yadF

Functionⁱ

Reversible hydration of carbon dioxide.UniRule annotation

Catalytic activityⁱ

H₂CO₃ = CO₂ + H₂O.UniRule annotation

Sites

Feature key	Position(s)	DescriptionActions	Length
Metal bindingⁱ	42	ZincCombined sources	1
Metal bindingⁱ	44	ZincCombined sources	1
Metal bindingⁱ	98	Zinc; via tele nitrogenCombined sources	1
Metal bindingⁱ	101	ZincCombined sources	1

GO - Molecular functionⁱ

carbonate dehydratase activity Source: UniProtKB-UniRule
zinc ion binding Source: UniProtKB-UniRule

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

carbon utilization Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	LyaseUniRule annotationImported
Ligand	Metal-bindingCombined sources, ZincUniRule annotationCombined sources

Enzyme and pathway databases

BioCycⁱ	SENT99287:G1FZD-173-MONOMER

BioCycⁱ

SENT99287:G1FZD-173-MONOMER

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Carbonic anhydraseUniRule annotation (EC:4.2.1.1UniRule annotation) Alternative name(s): Carbonate dehydrataseUniRule annotation
Gene namesⁱ	Name:yadFImported Ordered Locus Names:STM0171Imported
Organismⁱ	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)Imported
Taxonomic identifierⁱ	99287 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Enterobacteriaceae › Salmonella › Salmonella choleraesuis › Salmonella enterica I › Salmonella typhimurium
Proteomesⁱ	UP000001014 Componentⁱ: Chromosome

PTM / Processingⁱ

Proteomic databases

PaxDbⁱ	Q8ZRS0
PRIDEⁱ	Q8ZRS0

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	99287.STM0171

STRINGⁱ

99287.STM0171

Structureⁱ

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	3QY1	X-ray	1.54	A/B	1-220	[»]
ProteinModelPortalⁱ	Q8ZRS0
SMRⁱ	Q8ZRS0
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	Q8ZRS0

EvolutionaryTraceⁱ

Q8ZRS0

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the beta-class carbonic anhydrase family.UniRule annotation

Phylogenomic databases

eggNOGⁱ	ENOG41077A9 Bacteria COG0288 LUCA
HOGENOMⁱ	HOG000125184
KEGG Orthology (KO) More...KOⁱ	K01673
OMAⁱ	AWERGQD
PhylomeDBⁱ	Q8ZRS0

Family and domain databases

Gene3Dⁱ	3.40.1050.101 hit
InterProⁱ	View protein in InterPro IPR001765 Carbonic_anhydrase IPR015892 Carbonic_anhydrase_CS IPR036874 Carbonic_anhydrase_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00484 Pro_CA, 1 hit
SMARTⁱ	View protein in SMART SM00947 Pro_CA, 1 hit
SUPFAMⁱ	SSF53056 SSF53056, 1 hit
PROSITEⁱ	View protein in PROSITE PS00704 PROK_CO2_ANHYDRASE_1, 1 hit PS00705 PROK_CO2_ANHYDRASE_2, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q8ZRS0-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MKDIDTLISN NALWSKMLVE EDPGFFEKLA QAQKPRFLWI GCSDSRVPAE 
        60         70         80         90        100
RLTGLEPGEL FVHRNVANLV IHTDLNCLSV VQYAVDVLEV EHIIICGHSG 
       110        120        130        140        150
CGGIKAAVEN PELGLINNWL LHIRDIWLKH SSLLGKMPEE QRLDALYELN 
       160        170        180        190        200
VMEQVYNLGH STIMQSAWKR GQNVTIHGWA YSINDGLLRD LDVTATNRET 
       210        220
LENGYHKGIS ALSLKYIPHQ

Length:220

Mass (Da):24,821

Last modified:March 1, 2002 - v1

Checksum:ⁱ66554450930596DD

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AE006468 Genomic DNA Translation: AAL19135.1
NCBI Reference Sequences More...RefSeqⁱ	NP_459176.1, NC_003197.2 WP_000651591.1, NC_003197.2

Genome annotation databases

EnsemblBacteriaⁱ	AAL19135; AAL19135; STM0171
GeneIDⁱ	1251689
KEGGⁱ	stm:STM0171
PATRICⁱ	fig\|99287.12.peg.181

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q8ZRS0	Q57T84 UPI00073C2FA9 A0A2L1EW44 A0A0F7J628 A0A0R9NBK9 A0A0D6HHZ3 A0A0M0QDS4 A0A1R3AVI5 A0A0T9WYL2 S4I3T7 +26	Salmonella choleraesuis (strain SC-B67) Salmonella choleraesuis Salmonella derby Salmonella enterica I Salmonella newport Salmonella typhimurium Salmonella enteritidis Salmonella enterica subsp. enterica serovar Bovismorbificans Salmonella enterica subsp. enterica serovar Enteritidis str. 2009K0958 Salmonella enterica subsp. enterica serovar Tennessee And more	237	UniRef100_Q57T84	Cluster: Carbonic anhydrase	37

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q8ZRS0	D2THE3 Q57T84 UPI00073C2FA9 A0A2L1EW44 A0A0F7J628 A0A0R9NBK9 A0A0D6HHZ3 A0A0M0QDS4 A0A1R3AVI5 A0A0T9WYL2 +99	Citrobacter rodentium (strain ICC168) (Citrobacter freundii biotype 4280) Salmonella choleraesuis (strain SC-B67) Salmonella choleraesuis Salmonella derby Salmonella enterica I Salmonella newport Salmonella typhimurium Salmonella enteritidis Salmonella enterica subsp. enterica serovar Bovismorbificans Salmonella enterica subsp. enterica serovar Enteritidis str. 2009K0958 And more	220	UniRef90_D2THE3	Cluster: Carbonic anhydrase	110

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q8ZRS0	A0A191W1L0 F7YPI0 A0A233I9L2 A0A1E5FEX6 A0A233HL29 UPI00030EF48E A0A0L7YTM2 A0A289G9Q0 A0A223MVH0 UPI0002F1D577 +612	Vibrio anguillarum (Listonella anguillarum) Vibrio anguillarum (strain ATCC 68554 / 775) (Listonella anguillarum) Vibrio sp. V03_P4A6T147 Vibrio ordalii 12B09 Vibrio sp. V15_P4S5T153 Vibrio ordalii Vibrio alginolyticus Vibrio qinghaiensis Vibrio litoralis Vibrio rumoiensis 1S-45 And more	222	UniRef50_A0A191W1L0	Cluster: Carbonic anhydrase	623

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AE006468 Genomic DNA Translation: AAL19135.1
NCBI Reference Sequences More...RefSeqⁱ	NP_459176.1, NC_003197.2 WP_000651591.1, NC_003197.2

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	3QY1	X-ray	1.54	A/B	1-220	[»]
ProteinModelPortalⁱ	Q8ZRS0
SMRⁱ	Q8ZRS0
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	99287.STM0171

STRINGⁱ

99287.STM0171

Proteomic databases

PaxDbⁱ	Q8ZRS0
PRIDEⁱ	Q8ZRS0

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	AAL19135; AAL19135; STM0171
GeneIDⁱ	1251689
KEGGⁱ	stm:STM0171
PATRICⁱ	fig\|99287.12.peg.181

Phylogenomic databases

eggNOGⁱ	ENOG41077A9 Bacteria COG0288 LUCA
HOGENOMⁱ	HOG000125184
KEGG Orthology (KO) More...KOⁱ	K01673
OMAⁱ	AWERGQD
PhylomeDBⁱ	Q8ZRS0

Enzyme and pathway databases

BioCycⁱ	SENT99287:G1FZD-173-MONOMER

BioCycⁱ

SENT99287:G1FZD-173-MONOMER

Miscellaneous databases

EvolutionaryTraceⁱ	Q8ZRS0

EvolutionaryTraceⁱ

Q8ZRS0

Family and domain databases

Gene3Dⁱ	3.40.1050.101 hit
InterProⁱ	View protein in InterPro IPR001765 Carbonic_anhydrase IPR015892 Carbonic_anhydrase_CS IPR036874 Carbonic_anhydrase_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00484 Pro_CA, 1 hit
SMARTⁱ	View protein in SMART SM00947 Pro_CA, 1 hit
SUPFAMⁱ	SSF53056 SSF53056, 1 hit
PROSITEⁱ	View protein in PROSITE PS00704 PROK_CO2_ANHYDRASE_1, 1 hit PS00705 PROK_CO2_ANHYDRASE_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q8ZRS0_SALTY
Accessionⁱ	Q8ZRS0Primary (citable) accession number: Q8ZRS0
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	March 1, 2002
	Last sequence update:	March 1, 2002
	Last modified:	February 28, 2018
	This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structureCombined sources, Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q8ZRS0 (Q8ZRS0_SALTY)

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Carbonic anhydrase

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

PTM / Processingⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ