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Q8ZQR4

- 6PGL_SALTY

UniProt

Q8ZQR4 - 6PGL_SALTY

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Protein

6-phosphogluconolactonase

Gene
pgl, STM0785
Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate By similarity.UniRule annotation

Catalytic activityi

6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. 6-phosphogluconolactonase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. pentose-phosphate shunt Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Glucose metabolism

Enzyme and pathway databases

BioCyciSENT99287:GCTI-790-MONOMER.
UniPathwayiUPA00115; UER00409.

Names & Taxonomyi

Protein namesi
Recommended name:
6-phosphogluconolactonase (EC:3.1.1.31)
Short name:
6-P-gluconolactonase
Gene namesi
Name:pgl
Ordered Locus Names:STM0785
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001014: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 3313316-phosphogluconolactonaseUniRule annotationPRO_0000171139Add
BLAST

Proteomic databases

PaxDbiQ8ZQR4.
PRIDEiQ8ZQR4.

Interactioni

Protein-protein interaction databases

STRINGi99287.STM0785.

Structurei

3D structure databases

ProteinModelPortaliQ8ZQR4.
SMRiQ8ZQR4. Positions 1-331.

Family & Domainsi

Sequence similaritiesi

Belongs to the cycloisomerase 2 family.

Phylogenomic databases

eggNOGiCOG2706.
HOGENOMiHOG000257418.
KOiK07404.
OMAiDKRFLYV.
OrthoDBiEOG615VK7.
PhylomeDBiQ8ZQR4.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
HAMAPiMF_01605. 6P_gluconolactonase.
InterProiIPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR011045. N2O_reductase_N.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view]
PfamiPF10282. Lactonase. 1 hit.
[Graphical view]
SUPFAMiSSF50974. SSF50974. 2 hits.

Sequencei

Sequence statusi: Complete.

Q8ZQR4-1 [UniParc]FASTAAdd to Basket

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MKQTVYTASP ESQQIHVWSL NHEGTLTLVQ VVDVPGQVQP MVVSPDKRYL    50
YVGVRPEFRV LAYRIAPDDG ALTFAAESAL PGSPTHISTD HHGRFVFVGS 100
YNAGNVSVTR LQDGLPVELV DVVEGLDGCH SANITPDNRT LWVPALKQDR 150
ICLFTLSDDG HLVAQEPAEV NTVEGAGPRH MVFHPNRQYA YCVNELNSSV 200
DVWQLKNPHG EIECVQTLDM MPADFSDTRW AADIHITPDG RHLYACDRTA 250
SLITVFSVSE DGSVLSVEGF QPTEAQPRGF NIDNSGKYLI AAGQKSHHIA 300
VYEITGTQGL LTEKGRYAVG QGPMWVVVNA Y 331
Length:331
Mass (Da):36,337
Last modified:March 1, 2002 - v1
Checksum:i240B46DF97002DD5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006468 Genomic DNA. Translation: AAL19723.1.
RefSeqiNP_459764.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL19723; AAL19723; STM0785.
GeneIDi1252305.
KEGGistm:STM0785.
PATRICi32379940. VBISalEnt20916_0818.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE006468 Genomic DNA. Translation: AAL19723.1 .
RefSeqi NP_459764.1. NC_003197.1.

3D structure databases

ProteinModelPortali Q8ZQR4.
SMRi Q8ZQR4. Positions 1-331.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 99287.STM0785.

Proteomic databases

PaxDbi Q8ZQR4.
PRIDEi Q8ZQR4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL19723 ; AAL19723 ; STM0785 .
GeneIDi 1252305.
KEGGi stm:STM0785.
PATRICi 32379940. VBISalEnt20916_0818.

Phylogenomic databases

eggNOGi COG2706.
HOGENOMi HOG000257418.
KOi K07404.
OMAi DKRFLYV.
OrthoDBi EOG615VK7.
PhylomeDBi Q8ZQR4.

Enzyme and pathway databases

UniPathwayi UPA00115 ; UER00409 .
BioCyci SENT99287:GCTI-790-MONOMER.

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
HAMAPi MF_01605. 6P_gluconolactonase.
InterProi IPR022528. 6-phosphogluconolactonase_YbhE.
IPR019405. Lactonase_7-beta_prop.
IPR011045. N2O_reductase_N.
IPR015943. WD40/YVTN_repeat-like_dom.
[Graphical view ]
Pfami PF10282. Lactonase. 1 hit.
[Graphical view ]
SUPFAMi SSF50974. SSF50974. 2 hits.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LT2 / SGSC1412 / ATCC 700720.

Entry informationi

Entry namei6PGL_SALTY
AccessioniPrimary (citable) accession number: Q8ZQR4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: March 1, 2002
Last modified: July 9, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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