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Protein

Purine nucleoside phosphorylase DeoD-type

Gene

deoD

Organism
Yersinia pestis
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate.UniRule annotation
Purine deoxynucleoside + phosphate = purine + 2'-deoxy-alpha-D-ribose 1-phosphate.UniRule annotation

GO - Molecular functioni

  1. purine-nucleoside phosphorylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. purine nucleoside metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Enzyme and pathway databases

BioCyciYPES214092:GKDD-436-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Purine nucleoside phosphorylase DeoD-typeUniRule annotation (EC:2.4.2.1UniRule annotation)
Short name:
PNPUniRule annotation
Gene namesi
Name:deoDUniRule annotation
Ordered Locus Names:YPO0440, y3740, YP_3742
OrganismiYersinia pestis
Taxonomic identifieri632 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000000815 Componenti: Chromosome UP000001019 Componenti: Chromosome UP000002490 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 239239Purine nucleoside phosphorylase DeoD-typePRO_0000063181Add
BLAST

Proteomic databases

PRIDEiQ8ZIQ2.

Interactioni

Subunit structurei

Homohexamer.UniRule annotation

Protein-protein interaction databases

STRINGi214092.YPO0440.

Structurei

3D structure databases

ProteinModelPortaliQ8ZIQ2.
SMRiQ8ZIQ2. Positions 2-237.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PNP/UDP phosphorylase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0813.
HOGENOMiHOG000274896.
KOiK03784.
OMAiIRNDWPQ.
OrthoDBiEOG6BKJC5.

Family and domain databases

Gene3Di3.40.50.1580. 1 hit.
HAMAPiMF_01627. Pur_nucleosid_phosp.
InterProiIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERiPTHR21234. PTHR21234. 1 hit.
PfamiPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMiSSF53167. SSF53167. 1 hit.
TIGRFAMsiTIGR00107. deoD. 1 hit.
PROSITEiPS01232. PNP_UDP_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q8ZIQ2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATPHINAEM GDFADVVLMP GDPLRAKFIA ETFLQDVREV NNVRGMLGFT
60 70 80 90 100
GTYKGRKISV MGHGMGIPSC SIYAKELITD FGVKKIIRVG SCGAVRTDVK
110 120 130 140 150
LRDVVIGMGA CTDSKVNRMR FKDHDYAAIA DFEMTRNAVD AAKAKGVNVR
160 170 180 190 200
VGNLFSADLF YTPDPQMFDV MEKYGILGVE MEAAGICGVA AEFGAKALTI
210 220 230
CTVSDHIRTG EQTTAAERQT TFNDMIEIAL ESVLLGDNA
Length:239
Mass (Da):25,876
Last modified:February 28, 2002 - v1
Checksum:i6E4A15BFBBA9A209
GO

Sequence cautioni

The sequence AAM87286.1 differs from that shown. Reason: Erroneous initiation. Curated
The sequence AAS63890.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA. Translation: CAL19120.1.
AE009952 Genomic DNA. Translation: AAM87286.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS63890.1. Different initiation.
PIRiAF0054.
RefSeqiNP_671035.1. NC_004088.1.
NP_995013.1. NC_005810.1.
WP_002209217.1. NZ_KN150724.1.
YP_002345514.1. NC_003143.1.

Genome annotation databases

EnsemblBacteriaiAAM87286; AAM87286; y3740.
AAS63890; AAS63890; YP_3742.
GeneIDi1173285.
KEGGiype:YPO0440.
ypk:y3740.
ypm:YP_3742.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL590842 Genomic DNA. Translation: CAL19120.1.
AE009952 Genomic DNA. Translation: AAM87286.1. Different initiation.
AE017042 Genomic DNA. Translation: AAS63890.1. Different initiation.
PIRiAF0054.
RefSeqiNP_671035.1. NC_004088.1.
NP_995013.1. NC_005810.1.
WP_002209217.1. NZ_KN150724.1.
YP_002345514.1. NC_003143.1.

3D structure databases

ProteinModelPortaliQ8ZIQ2.
SMRiQ8ZIQ2. Positions 2-237.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi214092.YPO0440.

Proteomic databases

PRIDEiQ8ZIQ2.

Protocols and materials databases

DNASUi1148687.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAM87286; AAM87286; y3740.
AAS63890; AAS63890; YP_3742.
GeneIDi1173285.
KEGGiype:YPO0440.
ypk:y3740.
ypm:YP_3742.

Phylogenomic databases

eggNOGiCOG0813.
HOGENOMiHOG000274896.
KOiK03784.
OMAiIRNDWPQ.
OrthoDBiEOG6BKJC5.

Enzyme and pathway databases

BioCyciYPES214092:GKDD-436-MONOMER.

Family and domain databases

Gene3Di3.40.50.1580. 1 hit.
HAMAPiMF_01627. Pur_nucleosid_phosp.
InterProiIPR004402. DeoD-type.
IPR018017. Nucleoside_phosphorylase.
IPR018016. Nucleoside_phosphorylase_CS.
IPR000845. Nucleoside_phosphorylase_d.
[Graphical view]
PANTHERiPTHR21234. PTHR21234. 1 hit.
PfamiPF01048. PNP_UDP_1. 1 hit.
[Graphical view]
SUPFAMiSSF53167. SSF53167. 1 hit.
TIGRFAMsiTIGR00107. deoD. 1 hit.
PROSITEiPS01232. PNP_UDP_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CO-92 / Biovar Orientalis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: KIM10+ / Biovar Mediaevalis.
  3. "Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans."
    Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R.
    , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R.
    DNA Res. 11:179-197(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 91001 / Biovar Mediaevalis.

Entry informationi

Entry nameiDEOD_YERPE
AccessioniPrimary (citable) accession number: Q8ZIQ2
Secondary accession number(s): Q0WJM4, Q74PY9, Q8CZN9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 9, 2006
Last sequence update: February 28, 2002
Last modified: March 31, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.