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Q8ZPZ1

- RLUE_SALTY

UniProt

Q8ZPZ1 - RLUE_SALTY

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Protein

Ribosomal large subunit pseudouridine synthase E

Gene

rluE

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA.By similarity

Catalytic activityi

23S rRNA uridine(2457) = 23S rRNA pseudouridine(2457).

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei79 – 791NucleophileBy similarity

GO - Molecular functioni

  1. pseudouridine synthase activity Source: InterPro
  2. RNA binding Source: InterPro

GO - Biological processi

  1. pseudouridine synthesis Source: InterPro
  2. rRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

rRNA processing

Enzyme and pathway databases

BioCyciSENT99287:GCTI-1246-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal large subunit pseudouridine synthase E (EC:5.4.99.20)
Alternative name(s):
rRNA pseudouridylate synthase E
rRNA-uridine isomerase E
Gene namesi
Name:rluE
Ordered Locus Names:STM1237
OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Taxonomic identifieri99287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
ProteomesiUP000001014: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 221221Ribosomal large subunit pseudouridine synthase EPRO_0000100008Add
BLAST

Proteomic databases

PaxDbiQ8ZPZ1.
PRIDEiQ8ZPZ1.

Interactioni

Protein-protein interaction databases

STRINGi99287.STM1237.

Structurei

3D structure databases

ProteinModelPortaliQ8ZPZ1.
SMRiQ8ZPZ1. Positions 36-215.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase RsuA family.Curated

Phylogenomic databases

eggNOGiCOG1187.
HOGENOMiHOG000044955.
KOiK06181.
OMAiLFNKPFQ.
OrthoDBiEOG6130DV.
PhylomeDBiQ8ZPZ1.

Family and domain databases

InterProiIPR020103. PsdUridine_synth_cat_dom.
IPR000748. PsdUridine_synth_RsuA/RluB/E/F.
IPR018496. PsdUridine_synth_RsuA/RluB_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
[Graphical view]
PfamiPF00849. PseudoU_synth_2. 1 hit.
[Graphical view]
SUPFAMiSSF55120. SSF55120. 1 hit.
TIGRFAMsiTIGR00093. TIGR00093. 1 hit.
PROSITEiPS01149. PSI_RSU. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8ZPZ1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRQLISSENT MQKTSFRNHY VKRFSSRQAS KSRKENQPKR VVLFNKPYDV
60 70 80 90 100
LPQFTDEAGR RTLKDFIPVQ GVYAAGRLDR DSEGLLVLTN DGALQARLTQ
110 120 130 140 150
PGKRTGKIYY VQVEGIPDNA ALQALRTGVT LNDGPTLPAG IEIVAEPDWL
160 170 180 190 200
WPRTPPIRER KNIPTSWLKV TLYEGRNRQV RRMTAHVGHP TLRLIRYSMG
210 220
DYTLNGLDNG QWREIAQEKD R
Length:221
Mass (Da):25,330
Last modified:March 1, 2002 - v1
Checksum:i41C5F9A2FFFE6F56
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006468 Genomic DNA. Translation: AAL20166.1.
RefSeqiNP_460207.1. NC_003197.1.

Genome annotation databases

EnsemblBacteriaiAAL20166; AAL20166; STM1237.
GeneIDi1252755.
KEGGistm:STM1237.
PATRICi32380927. VBISalEnt20916_1308.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE006468 Genomic DNA. Translation: AAL20166.1 .
RefSeqi NP_460207.1. NC_003197.1.

3D structure databases

ProteinModelPortali Q8ZPZ1.
SMRi Q8ZPZ1. Positions 36-215.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 99287.STM1237.

Proteomic databases

PaxDbi Q8ZPZ1.
PRIDEi Q8ZPZ1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAL20166 ; AAL20166 ; STM1237 .
GeneIDi 1252755.
KEGGi stm:STM1237.
PATRICi 32380927. VBISalEnt20916_1308.

Phylogenomic databases

eggNOGi COG1187.
HOGENOMi HOG000044955.
KOi K06181.
OMAi LFNKPFQ.
OrthoDBi EOG6130DV.
PhylomeDBi Q8ZPZ1.

Enzyme and pathway databases

BioCyci SENT99287:GCTI-1246-MONOMER.

Family and domain databases

InterProi IPR020103. PsdUridine_synth_cat_dom.
IPR000748. PsdUridine_synth_RsuA/RluB/E/F.
IPR018496. PsdUridine_synth_RsuA/RluB_CS.
IPR006145. PsdUridine_synth_RsuA/RluD.
[Graphical view ]
Pfami PF00849. PseudoU_synth_2. 1 hit.
[Graphical view ]
SUPFAMi SSF55120. SSF55120. 1 hit.
TIGRFAMsi TIGR00093. TIGR00093. 1 hit.
PROSITEi PS01149. PSI_RSU. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: LT2 / SGSC1412 / ATCC 700720.

Entry informationi

Entry nameiRLUE_SALTY
AccessioniPrimary (citable) accession number: Q8ZPZ1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 15, 2003
Last sequence update: March 1, 2002
Last modified: October 1, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3