFFEKLA QAQKPRFLWI GCSDSRVPAE 
        60         70         80         90        100
RLTGLEPGEL FVHRNVANLV IHTDLNCLSV VQYAVDVLEV EHIIICGHSG 
       110        120        130        140        150
CGGIKAAVEN PELGLINNWL LHIRDIWLKH SSLLGKMPEE QRLDALYELN 
       160        170        180        190        200
VMEQVYNLGH STIMQSAWKR GQNVTIHGWA YSINDGLLRD LDVTATNRET 
       210        220
LENGYHKGIS ALSLKYIPHQ

Length:220

Mass (Da):24,821

Last modified:March 1, 2002 - v1

Checksum:ⁱ66554450930596DD

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AE006468 Genomic DNA. Translation: AAL19135.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_459176.1. NC_003197.2. WP_000651591.1. NC_003197.2.

Genome annotation databases

EnsemblBacteriaⁱ	AAL19135; AAL19135; STM0171.
GeneIDⁱ	1251689.
KEGGⁱ	stm:STM0171.
PATRICⁱ	fig\|99287.12.peg.181.

Similar proteinsⁱ

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q8ZRS0	Q57T84 A0A0F7J628 A0A0R9NBK9 A0A1R3AVI5 A0A0D6HHZ3 A0A0T9WYL2 A0A0M0QDS4 A0A0G2NJZ0 X2KEX3 B5F820 +25	Salmonella choleraesuis (strain SC-B67) Salmonella enterica I Salmonella newport Salmonella enteritidis Salmonella typhimurium Salmonella enterica subsp. enterica serovar Bovismorbificans Salmonella choleraesuis Salmonella enterica subsp. enterica serovar Gallinarum str. SG9 Salmonella enterica subsp. enterica serovar Tennessee str. TXSC_TXSC08-19 Salmonella agona (strain SL483) And more	237	UniRef100_Q57T84	Cluster: Carbonic anhydrase	36

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q8ZRS0	Q8Z9D8 Q57T84 A0A0F7J628 A0A0R9NBK9 A0A1R3AVI5 A0A0D6HHZ3 A0A0T9WYL2 A0A0M0QDS4 A0A0G2NJZ0 X2KEX3 +89	Salmonella typhi Salmonella choleraesuis (strain SC-B67) Salmonella enterica I Salmonella newport Salmonella enteritidis Salmonella typhimurium Salmonella enterica subsp. enterica serovar Bovismorbificans Salmonella choleraesuis Salmonella enterica subsp. enterica serovar Gallinarum str. SG9 Salmonella enterica subsp. enterica serovar Tennessee str. TXSC_TXSC08-19 And more	220	UniRef90_Q8Z9D8	Cluster: Carbonic anhydrase	100

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q8ZRS0	A0A086SLX8 A0A0H3QD61 D7HDT0 A0A0K9UHE7 Q9KUD6 A0A0X1L2X0 C3LS76 A0A0H3AGY6 UPI00069EAFA2 UPI000218FE7D +575	Vibrio cholerae Vibrio cholerae B33 Vibrio cholerae RC385 Vibrio cholerae 2740-80 Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) Vibrio cholerae (strain MO10) Vibrio cholerae serotype O1 (strain M66-2) Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395) Vibrio albensis VL426 Vibrio mimicus VM603 And more	222	UniRef50_A0A086SLX8	Cluster: Carbonic anhydrase	586

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AE006468 Genomic DNA. Translation: AAL19135.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_459176.1. NC_003197.2. WP_000651591.1. NC_003197.2.

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	3QY1	X-ray	1.54	A/B	1-220	[»]
ProteinModelPortalⁱ	Q8ZRS0.
SMRⁱ	Q8ZRS0.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	99287.STM0171.

STRINGⁱ

99287.STM0171.

Proteomic databases

PaxDbⁱ	Q8ZRS0.
PRIDEⁱ	Q8ZRS0.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAL19135; AAL19135; STM0171.
GeneIDⁱ	1251689.
KEGGⁱ	stm:STM0171.
PATRICⁱ	fig\|99287.12.peg.181.

Phylogenomic databases

eggNOGⁱ	ENOG41077A9. Bacteria. COG0288. LUCA.
HOGENOMⁱ	HOG000125184.
KEGG Orthology (KO) More...KOⁱ	K01673.
OMAⁱ	AWERGQD.
PhylomeDBⁱ	Q8ZRS0.

Miscellaneous databases

EvolutionaryTraceⁱ	Q8ZRS0.

EvolutionaryTraceⁱ

Q8ZRS0.

Family and domain databases

Gene3Dⁱ	3.40.1050.10. 1 hit.
InterProⁱ	View protein in InterPro IPR001765. Carbonic_anhydrase. IPR015892. Carbonic_anhydrase_CS.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00484. Pro_CA. 1 hit.
SMARTⁱ	View protein in SMART SM00947. Pro_CA. 1 hit.
SUPFAMⁱ	SSF53056. SSF53056. 1 hit.
PROSITEⁱ	View protein in PROSITE PS00704. PROK_CO2_ANHYDRASE_1. 1 hit. PS00705. PROK_CO2_ANHYDRASE_2. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q8ZRS0_SALTY
Accessionⁱ	Q8ZRS0Primary (citable) accession number: Q8ZRS0
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	March 1, 2002
	Last sequence update:	March 1, 2002
	Last modified:	August 30, 2017
	This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structureCombined sources, Complete proteome, Reference proteomeImported

UniProtKB - Q8ZRS0 (Q8ZRS0_SALTY)

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Carbonic anhydrase

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Functionⁱ

Catalytic activityⁱ

Sites

GO - Molecular functionⁱ

GO - Biological processⁱ

Keywordsⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Proteomic databases

Interactionⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Miscellaneous databases

Family & Domainsⁱ

Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Miscellaneous databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q8ZRS0 (Q8ZRS0_SALTY)

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Carbonic anhydrase

yadF

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ