Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8ZPZ1

- RLUE_SALTY

UniProt

Q8ZPZ1 - RLUE_SALTY

Protein

Ribosomal large subunit pseudouridine synthase E

Gene

rluE

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Responsible for synthesis of pseudouridine from uracil-2457 in 23S ribosomal RNA.By similarity

    Catalytic activityi

    23S rRNA uridine(2457) = 23S rRNA pseudouridine(2457).

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei79 – 791NucleophileBy similarity

    GO - Molecular functioni

    1. pseudouridine synthase activity Source: InterPro
    2. RNA binding Source: InterPro

    GO - Biological processi

    1. pseudouridine synthesis Source: InterPro
    2. rRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    rRNA processing

    Enzyme and pathway databases

    BioCyciSENT99287:GCTI-1246-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribosomal large subunit pseudouridine synthase E (EC:5.4.99.20)
    Alternative name(s):
    rRNA pseudouridylate synthase E
    rRNA-uridine isomerase E
    Gene namesi
    Name:rluE
    Ordered Locus Names:STM1237
    OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
    Taxonomic identifieri99287 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
    ProteomesiUP000001014: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 221221Ribosomal large subunit pseudouridine synthase EPRO_0000100008Add
    BLAST

    Proteomic databases

    PaxDbiQ8ZPZ1.
    PRIDEiQ8ZPZ1.

    Interactioni

    Protein-protein interaction databases

    STRINGi99287.STM1237.

    Structurei

    3D structure databases

    ProteinModelPortaliQ8ZPZ1.
    SMRiQ8ZPZ1. Positions 36-215.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the pseudouridine synthase RsuA family.Curated

    Phylogenomic databases

    eggNOGiCOG1187.
    HOGENOMiHOG000044955.
    KOiK06181.
    OMAiLFNKPFQ.
    OrthoDBiEOG6130DV.
    PhylomeDBiQ8ZPZ1.

    Family and domain databases

    InterProiIPR020103. PsdUridine_synth_cat_dom.
    IPR000748. PsdUridine_synth_RsuA/RluB/E/F.
    IPR018496. PsdUridine_synth_RsuA/RluB_CS.
    IPR006145. PsdUridine_synth_RsuA/RluD.
    [Graphical view]
    PfamiPF00849. PseudoU_synth_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF55120. SSF55120. 1 hit.
    TIGRFAMsiTIGR00093. TIGR00093. 1 hit.
    PROSITEiPS01149. PSI_RSU. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8ZPZ1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRQLISSENT MQKTSFRNHY VKRFSSRQAS KSRKENQPKR VVLFNKPYDV    50
    LPQFTDEAGR RTLKDFIPVQ GVYAAGRLDR DSEGLLVLTN DGALQARLTQ 100
    PGKRTGKIYY VQVEGIPDNA ALQALRTGVT LNDGPTLPAG IEIVAEPDWL 150
    WPRTPPIRER KNIPTSWLKV TLYEGRNRQV RRMTAHVGHP TLRLIRYSMG 200
    DYTLNGLDNG QWREIAQEKD R 221
    Length:221
    Mass (Da):25,330
    Last modified:March 1, 2002 - v1
    Checksum:i41C5F9A2FFFE6F56
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006468 Genomic DNA. Translation: AAL20166.1.
    RefSeqiNP_460207.1. NC_003197.1.

    Genome annotation databases

    EnsemblBacteriaiAAL20166; AAL20166; STM1237.
    GeneIDi1252755.
    KEGGistm:STM1237.
    PATRICi32380927. VBISalEnt20916_1308.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006468 Genomic DNA. Translation: AAL20166.1 .
    RefSeqi NP_460207.1. NC_003197.1.

    3D structure databases

    ProteinModelPortali Q8ZPZ1.
    SMRi Q8ZPZ1. Positions 36-215.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 99287.STM1237.

    Proteomic databases

    PaxDbi Q8ZPZ1.
    PRIDEi Q8ZPZ1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL20166 ; AAL20166 ; STM1237 .
    GeneIDi 1252755.
    KEGGi stm:STM1237.
    PATRICi 32380927. VBISalEnt20916_1308.

    Phylogenomic databases

    eggNOGi COG1187.
    HOGENOMi HOG000044955.
    KOi K06181.
    OMAi LFNKPFQ.
    OrthoDBi EOG6130DV.
    PhylomeDBi Q8ZPZ1.

    Enzyme and pathway databases

    BioCyci SENT99287:GCTI-1246-MONOMER.

    Family and domain databases

    InterProi IPR020103. PsdUridine_synth_cat_dom.
    IPR000748. PsdUridine_synth_RsuA/RluB/E/F.
    IPR018496. PsdUridine_synth_RsuA/RluB_CS.
    IPR006145. PsdUridine_synth_RsuA/RluD.
    [Graphical view ]
    Pfami PF00849. PseudoU_synth_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55120. SSF55120. 1 hit.
    TIGRFAMsi TIGR00093. TIGR00093. 1 hit.
    PROSITEi PS01149. PSI_RSU. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LT2 / SGSC1412 / ATCC 700720.

    Entry informationi

    Entry nameiRLUE_SALTY
    AccessioniPrimary (citable) accession number: Q8ZPZ1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 15, 2003
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3