Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q8ZPR4 (YDIB_SALTY) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Quinate/shikimate dehydrogenase
EC=1.1.1.282
Alternative name(s):
NAD-dependent shikimate 5-dehydrogenase 2
Gene names
Name:ydiB
Ordered Locus Names:STM1359
OrganismSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) [Reference proteome] [HAMAP]
Taxonomic identifier99287 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella ›

Protein attributes

Sequence length288 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

L-quinate + NAD(P)+ = 3-dehydroquinate + NAD(P)H. HAMAP-Rule MF_01578

Shikimate + NAD(P)+ = 3-dehydroshikimate + NAD(P)H. HAMAP-Rule MF_01578

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7. HAMAP-Rule MF_01578

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the shikimate dehydrogenase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 288288Quinate/shikimate dehydrogenase HAMAP-Rule MF_01578
PRO_0000136072

Regions

Nucleotide binding131 – 1355NAD By similarity
Nucleotide binding155 – 1584NAD By similarity
Nucleotide binding255 – 2595NAD By similarity

Sites

Active site711Proton acceptor Potential
Binding site1071Substrate By similarity
Binding site2051NAD; via amide nitrogen By similarity
Binding site2351NAD By similarity

Secondary structure

1 ..................................................... 288
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q8ZPR4 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 42984154DE6BB962

FASTA28831,337
        10         20         30         40         50         60 
MDVTAKYELI GLMAYPIRHS LSPEMQNKAL EKAGLPYTYM AFEVDNTTFA SAIEGLKALK 

        70         80         90        100        110        120 
MRGTGVSMPN KQLACEYVDE LTPAAKLVGA INTIVNDDGY LRGYNTDGTG HIRAIKESGF 

       130        140        150        160        170        180 
DMRGKTMVLL GAGGAATAIG AQAAIEGIKE IKLFNRKDDF FEKAVAFAKR VNENTDCVVT 

       190        200        210        220        230        240 
VTDLADQHAF TEALASADIL TNGTKVGMKP LENESLIGDV SLLRPELLVT ECVYNPHMTK 

       250        260        270        280 
LLQQAQQAGC KTIDGYGMLL WQGAEQFELW TGKAFPLDYV KQVMGFTA

« Hide

References

[1]"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2."
McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E. expand/collapse author list , Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K.
Nature 413:852-856(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: LT2 / SGSC1412 / ATCC 700720.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE006468 Genomic DNA. Translation: AAL20284.1.
RefSeqNP_460325.1. NC_003197.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3T4EX-ray1.95A/B1-288[»]
ProteinModelPortalQ8ZPR4.
SMRQ8ZPR4. Positions 1-288.
ModBaseSearch...

Protein-protein interaction databases

STRING99287.STM1359.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL20284; AAL20284; STM1359.
GeneID1252877.
KEGGstm:STM1359.
PATRIC32381201. VBISalEnt20916_1443.

Phylogenomic databases

eggNOGCOG0169.
HOGENOMHOG000237875.
KOK05887.
OMATAIEIQA.
ProtClustDBPRK12749.

Enzyme and pathway databases

UniPathwayUPA00053; UER00087.

Family and domain databases

Gene3D3.40.50.720. 1 hit.
HAMAPMF_01578. Shikimate_DH_YdiB.
InterProIPR016040. NAD(P)-bd_dom.
IPR022872. Quinate/Shikimate_DH.
IPR013708. Shikimate_DH-bd_N.
IPR022893. Shikimate_quinate_DH.
IPR006151. Shikm_DH/Glu-tRNA_Rdtase.
[Graphical view]
PfamPF01488. Shikimate_DH. 1 hit.
PF08501. Shikimate_dh_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameYDIB_SALTY
AccessionPrimary (citable) accession number: Q8ZPR4
Entry history
Integrated into UniProtKB/Swiss-Prot: October 19, 2002
Last sequence update: March 1, 2002
Last modified: May 1, 2013
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents