Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q8ZPR4

- YDIB_SALTY

UniProt

Q8ZPR4 - YDIB_SALTY

Protein

Quinate/shikimate dehydrogenase

Gene

ydiB

Organism
Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 88 (01 Oct 2014)
      Sequence version 1 (01 Mar 2002)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    L-quinate + NAD(P)+ = 3-dehydroquinate + NAD(P)H.UniRule annotation
    Shikimate + NAD(P)+ = 3-dehydroshikimate + NAD(P)H.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei71 – 711Proton acceptorUniRule annotation
    Binding sitei107 – 1071SubstrateUniRule annotation
    Binding sitei205 – 2051NAD; via amide nitrogenUniRule annotation
    Binding sitei235 – 2351NADUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi131 – 1355NADUniRule annotation
    Nucleotide bindingi155 – 1584NADUniRule annotation
    Nucleotide bindingi255 – 2595NADUniRule annotation

    GO - Molecular functioni

    1. quinate 3-dehydrogenase (NAD+) activity Source: UniProtKB-HAMAP
    2. quinate 3-dehydrogenase (NADP+) activity Source: UniProtKB-EC
    3. shikimate 3-dehydrogenase (NAD+) activity Source: UniProtKB-EC
    4. shikimate 3-dehydrogenase (NADP+) activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. aromatic amino acid family biosynthetic process Source: UniProtKB-HAMAP
    2. chorismate biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Amino-acid biosynthesis, Aromatic amino acid biosynthesis

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciSENT99287:GCTI-1369-MONOMER.
    UniPathwayiUPA00053; UER00087.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Quinate/shikimate dehydrogenaseUniRule annotation (EC:1.1.1.282UniRule annotation)
    Alternative name(s):
    NAD-dependent shikimate 5-dehydrogenase 2UniRule annotation
    Gene namesi
    Name:ydiBUniRule annotation
    Ordered Locus Names:STM1359
    OrganismiSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
    Taxonomic identifieri99287 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella
    ProteomesiUP000001014: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 288288Quinate/shikimate dehydrogenasePRO_0000136072Add
    BLAST

    Interactioni

    Subunit structurei

    Homodimer.UniRule annotation

    Protein-protein interaction databases

    STRINGi99287.STM1359.

    Structurei

    Secondary structure

    1
    288
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi8 – 158
    Helixi22 – 3312
    Beta strandi36 – 438
    Turni46 – 483
    Helixi49 – 5810
    Beta strandi63 – 664
    Helixi71 – 744
    Helixi75 – 773
    Beta strandi79 – 813
    Helixi83 – 886
    Beta strandi92 – 976
    Beta strandi100 – 1045
    Helixi106 – 11712
    Beta strandi126 – 1305
    Helixi134 – 14512
    Beta strandi149 – 1557
    Helixi160 – 17415
    Beta strandi178 – 1836
    Helixi187 – 19610
    Beta strandi198 – 2025
    Helixi220 – 2223
    Beta strandi228 – 2314
    Beta strandi235 – 2384
    Helixi240 – 2478
    Beta strandi251 – 2533
    Helixi255 – 27117
    Helixi277 – 2837

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3T4EX-ray1.95A/B1-288[»]
    ProteinModelPortaliQ8ZPR4.
    SMRiQ8ZPR4. Positions 1-288.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the shikimate dehydrogenase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0169.
    HOGENOMiHOG000237875.
    KOiK05887.
    OMAiGNVTLPH.
    OrthoDBiEOG64R67G.
    PhylomeDBiQ8ZPR4.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    HAMAPiMF_00222. Shikimate_DH_AroE.
    MF_01578. Shikimate_DH_YdiB.
    InterProiIPR016040. NAD(P)-bd_dom.
    IPR022872. Quinate/Shikimate_DH.
    IPR013708. Shikimate_DH-bd_N.
    IPR022893. Shikimate_quinate_DH.
    IPR006151. Shikm_DH/Glu-tRNA_Rdtase.
    [Graphical view]
    PfamiPF01488. Shikimate_DH. 1 hit.
    PF08501. Shikimate_dh_N. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q8ZPR4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDVTAKYELI GLMAYPIRHS LSPEMQNKAL EKAGLPYTYM AFEVDNTTFA    50
    SAIEGLKALK MRGTGVSMPN KQLACEYVDE LTPAAKLVGA INTIVNDDGY 100
    LRGYNTDGTG HIRAIKESGF DMRGKTMVLL GAGGAATAIG AQAAIEGIKE 150
    IKLFNRKDDF FEKAVAFAKR VNENTDCVVT VTDLADQHAF TEALASADIL 200
    TNGTKVGMKP LENESLIGDV SLLRPELLVT ECVYNPHMTK LLQQAQQAGC 250
    KTIDGYGMLL WQGAEQFELW TGKAFPLDYV KQVMGFTA 288
    Length:288
    Mass (Da):31,337
    Last modified:March 1, 2002 - v1
    Checksum:i42984154DE6BB962
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006468 Genomic DNA. Translation: AAL20284.1.
    RefSeqiNP_460325.1. NC_003197.1.

    Genome annotation databases

    EnsemblBacteriaiAAL20284; AAL20284; STM1359.
    GeneIDi1252877.
    KEGGistm:STM1359.
    PATRICi32381201. VBISalEnt20916_1443.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE006468 Genomic DNA. Translation: AAL20284.1 .
    RefSeqi NP_460325.1. NC_003197.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3T4E X-ray 1.95 A/B 1-288 [» ]
    ProteinModelPortali Q8ZPR4.
    SMRi Q8ZPR4. Positions 1-288.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 99287.STM1359.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAL20284 ; AAL20284 ; STM1359 .
    GeneIDi 1252877.
    KEGGi stm:STM1359.
    PATRICi 32381201. VBISalEnt20916_1443.

    Phylogenomic databases

    eggNOGi COG0169.
    HOGENOMi HOG000237875.
    KOi K05887.
    OMAi GNVTLPH.
    OrthoDBi EOG64R67G.
    PhylomeDBi Q8ZPR4.

    Enzyme and pathway databases

    UniPathwayi UPA00053 ; UER00087 .
    BioCyci SENT99287:GCTI-1369-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    HAMAPi MF_00222. Shikimate_DH_AroE.
    MF_01578. Shikimate_DH_YdiB.
    InterProi IPR016040. NAD(P)-bd_dom.
    IPR022872. Quinate/Shikimate_DH.
    IPR013708. Shikimate_DH-bd_N.
    IPR022893. Shikimate_quinate_DH.
    IPR006151. Shikm_DH/Glu-tRNA_Rdtase.
    [Graphical view ]
    Pfami PF01488. Shikimate_DH. 1 hit.
    PF08501. Shikimate_dh_N. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: LT2 / SGSC1412 / ATCC 700720.

    Entry informationi

    Entry nameiYDIB_SALTY
    AccessioniPrimary (citable) accession number: Q8ZPR4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 19, 2002
    Last sequence update: March 1, 2002
    Last modified: October 1, 2014
    This is version 88 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3