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Q8ZPZ1 (RLUE_SALTY) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ribosomal large subunit pseudouridine synthase E

EC=5.4.99.20
Alternative name(s):
rRNA pseudouridylate synthase E
rRNA-uridine isomerase E
Gene names
Name:rluE
Ordered Locus Names:STM1237
OrganismSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) [Reference proteome] [HAMAP]
Taxonomic identifier99287 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

Protein attributes

Sequence length221 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA By similarity.

Catalytic activity

23S rRNA uridine(2457) = 23S rRNA pseudouridine(2457).

Sequence similarities

Belongs to the pseudouridine synthase RsuA family.

Ontologies

Keywords
   Biological processrRNA processing
   Molecular functionIsomerase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processpseudouridine synthesis

Inferred from electronic annotation. Source: InterPro

rRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: InterPro

pseudouridine synthase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 221221Ribosomal large subunit pseudouridine synthase E
PRO_0000100008

Sites

Active site791Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8ZPZ1 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 41C5F9A2FFFE6F56

FASTA22125,330
        10         20         30         40         50         60 
MRQLISSENT MQKTSFRNHY VKRFSSRQAS KSRKENQPKR VVLFNKPYDV LPQFTDEAGR 

        70         80         90        100        110        120 
RTLKDFIPVQ GVYAAGRLDR DSEGLLVLTN DGALQARLTQ PGKRTGKIYY VQVEGIPDNA 

       130        140        150        160        170        180 
ALQALRTGVT LNDGPTLPAG IEIVAEPDWL WPRTPPIRER KNIPTSWLKV TLYEGRNRQV 

       190        200        210        220 
RRMTAHVGHP TLRLIRYSMG DYTLNGLDNG QWREIAQEKD R 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE006468 Genomic DNA. Translation: AAL20166.1.
RefSeqNP_460207.1. NC_003197.1.

3D structure databases

ProteinModelPortalQ8ZPZ1.
SMRQ8ZPZ1. Positions 36-215.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING99287.STM1237.

Proteomic databases

PaxDbQ8ZPZ1.
PRIDEQ8ZPZ1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL20166; AAL20166; STM1237.
GeneID1252755.
KEGGstm:STM1237.
PATRIC32380927. VBISalEnt20916_1308.

Phylogenomic databases

eggNOGCOG1187.
HOGENOMHOG000044955.
KOK06181.
OMAYWVQVER.
OrthoDBEOG6130DV.
ProtClustDBCLSK894081.

Enzyme and pathway databases

BioCycSENT99287:GCTI-1246-MONOMER.

Family and domain databases

InterProIPR020103. PsdUridine_synth_cat_dom.
IPR000748. PsdUridine_synth_RsuA/RluB/E/F.
IPR018496. PsdUridine_synth_RsuA/RluB_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
[Graphical view]
PfamPF00849. PseudoU_synth_2. 1 hit.
[Graphical view]
SUPFAMSSF55120. SSF55120. 1 hit.
TIGRFAMsTIGR00093. TIGR00093. 1 hit.
PROSITEPS01149. PSI_RSU. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRLUE_SALTY
AccessionPrimary (citable) accession number: Q8ZPZ1
Entry history
Integrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: March 1, 2002
Last modified: November 13, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families