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Protein

Carbonic anhydrase

Gene

yadF

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

H2CO3 = CO2 + H2O.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi42 – 421ZincCombined sources
Metal bindingi44 – 441ZincCombined sources
Metal bindingi98 – 981Zinc; via tele nitrogenCombined sources
Metal bindingi101 – 1011ZincCombined sources

GO - Molecular functioni

  1. carbonate dehydratase activity Source: UniProtKB-EC
  2. zinc ion binding Source: InterPro

GO - Biological processi

  1. carbon utilization Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationImported

Keywords - Ligandi

Metal-bindingCombined sources, ZincUniRule annotationCombined sources

Enzyme and pathway databases

BioCyciSENT99287:GCTI-170-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Carbonic anhydraseUniRule annotation (EC:4.2.1.1UniRule annotation)
Gene namesi
Name:yadFImported
Ordered Locus Names:STM0171Imported
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)Imported
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001014 Componenti: Chromosome

PTM / Processingi

Proteomic databases

PRIDEiQ8ZRS0.

Interactioni

Protein-protein interaction databases

STRINGi99287.STM0171.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3QY1X-ray1.54A/B1-220[»]
ProteinModelPortaliQ8ZRS0.
SMRiQ8ZRS0. Positions 2-215.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ8ZRS0.

Family & Domainsi

Sequence similaritiesi

Belongs to the beta-class carbonic anhydrase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000125184.
KOiK01673.
OMAiCEINVIE.
OrthoDBiEOG6FFSB8.
PhylomeDBiQ8ZRS0.

Family and domain databases

Gene3Di3.40.1050.10. 1 hit.
InterProiIPR001765. Carbonic_anhydrase.
IPR015892. Carbonic_anhydrase_CS.
[Graphical view]
PANTHERiPTHR11002. PTHR11002. 1 hit.
PfamiPF00484. Pro_CA. 1 hit.
[Graphical view]
SMARTiSM00947. Pro_CA. 1 hit.
[Graphical view]
SUPFAMiSSF53056. SSF53056. 1 hit.
PROSITEiPS00704. PROK_CO2_ANHYDRASE_1. 1 hit.
PS00705. PROK_CO2_ANHYDRASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8ZRS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKDIDTLISN NALWSKMLVE EDPGFFEKLA QAQKPRFLWI GCSDSRVPAE
60 70 80 90 100
RLTGLEPGEL FVHRNVANLV IHTDLNCLSV VQYAVDVLEV EHIIICGHSG
110 120 130 140 150
CGGIKAAVEN PELGLINNWL LHIRDIWLKH SSLLGKMPEE QRLDALYELN
160 170 180 190 200
VMEQVYNLGH STIMQSAWKR GQNVTIHGWA YSINDGLLRD LDVTATNRET
210 220
LENGYHKGIS ALSLKYIPHQ
Length:220
Mass (Da):24,821
Last modified:February 28, 2002 - v1
Checksum:i66554450930596DD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006468 Genomic DNA. Translation: AAL19135.1.
RefSeqiNP_459176.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL19135; AAL19135; STM0171.
GeneIDi1251689.
KEGGistm:STM0171.
PATRICi32378623. VBISalEnt20916_0181.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006468 Genomic DNA. Translation: AAL19135.1.
RefSeqiNP_459176.1. NC_003197.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3QY1X-ray1.54A/B1-220[»]
ProteinModelPortaliQ8ZRS0.
SMRiQ8ZRS0. Positions 2-215.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi99287.STM0171.

Proteomic databases

PRIDEiQ8ZRS0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL19135; AAL19135; STM0171.
GeneIDi1251689.
KEGGistm:STM0171.
PATRICi32378623. VBISalEnt20916_0181.

Phylogenomic databases

HOGENOMiHOG000125184.
KOiK01673.
OMAiCEINVIE.
OrthoDBiEOG6FFSB8.
PhylomeDBiQ8ZRS0.

Enzyme and pathway databases

BioCyciSENT99287:GCTI-170-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ8ZRS0.

Family and domain databases

Gene3Di3.40.1050.10. 1 hit.
InterProiIPR001765. Carbonic_anhydrase.
IPR015892. Carbonic_anhydrase_CS.
[Graphical view]
PANTHERiPTHR11002. PTHR11002. 1 hit.
PfamiPF00484. Pro_CA. 1 hit.
[Graphical view]
SMARTiSM00947. Pro_CA. 1 hit.
[Graphical view]
SUPFAMiSSF53056. SSF53056. 1 hit.
PROSITEiPS00704. PROK_CO2_ANHYDRASE_1. 1 hit.
PS00705. PROK_CO2_ANHYDRASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LT2 / SGSC1412 / ATCC 700720Imported.
  2. "1.54A Resolution Crystal Structure of a Beta-Carbonic Anhydrase from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2."
    Center for Structural Genomics of Infectious Diseases (CSGID)
    Brunzelle J.S., Wawrzak Z., Onopriyenko O., Anderson W.F., Savchenko A.
    Submitted (FEB-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (1.54 ANGSTROMS) IN COMPLEX WITH ZINC.

Entry informationi

Entry nameiQ8ZRS0_SALTY
AccessioniPrimary (citable) accession number: Q8ZRS0
Entry historyi
Integrated into UniProtKB/TrEMBL: February 28, 2002
Last sequence update: February 28, 2002
Last modified: January 6, 2015
This is version 83 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.