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Protein

Glutathione-regulated potassium-efflux system ancillary protein KefG

Gene

kefG

Organism
Yersinia pestis
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.UniRule annotation

Catalytic activityi

NAD(P)H + a quinone = NAD(P)+ + a hydroquinone.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione-regulated potassium-efflux system ancillary protein KefGUniRule annotation
Alternative name(s):
Putative quinone oxidoreductase KefGUniRule annotation (EC:1.6.5.2UniRule annotation)
Gene namesi
Name:kefGUniRule annotation
Ordered Locus Names:YPO0190, y3971, YP_0188
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesYersiniaceaeYersinia
Proteomesi
  • UP000000815 Componenti: Chromosome
  • UP000001019 Componenti: Chromosome
  • UP000002490 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation; Cytoplasmic side UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000716501 – 183Glutathione-regulated potassium-efflux system ancillary protein KefGAdd BLAST183

Proteomic databases

PaxDbiQ8ZJC5

Interactioni

Subunit structurei

Interacts with KefB.UniRule annotation

Protein-protein interaction databases

IntActiQ8ZJC5, 1 interactor
STRINGi187410.y3971

Structurei

3D structure databases

ProteinModelPortaliQ8ZJC5
SMRiQ8ZJC5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108K2R Bacteria
COG2249 LUCA
HOGENOMiHOG000149972
KOiK11748
OMAiRYPMSDI

Family and domain databases

Gene3Di3.40.50.360, 1 hit
HAMAPiMF_01415 K_H_efflux_KefG, 1 hit
InterProiView protein in InterPro
IPR003680 Flavodoxin_fold
IPR029039 Flavoprotein-like_sf
IPR023947 K_H_efflux_KefG
PfamiView protein in Pfam
PF02525 Flavodoxin_2, 1 hit
SUPFAMiSSF52218 SSF52218, 1 hit

Sequencei

Sequence statusi: Complete.

Q8ZJC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMLQPPKVLL LYAHPESQDS VANRVLLQPV QQLEHVTVHD LYAHYPDFFI
60 70 80 90 100
DIHHEQQLLR DHQVIVFQHP LYTYSCPALL KEWLDRVLAR GFANGVGGHA
110 120 130 140 150
LTGKHWRSVI TTGEQEGTYR IGGYNRYPME DILRPFELTA AMCHMHWINP
160 170 180
MIIYWARRQK PETLASHAQA YVQWLQSPLT RGL
Length:183
Mass (Da):21,332
Last modified:March 1, 2002 - v1
Checksum:iA31EBB7E44A2B567
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA Translation: CAL18874.1
AE009952 Genomic DNA Translation: AAM87515.1
AE017042 Genomic DNA Translation: AAS60464.1
PIRiAI0023
RefSeqiWP_002212313.1, NZ_PDBR01000008.1
YP_002345272.1, NC_003143.1

Genome annotation databases

EnsemblBacteriaiAAM87515; AAM87515; y3971
AAS60464; AAS60464; YP_0188
GeneIDi1173034
KEGGiype:YPO0190
ypk:y3971
ypm:YP_0188
PATRICifig|214092.21.peg.422

Similar proteinsi

Entry informationi

Entry nameiKEFG_YERPE
AccessioniPrimary (citable) accession number: Q8ZJC5
Secondary accession number(s): Q0WKB6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2003
Last sequence update: March 1, 2002
Last modified: March 28, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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