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Protein

LPS-assembly lipoprotein LptE

Gene

lptE

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane.UniRule annotation

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
LPS-assembly lipoprotein LptEUniRule annotation
Gene namesi
Name:lptEUniRule annotation
Synonyms:rlpB
Ordered Locus Names:STM0647
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeSalmonella
Proteomesi
  • UP000001014 Componenti: Chromosome

Subcellular locationi

  • Cell outer membrane UniRule annotation; Lipid-anchor UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell outer membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18UniRule annotationAdd BLAST18
ChainiPRO_000028118419 – 196LPS-assembly lipoprotein LptEAdd BLAST178

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi19N-palmitoyl cysteineUniRule annotation1
Lipidationi19S-diacylglycerol cysteineUniRule annotation1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiQ8ZQZ7.
PRIDEiQ8ZQZ7.

Interactioni

Subunit structurei

Component of the lipopolysaccharide transport and assembly complex. Interacts with LptD.UniRule annotation

Protein-protein interaction databases

DIPiDIP-61033N.
STRINGi99287.STM0647.

Structurei

Secondary structure

1196
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi31 – 33Combined sources3
Beta strandi34 – 39Combined sources6
Helixi46 – 57Combined sources12
Beta strandi61 – 63Combined sources3
Beta strandi74 – 89Combined sources16
Beta strandi95 – 109Combined sources15
Beta strandi115 – 127Combined sources13
Helixi130 – 132Combined sources3
Helixi133 – 157Combined sources25
Helixi159 – 167Combined sources9

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4N4RX-ray2.80B/D1-196[»]
ProteinModelPortaliQ8ZQZ7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LptE lipoprotein family.UniRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4108U2H. Bacteria.
COG2980. LUCA.
HOGENOMiHOG000256192.
KOiK03643.
OMAiRKLLTVH.
PhylomeDBiQ8ZQZ7.

Family and domain databases

HAMAPiMF_01186. LPS_assembly_LptE. 1 hit.
InterProiIPR007485. LPS_assembly_LptE.
[Graphical view]
PfamiPF04390. LptE. 1 hit.
[Graphical view]
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q8ZQZ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRYLVTLLLS LAVLVTAGCG WHLRSTTQVP ASMKTMILDS GDPNGPLSRA
60 70 80 90 100
VRNQLRLNNV NLLDKDTTRK DVPSLRLGTV TILQDTASVF QDGQTAEYQM
110 120 130 140 150
VMTVNASVLI PGHDIYPIST KVYRSFFDNP QMALAKDNEQ AMIVQEMYDK
160 170 180 190
AAEQLIRKLT SVRAADIQAT KEEATADNET AAPASTPARV STTLSN
Length:196
Mass (Da):21,458
Last modified:March 1, 2002 - v1
Checksum:i0277352CF72BF8E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006468 Genomic DNA. Translation: AAL19598.1.
RefSeqiNP_459639.1. NC_003197.1.
WP_001269947.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL19598; AAL19598; STM0647.
GeneIDi1252167.
KEGGistm:STM0647.
PATRICi32379647. VBISalEnt20916_0683.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006468 Genomic DNA. Translation: AAL19598.1.
RefSeqiNP_459639.1. NC_003197.1.
WP_001269947.1. NC_003197.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4N4RX-ray2.80B/D1-196[»]
ProteinModelPortaliQ8ZQZ7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-61033N.
STRINGi99287.STM0647.

Proteomic databases

PaxDbiQ8ZQZ7.
PRIDEiQ8ZQZ7.

Protocols and materials databases

DNASUi1252167.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAL19598; AAL19598; STM0647.
GeneIDi1252167.
KEGGistm:STM0647.
PATRICi32379647. VBISalEnt20916_0683.

Phylogenomic databases

eggNOGiENOG4108U2H. Bacteria.
COG2980. LUCA.
HOGENOMiHOG000256192.
KOiK03643.
OMAiRKLLTVH.
PhylomeDBiQ8ZQZ7.

Family and domain databases

HAMAPiMF_01186. LPS_assembly_LptE. 1 hit.
InterProiIPR007485. LPS_assembly_LptE.
[Graphical view]
PfamiPF04390. LptE. 1 hit.
[Graphical view]
PROSITEiPS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLPTE_SALTY
AccessioniPrimary (citable) accession number: Q8ZQZ7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: March 1, 2002
Last modified: November 2, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.