Reviewed, UniProtKB/Swiss-Prot Q8ZMC5 (FUCK_SALTY)

Names and origin

Protein names

Recommended name:
    L-fuculokinase
    EC=2.7.1.51
Alternative name(s):
    L-fuculose kinase

Gene names

Name:	fucK
Ordered Locus Names:	STM2977

Organism

Salmonella typhimurium [Complete proteome] [HAMAP]

Taxonomic identifier

90371 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	472 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-fuculose = ADP + L-fuculose 1-phosphate.
Pathway	Carbohydrate degradation; L-fucose degradation; L-lactaldehyde and glycerone phosphate from L-fucose: step 2/3.
Sequence similarities	Belongs to the FGGY kinase family.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Fucose metabolism
Ligand	ATP-binding Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	fucose metabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW L-fuculokinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 472	472	L-fuculokinase		PRO_0000059427

Sequences

	Sequence		Length	Mass (Da)
	Q8ZMC5-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 0AAC72FC94BCBF72	FASTA	472	51,674
	10 20 30 40 50 60 MKQDVILVLD CGATNVRAIA VDRQGKIVAR ASTANASDIA AENSAWHQWS LDAILQRFAD 70 80 90 100 110 120 CCRSLSSALS ECVVRGITVT TFGVDGALVD AQGKLLYPVI SWKCPRTAAV METIERFISP 130 140 150 160 170 180 RQLQTLSGVG AFSFNTLYKL VWLKENHPRL LEQAHCWLFI SSLINHRLTG EFTTDITMAG 190 200 210 220 230 240 TSQLLDIHQR DFSPEILQAT GLARRLFPRI VEAGAPIGTL QTDAARLLGL PAGVPVISAG 250 260 270 280 290 300 HDTQFALFGA GAQQGEPVLS SGTWEILMVR SGQVDTSLLS QYPGSTCELD SQSGLYNPGM 310 320 330 340 350 360 QWLASGVLEW VRKLLWTPET PWQTLIDEAR AIPAGAEGVR MQCDLLACQN AGWQGVTLNT 370 380 390 400 410 420 TRGHFYRAAL EGLTAQLQRN LRTLEKIGHF NATELLLVGG GSRNALWNQI KANQLDIPIK 430 440 450 460 470 VLDDAETTVA GAAMFGWYGV GEFSSPEQAR AQVNYQYRYF WPQTEPEIIE GV

References

[1]

"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2." McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E. , Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K. Nature 413:852-856(2001) [PubMed: 11677609] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LT2 / SGSC1412 / ATCC 700720.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE008836 Genomic DNA. Translation: AAL21855.1.
RefSeq	NP_461896.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1254500.
GenomeReviews	Gene locus STM2977 in contig AE006468_GR.
KEGG	stm:STM2977.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q8ZMC5.
OMA	Q8ZMC5. ATNVRAM.
Enzyme and pathway databases
BioCyc	STYP99287:STM2977-MON.
BRENDA	2.7.1.51. 2.
Family and domain databases
InterPro	IPR000577. Carb_kinase_FGGY. IPR018485. Carb_kinase_FGGY_C. IPR018483. Carb_kinase_FGGY_CS. IPR018484. Carb_kinase_FGGY_N. IPR013450. Fuculokinase. [Graphical view]
PANTHER	PTHR10196. FGGY_kin. 1 hit.
Pfam	PF02782. FGGY_C. 1 hit. PF00370. FGGY_N. 1 hit. [Graphical view]
TIGRFAMs	TIGR02628. fuculo_kin_coli. 1 hit.
PROSITE	PS00933. FGGY_KINASES_1. 1 hit. PS00445. FGGY_KINASES_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FUCK_SALTY

Accession

Primary (citable) accession number: Q8ZMC5

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 11, 2002
Last sequence update:	March 1, 2002
Last modified:	June 16, 2009
This is version 34 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)