Putative sugar kinase - Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

Preferred order of sections

Names and origin

Protein names

Submitted name:
Putative sugar kinase EMBL AAL22906.1
EC=2.7.1.4 EMBL AAL22906.1
EC=3.6.1.26 EMBL AAL22906.1

Gene names

Ordered Locus Names:

STM4066 EMBL AAL22906.1

Organism

Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) [Reference proteome] [HAMAP] EMBL AAL22906.1

Taxonomic identifier

99287 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella ›

Protein attributes

Sequence length	319 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the carbohydrate kinase pfkB family. RuleBase RU003704

Ontologies

Keywords
Molecular function	Hydrolase EMBL AAL22906.1 Kinase RuleBase RU003704 SAAS SAAS011611 EMBL AAL22906.1 Transferase
Technical term	3D-structure PDB 1TYY PDB 1TZ3 PDB 1TZ6 Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	D-ribose metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	CDP-diacylglycerol diphosphatase activity Inferred from electronic annotation. Source: EC fructokinase activity Inferred from electronic annotation. Source: EC ribokinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Sites

Active site

252

1

Proton donor/acceptor PDB 1TZ3

Site

249

1

Transition state stabilizer; via amide nitrogen PDB 1TZ3

Site

250

1

Transition state stabilizer; via amide nitrogen PDB 1TZ3

Site

251

1

Transition state stabilizer; via amide nitrogen PDB 1TZ3

Sequences

Sequence

Length

Mass (Da)

Tools

Q8ZKR2 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: A899A6735BC25D66
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FASTA

319

34,238

        10         20         30         40         50         60 
MKAMNKVWVI GDASVDLVPE KQNSYLKCPG GASANVGVCV ARLGGECGFI GCLGDDDAGR 

        70         80         90        100        110        120 
FLRQVFQDNG VDVTFLRLDA DLTSAVLIVN LTADGERSFT YLVHPGADTY VSPQDLPPFR 

       130        140        150        160        170        180 
QYEWFYFSSI GLTDRPAREA CLEGARRMRE AGGYVLFDVN LRSKMWGNTD EIPELIARSA 

       190        200        210        220        230        240 
ALASICKVSA DELCQLSGAS HWQDARYYLR DLGCDTTIIS LGADGALLIT AEGEFHFPAP 

       250        260        270        280        290        300 
RVDVVDTTGA GDAFVGGLLF TLSRANCWDH ALLAEAISNA NACGAMAVTA KGAMTALPFP 

       310 
DQLNTFLSSH SLAQAMTVK

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References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2." McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E. Wilson R.K. Nature 413:852-856(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LT2 / SGSC1412 / ATCC 700720.
[2]	"Crystal structure of an aminoimidazole riboside kinase from Salmonella enterica: implications for the evolution of the ribokinase superfamily." Zhang Y., Dougherty M., Downs D.M., Ealick S.E. Structure 12:1809-1821(2004) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.60 ANGSTROMS), ACTIVE SITE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE006468 Genomic DNA. Translation: AAL22906.1.

RefSeq

NP_462947.1. NC_003197.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1TYY	X-ray	2.60	A/B	1-319	[»]
1TZ3	X-ray	2.90	A/B	1-319	[»]
1TZ6	X-ray	2.70	A/B	1-319	[»]

ProteinModelPortal

Q8ZKR2.

SMR

Q8ZKR2. Positions 5-310.

ModBase

Search...

Protein-protein interaction databases

STRING

99287.STM4066.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAL22906; AAL22906; STM4066.

GeneID

1255593.

KEGG

stm:STM4066.

PATRIC

32387012. VBISalEnt20916_4286.

Phylogenomic databases

HOGENOM

HOG000235951.

KO

K00847.

OMA

ICGALAT.

ProtClustDB

PRK09434.

Family and domain databases

InterPro

IPR002173. Carboh/pur_kinase_PfkB_CS.
IPR011611. PfkB_dom.
IPR002139. Ribokinase.
[Graphical view]

Pfam

PF00294. PfkB. 1 hit.
[Graphical view]

PRINTS

PR00990. RIBOKINASE.

PROSITE

PS00584. PFKB_KINASES_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q8ZKR2.

Entry information

Entry name

Q8ZKR2_SALTY

Accession

Primary (citable) accession number: Q8ZKR2

Entry history

Integrated into UniProtKB/TrEMBL:	March 1, 2002
Last sequence update:	March 1, 2002
Last modified:	May 1, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)