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Q8ZRS0

- Q8ZRS0_SALTY

UniProt

Q8ZRS0 - Q8ZRS0_SALTY

Protein

Carbonic anhydrase

Gene

yadF

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    H2CO3 = CO2 + H2O.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi42 – 421ZincImported
    Metal bindingi44 – 441ZincImported
    Metal bindingi98 – 981Zinc; via tele nitrogenImported
    Metal bindingi101 – 1011ZincImported

    GO - Molecular functioni

    1. carbonate dehydratase activity Source: UniProtKB-EC
    2. zinc ion binding Source: InterPro

    GO - Biological processi

    1. carbon utilization Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationImported

    Keywords - Ligandi

    Metal-bindingImported, ZincUniRule annotationImported

    Enzyme and pathway databases

    BioCyciSENT99287:GCTI-170-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Carbonic anhydraseUniRule annotation (EC:4.2.1.1UniRule annotation)
    Gene namesi
    Name:yadFImported
    Ordered Locus Names:STM0171Imported
    OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)Imported
    Taxonomic identifieri99287 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
    ProteomesiUP000001014: Chromosome

    PTM / Processingi

    Proteomic databases

    PRIDEiQ8ZRS0.

    Interactioni

    Protein-protein interaction databases

    STRINGi99287.STM0171.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3QY1X-ray1.54A/B1-220[»]
    ProteinModelPortaliQ8ZRS0.
    SMRiQ8ZRS0. Positions 2-215.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ8ZRS0.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the beta-class carbonic anhydrase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000125184.
    KOiK01673.
    OMAiCEINVIE.
    OrthoDBiEOG6FFSB8.
    PhylomeDBiQ8ZRS0.

    Family and domain databases

    Gene3Di3.40.1050.10. 1 hit.
    InterProiIPR001765. Carbonic_anhydrase.
    IPR015892. Carbonic_anhydrase_CS.
    [Graphical view]
    PANTHERiPTHR11002. PTHR11002. 1 hit.
    PfamiPF00484. Pro_CA. 1 hit.
    [Graphical view]
    SMARTiSM00947. Pro_CA. 1 hit.
    [Graphical view]
    SUPFAMiSSF53056. SSF53056. 1 hit.
    PROSITEiPS00704. PROK_CO2_ANHYDRASE_1. 1 hit.
    PS00705. PROK_CO2_ANHYDRASE_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8ZRS0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKDIDTLISN NALWSKMLVE EDPGFFEKLA QAQKPRFLWI GCSDSRVPAE    50
    RLTGLEPGEL FVHRNVANLV IHTDLNCLSV VQYAVDVLEV EHIIICGHSG 100
    CGGIKAAVEN PELGLINNWL LHIRDIWLKH SSLLGKMPEE QRLDALYELN 150
    VMEQVYNLGH STIMQSAWKR GQNVTIHGWA YSINDGLLRD LDVTATNRET 200
    LENGYHKGIS ALSLKYIPHQ 220
    Length:220
    Mass (Da):24,821
    Last modified:March 1, 2002 - v1
    Checksum:i66554450930596DD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006468 Genomic DNA. Translation: AAL19135.1.
    RefSeqiNP_459176.1. NC_003197.1.

    Genome annotation databases

    EnsemblBacteriaiAAL19135; AAL19135; STM0171.
    GeneIDi1251689.
    KEGGistm:STM0171.
    PATRICi32378623. VBISalEnt20916_0181.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006468 Genomic DNA. Translation: AAL19135.1 .
    RefSeqi NP_459176.1. NC_003197.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3QY1 X-ray 1.54 A/B 1-220 [» ]
    ProteinModelPortali Q8ZRS0.
    SMRi Q8ZRS0. Positions 2-215.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 99287.STM0171.

    Proteomic databases

    PRIDEi Q8ZRS0.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL19135 ; AAL19135 ; STM0171 .
    GeneIDi 1251689.
    KEGGi stm:STM0171.
    PATRICi 32378623. VBISalEnt20916_0181.

    Phylogenomic databases

    HOGENOMi HOG000125184.
    KOi K01673.
    OMAi CEINVIE.
    OrthoDBi EOG6FFSB8.
    PhylomeDBi Q8ZRS0.

    Enzyme and pathway databases

    BioCyci SENT99287:GCTI-170-MONOMER.

    Miscellaneous databases

    EvolutionaryTracei Q8ZRS0.

    Family and domain databases

    Gene3Di 3.40.1050.10. 1 hit.
    InterProi IPR001765. Carbonic_anhydrase.
    IPR015892. Carbonic_anhydrase_CS.
    [Graphical view ]
    PANTHERi PTHR11002. PTHR11002. 1 hit.
    Pfami PF00484. Pro_CA. 1 hit.
    [Graphical view ]
    SMARTi SM00947. Pro_CA. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53056. SSF53056. 1 hit.
    PROSITEi PS00704. PROK_CO2_ANHYDRASE_1. 1 hit.
    PS00705. PROK_CO2_ANHYDRASE_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LT2 / SGSC1412 / ATCC 700720Imported.
    2. "1.54A Resolution Crystal Structure of a Beta-Carbonic Anhydrase from Salmonella enterica subsp. enterica serovar Typhimurium str. LT2."
      Center for Structural Genomics of Infectious Diseases (CSGID)
      Brunzelle J.S., Wawrzak Z., Onopriyenko O., Anderson W.F., Savchenko A.
      Submitted (MAR-2011) to the PDB data bank
      Cited for: X-RAY CRYSTALLOGRAPHY (1.54 ANGSTROMS) IN COMPLEX WITH ZINC.

    Entry informationi

    Entry nameiQ8ZRS0_SALTY
    AccessioniPrimary (citable) accession number: Q8ZRS0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 1, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3