Reviewed, UniProtKB/Swiss-Prot Q8ZHH8 (RPIA1_YERPE)

Names and origin

Protein names

Recommended name:
    Ribose-5-phosphate isomerase A 1
    EC=5.3.1.6
Alternative name(s):
    Phosphoriboisomerase A 1
      Short name=PRI 1

Gene names

Name:	rpiA1
Ordered Locus Names:	YPO0915, y3302, YP_3612

Organism

Yersinia pestis [Complete proteome] [HAMAP]

Taxonomic identifier

632 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Yersinia

Protein attributes

Sequence length	218 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: HAMAP
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 218	218	Ribose-5-phosphate isomerase A 1 HAMAP MF_00170		PRO_0000158501

Sequences

	Sequence		Length	Mass (Da)
	Q8ZHH8-1 [UniParc]. Last modified March 1, 2002. Version 1. Checksum: 44902D266E9EBE1C	FASTA	218	22,801
	10 20 30 40 50 60 MTQDELKKAV GWAALDYVKP GTIVGVGTGS TAAHFIDALG SIKHQIEGAV SSSDASTAKL 70 80 90 100 110 120 KSYGIPVFDC NDVDVLDIYV DGADEINGQM QMIKGGGAAL TREKIIAAIA RKFICIADES 130 140 150 160 170 180 KQVGVLGKFP LPVEVIPMAR SYVARELIKL GGLPEYRQNV LTDNGNVILD VHNLSILDAI 190 200 210 ALENQINGIA GVVTVGLFAN RGADVALIGT ANGVKVIG

References

[1]	"Genome sequence of Yersinia pestis, the causative agent of plague." Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G., Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L., Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M., Chillingworth T., Cronin A., Davies R.M. , Davis P., Dougan G., Feltwell T., Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S., Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S., Barrell B.G. Nature 413:523-527(2001) [PubMed: 11586360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CO-92 / Biovar Orientalis.
[2]	"Genome sequence of Yersinia pestis KIM." Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P., Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D., Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A., Nilles M.L. , Matson J.S., Blattner F.R., Perry R.D. J. Bacteriol. 184:4601-4611(2002) [PubMed: 12142430] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: KIM5 / Biovar Mediaevalis.
[3]	"Complete genome sequence of Yersinia pestis strain 91001, an isolate avirulent to humans." Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D., Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L., Dai R. , Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H., Wang J., Huang P., Yang R. DNA Res. 11:179-197(2004) [PubMed: 15368893] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 91001 / Biovar Mediaevalis.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL590842 Genomic DNA. Translation: CAL19582.1. AE009952 Genomic DNA. Translation: AAM86852.1. AE017042 Genomic DNA. Translation: AAS63762.1.
PIR	AD0112.
RefSeq	NP_670601.1. NP_994885.1. YP_002345963.1.
3D structure databases
SMR	Q8ZHH8. Positions 1-217.
ModBase	Search...
Genome annotation databases
GeneID	1148249. 1173752. 2765233.
GenomeReviews	Gene locus y3302 in contig AE009952_GR. Gene locus YP_3612 in contig AE017042_GR. Gene locus YPO0915 in contig AL590842_GR.
KEGG	ype:YPO0915. ypk:y3302. ypm:YP_3612.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG515603.
OMA	VFDLNSV.
Enzyme and pathway databases
BioCyc	YPES187410:Y3302-MONOMER. YPES214092:YPO0915-MONOMER. YPES229193:YP3612-MONOMER.
BRENDA	5.3.1.6. 142588.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A. [Tree]
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. [Graphical view]
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. rpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA1_YERPE

Accession

Primary (citable) accession number: Q8ZHH8
Secondary accession number(s): Q0WIC5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 23, 2003
Last sequence update:	March 1, 2002
Last modified:	February 9, 2010
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)