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Q8ZKI0 (UBIC_SALTY) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chorismate--pyruvate lyase
Short name=CL
Short name=CPL
EC=4.1.3.40
Gene names
Name:ubiC
Ordered Locus Names:STM4233
OrganismSalmonella typhimurium
Taxonomic identifier90371 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length165 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway By similarity. HAMAP MF_01632

Catalytic activity

Chorismate = 4-hydroxybenzoate + pyruvate. HAMAP MF_01632

Pathway

Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_01632

Subunit structure

Monomer By similarity. HAMAP MF_01632

Subcellular location

Cytoplasm By similarity HAMAP MF_01632.

Sequence similarities

Belongs to the ubiC family.

Ontologies

Keywords
   Biological processUbiquinone biosynthesis
   Cellular componentCytoplasm
   LigandPyruvate
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processubiquinone biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionchorismate lyase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 165165Chorismate--pyruvate lyase HAMAP MF_01632
PRO_0000240571

Sites

Binding site351Substrate; via amide nitrogen By similarity
Binding site771Substrate By similarity
Binding site1151Substrate; via amide nitrogen By similarity

Sequences

Sequence LengthMass (Da)Tools
Q8ZKI0 [UniParc].

Last modified March 1, 2002. Version 1.
Checksum: 98658AEEC6EF54D1

FASTA16518,720
        10         20         30         40         50         60 
MSHPALTQLR ALRYFDAIPA LEPHLLDWLL LEDSMTKRFE QQGKRVSVTL IREAFVGQSE 

        70         80         90        100        110        120 
VEEASGLLPS ESRYWLREIL LCADGEPWLA GRTVVPESTL CGPEQVLQHL GKTPLGRYLF 

       130        140        150        160 
TSSTLTRDFI EIGRDATLWG RRSRLRLSGK PLLLTELFLP ASPLY

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE006468 Genomic DNA. Translation: AAL23057.1.
RefSeqNP_463098.1. NC_003197.1.

3D structure databases

ProteinModelPortalQ8ZKI0.
SMRQ8ZKI0. Positions 2-165.
ModBaseSearch...

Proteomic databases

PRIDEQ8ZKI0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1255759.
GenomeReviewsGene locus STM4233 in contig AE006468_GR.
KEGGstm:STM4233.
PATRIC32387371. VBISalEnt20916_4453.

Phylogenomic databases

HOGENOMHBG644467.
OMAGRTVIPQ.
ProtClustDBPRK11655.

Enzyme and pathway databases

BioCycSTYP99287:STM4233-MONOMER.

Family and domain databases

HAMAPMF_01632. UbiC.
[Tree]
InterProIPR007440. Chorismate--pyruvate_lyase.
[Graphical view]
KOK03181.
PfamPF04345. Chor_lyase. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUBIC_SALTY
AccessionPrimary (citable) accession number: Q8ZKI0
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: March 1, 2002
Last modified: January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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