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Q8ZMX8 (TRMN6_SALTY) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
tRNA1(Val) (adenine(37)-N6)-methyltransferase
EC=2.1.1.223
Alternative name(s):
tRNA m6A37 methyltransferase
Gene names
Name:yfiC
Ordered Locus Names:STM2642
OrganismSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) [Reference proteome] [HAMAP]
Taxonomic identifier99287 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella ›

Protein attributes

Sequence length245 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Specifically methylates the adenine in position 37 of tRNA1(Val) (anticodon cmo5UAC) By similarity. HAMAP-Rule MF_01872

Catalytic activity

S-adenosyl-L-methionine + adenine37 in tRNA1(Val) = S-adenosyl-L-homocysteine + N(6)-methyladenine37 in tRNA1(Val). HAMAP-Rule MF_01872

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_01872.

Sequence similarities

Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.

Ontologies

Keywords
   Biological processtRNA processing
   Cellular componentCytoplasm
   LigandS-adenosyl-L-methionine
   Molecular functionMethyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionnucleic acid binding

Inferred from electronic annotation. Source: InterPro

tRNA (adenine-N6-)-methyltransferase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 245245tRNA1(Val) (adenine(37)-N6)-methyltransferase HAMAP-Rule MF_01872
PRO_0000387412

Sequences

Sequence LengthMass (Da)Tools
Q8ZMX8 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: C5E24BFA203B1B4D

FASTA24527,307
        10         20         30         40         50         60 
MSQSGSVLRR NGFTFKQFFV AHDRCAMKVG TDGILLGAWA PVADVKRILD IGTGSGLLAL 

        70         80         90        100        110        120 
MLAQRTDDNV PIDAVELDAG AAMQAQENVA HSPWPHRITV HTDDIQRWAP RQTVRFDLII 

       130        140        150        160        170        180 
SNPPYYEPGV ECATPQREQA RYTATLDHQT LLAIAADCIT EDGFFCVVLP EQIGNAFTQQ 

       190        200        210        220        230        240 
ALNMGWHLRL RTDVAENEAR LPHRVLLAFS PQAGECFSDR LVIRGSDQHY SESYTALTQA 


FYLFM

« Hide

References

[1]"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2."
McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E. expand/collapse author list , Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K.
Nature 413:852-856(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: LT2 / SGSC1412 / ATCC 700720.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE006468 Genomic DNA. Translation: AAL21536.1.
RefSeqNP_461577.1. NC_003197.1.

3D structure databases

ProteinModelPortalQ8ZMX8.
ModBaseSearch...

Protein-protein interaction databases

STRING99287.STM2642.

Proteomic databases

PaxDbQ8ZMX8.
PRIDEQ8ZMX8.

Protocols and materials databases

DNASU1254165.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL21536; AAL21536; STM2642.
GeneID1254165.
KEGGstm:STM2642.
PATRIC32383941. VBISalEnt20916_2792.

Phylogenomic databases

eggNOGCOG4123.
HOGENOMHOG000283147.
KOK15460.
OMAFKQFHIN.
ProtClustDBCLSK2391290.

Family and domain databases

HAMAPMF_01872. tRNA_methyltr_YfiC.
InterProIPR002052. DNA_methylase_N6_adenine_CS.
IPR022882. tRNA_adenine-N6_MeTrfase.
[Graphical view]
PROSITEPS00092. N6_MTASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTRMN6_SALTY
AccessionPrimary (citable) accession number: Q8ZMX8
Entry history
Integrated into UniProtKB/Swiss-Prot: November 3, 2009
Last sequence update: March 1, 2002
Last modified: May 1, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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