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Protein

LPS-assembly lipoprotein LptE

Gene

lptE

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.UniRule annotation

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciSENT99287:GCTI-650-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
LPS-assembly lipoprotein LptEUniRule annotation
Gene namesi
Name:lptEUniRule annotation
Synonyms:rlpB
Ordered Locus Names:STM0647
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

  • Cell outer membrane UniRule annotation; Lipid-anchor UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1818UniRule annotationAdd
BLAST
Chaini19 – 196178LPS-assembly lipoprotein LptEPRO_0000281184Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi19 – 191N-palmitoyl cysteineUniRule annotation
Lipidationi19 – 191S-diacylglycerol cysteineUniRule annotation

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiQ8ZQZ7.
PRIDEiQ8ZQZ7.

Interactioni

Subunit structurei

Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.UniRule annotation

Protein-protein interaction databases

DIPiDIP-61033N.
STRINGi99287.STM0647.

Structurei

Secondary structure

1
196
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi31 – 333Combined sources
Beta strandi34 – 396Combined sources
Helixi46 – 5712Combined sources
Beta strandi61 – 633Combined sources
Beta strandi74 – 8916Combined sources
Beta strandi95 – 10915Combined sources
Beta strandi115 – 12713Combined sources
Helixi130 – 1323Combined sources
Helixi133 – 15725Combined sources
Helixi159 – 1679Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4N4RX-ray2.80B/D1-196[»]
ProteinModelPortaliQ8ZQZ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LptE lipoprotein family.UniRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4108U2H. Bacteria.
COG2980. LUCA.
HOGENOMiHOG000256192.
KOiK03643.
OMAiRKLLTVH.
OrthoDBiEOG67DPND.
PhylomeDBiQ8ZQZ7.

Family and domain databases

HAMAPiMF_01186. LPS_assembly_LptE.
InterProiIPR007485. LPS_assembly_LptE.
[Graphical view]
PfamiPF04390. LptE. 1 hit.
[Graphical view]
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8ZQZ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRYLVTLLLS LAVLVTAGCG WHLRSTTQVP ASMKTMILDS GDPNGPLSRA
60 70 80 90 100
VRNQLRLNNV NLLDKDTTRK DVPSLRLGTV TILQDTASVF QDGQTAEYQM
110 120 130 140 150
VMTVNASVLI PGHDIYPIST KVYRSFFDNP QMALAKDNEQ AMIVQEMYDK
160 170 180 190
AAEQLIRKLT SVRAADIQAT KEEATADNET AAPASTPARV STTLSN
Length:196
Mass (Da):21,458
Last modified:March 1, 2002 - v1
Checksum:i0277352CF72BF8E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006468 Genomic DNA. Translation: AAL19598.1.
RefSeqiNP_459639.1. NC_003197.1.
WP_001269947.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL19598; AAL19598; STM0647.
GeneIDi1252167.
KEGGistm:STM0647.
PATRICi32379647. VBISalEnt20916_0683.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006468 Genomic DNA. Translation: AAL19598.1.
RefSeqiNP_459639.1. NC_003197.1.
WP_001269947.1. NC_003197.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
4N4RX-ray2.80B/D1-196[»]
ProteinModelPortaliQ8ZQZ7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-61033N.
STRINGi99287.STM0647.

Proteomic databases

PaxDbiQ8ZQZ7.
PRIDEiQ8ZQZ7.

Protocols and materials databases

DNASUi1252167.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL19598; AAL19598; STM0647.
GeneIDi1252167.
KEGGistm:STM0647.
PATRICi32379647. VBISalEnt20916_0683.

Phylogenomic databases

eggNOGiENOG4108U2H. Bacteria.
COG2980. LUCA.
HOGENOMiHOG000256192.
KOiK03643.
OMAiRKLLTVH.
OrthoDBiEOG67DPND.
PhylomeDBiQ8ZQZ7.

Enzyme and pathway databases

BioCyciSENT99287:GCTI-650-MONOMER.

Family and domain databases

HAMAPiMF_01186. LPS_assembly_LptE.
InterProiIPR007485. LPS_assembly_LptE.
[Graphical view]
PfamiPF04390. LptE. 1 hit.
[Graphical view]
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LT2 / SGSC1412 / ATCC 700720.

Entry informationi

Entry nameiLPTE_SALTY
AccessioniPrimary (citable) accession number: Q8ZQZ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: March 1, 2002
Last modified: November 11, 2015
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.